I agree, please give him another chance. Don't give up on him. I know it is a problem, but don't let your frustration get to you and then transfer to him. Take a deep breath, say a prayer. He isn't doing this to be mean or contrary, there is a problem that causes this. ---- Amani Oakley <[email protected]> wrote: > Jen > > Can I plead with you on Figaro’s behalf? I know how unbelievably disruptive > and disturbing it is to be peed on! I have had the pleasure. But very often > it signals something else is wrong. In my last cat who did this – who > squatted right on the bed while looking straight at me and peed, I oddly got > the sense that HE didn’t know why he had done it. I also noticed that he > seemed particularly disturbed in the litter box, and there were some other > oddities which I had noticed. It turned out that he had a lesion (could be a > small break) in his lower spinal cord (maybe his tail had been pulled or > caught in a door, etc), and these were neurological complications which were > resulting in this odd behaviour. The nerves which enervate the bladder and > bowel are found in the lower part of the spinal cord. Thus damage to that > area (a fall, hit by a car, tail caught in a door and the cat running hard in > the opposite direction) can all cause damage to these nerves. > > There are sometimes other explanations such as urinary tract infections, or > just not feeling right. > > I would think you think again about having him fixed. I agree with others who > have posted, that it should be okay to fix him if he is not experiencing any > FeLV symptoms yet. However, just to be on the safe side, you might consider > putting him on Doxycycline/Winstrol/Prednisone for a few weeks before the > surgery. There is a published study showing that people who were put on > Stanazolol (Winstrol) prior to abdominal surgery, had a better and faster > recovery than the control group who did not take Stanazolol. > > I think that the mortality rate may be due to the fact that surgery weakens > the body and if the cat is already battling an immune challenge, surgery may > be the straw that breaks the camel’s back. However, I would also think that > it would be female cats who would be more at risk. Neutering is not nearly as > invasive as spaying. > > Please don’t give up on him. He will have a very dim future, given his FeLV > status and peeing issues. > > From: Felvtalk [mailto:[email protected]] On Behalf Of > Jennifer Olson > Sent: March-02-17 8:39 AM > To: [email protected] > Subject: [Felvtalk] Losing patience > > Figaro is adorable, but I'm so frustrated with the whole situation- > I'm begining to consider other livining arrangements... aka placement... > > On Mar 2, 2017 3:19 AM, "ROBERT CHAPEL" > <[email protected]<mailto:[email protected]>> wrote: > Thanks Amani... this is very helpful and I will do my best to locate these > references... preferably the full articles if they don't charge too much for > them ( I no longer work in hospitals and don't have access to full medical > databases ( for free)... > > VERY interesting about the ebola virus and the eyes.... it does indeed appear > that the virus established a foothold in Yogi's eyes.... BUT... it was also > via the eyes that I was able to introduce antiviral meds that my Veterinary > opthalmologist was using off label..... Of course the target for these meds > was the Herpes Virus....but it too ,is, a retro Virus and these meds "might" > have had some effect on the FeLV virus as well > had I used them for a longer time ( though I would have had to have sold my > house to do so : ) > You can find ALL sorts of aid for these Anti Virals if you are using them for > HIV or Herpes 1 or 2 but they are hard to locate at discount for Veterinary > Use..... I really am VERY concerned at the price of Vet services as I feel > they will ultimately reduce the number of pet owners..... I was able to > easily afford to keep 4 cats on a rather low Social Worker income back in the > 80's but keeping one ill FeLV in 2017 can easily add 400.00 a month to ones > expenses.... Many people who might formerly have adopted multiple cats will > now only take in one or two..... All the more reason for forums like ours > as it is up to us to share our knowledge and experiences to help each other > avoid total reliance on a veterinary system that is not always working to > preserve our FeLV cats lives..... > > Hi Bob > > I am unable to attach the literature regarding the ability of Doxycycline to > interfere with RNA replication and/or interfere with viral infection, but > here are a few titles to look up on the Internet: > > - Antiviral activity of doxycycline against vesicular stomatitis virus in > vitro - FEMS Microbiol Lett. 2015 > > - Control of small inhibitory RNA levels and RNA interference by doxycycline > induced activation of a minimal RNA polymerase III promoter - 2006 Nucleic > Acids Res. 34 > > - Inhibitory effect of doxycycline against dengue virus replication in vitro > - October 2013 Archives of Virology 159(4) > - Study of the antiviral activity of some derivatives of tetracycline and > non-steroid anti-inflammatory drugs towards dengue virus - August 2013 > Tropical Biomedicine 30(4):1-10 (BY THE WAY - DOXYCYCLINE IS A TETRACYCLINE) > > - A study of the clinical activity of a gel combining monocaprin and > doxycycline: a novel treatment for herpes labialis. (2012) J Oral Path Med > 41:61-67 > > > > The following paper was interesting in that it explored the role of > Doxycycline in inhibiting tumour cell proliferation, angiogenesis, metastasis > and migration of cancerous cells (including leukemic cells) from the bone > marrow: > > - Doxycycline inhibits leukemic cell migration via inhibition of matrix > metalloproteinases and phosphorylation of focal adhesion kinase - published > Molecular Medicine Reports, September 2015 Vol. 12, Issue 3. > > > Amani > > P.S. - By the way, Bob. The other thing that was featured in that show last > night about the fight against Ebola, is that the same doctor who contracted > it and was declared symptom-free, later began to develop eye problems and > when they examined his eye, they found millions of the Ebola viruses in the > eye. The programme explained that the eye was an area of reduced immunity in > the body, and thus, the virus had found a breeding ground where it remained, > though it had been cleared from the rest of the body. They therefore began > treating the doctor's eye, and the treatment was ultimately successful. It > brought to mind the problems Yogi had had with his eyes, and I wondered if > the answer was similar - that the virus had had a toe-hold there. > > > -----Original Message----- > From: Felvtalk > [mailto:[email protected]<mailto:[email protected]>] > On Behalf Of ROBERT CHAPEL > Sent: March-01-17 5:02 PM > To: [email protected]<mailto:[email protected]> > Cc: [email protected]<mailto:[email protected]> > Subject: Re: [Felvtalk] Knowing the " whys" of Win/Pred/Doxy > > Amani... > > If we consider the extended time frame for Doxy and multiple courses of other > ABX it makes a certain "intuitive" sense that a non bacterial infection is > going to require a longer period of time to have whatever non-specific ( > read... not related to bacterial infection necessarily)...? So little > research money appears to be devoted to FeLV that I don't know that we'll > know in the next decade unless the continuing demands of consumers ( who do > NOT want to hear , in this day and age of " Miracles") that there is _ no > hope_ for their much loved > pets) alter this course.??? I STILL bristle when I think of the closed minds > in the medical and Veterinary community and SO resent that businessmen( > Yes...that is what the vast majority are turning into now that practices are > being forced to consolidate into " Health Systems").. hold the power of life > and death over us AND our pets.?? On the plus side.... with the business > model being what it is ( and in contrast to the lost art of " > professionalism")? The CONSUMER is always right.? Vets will be forced, in the > future, to work more closely with the " customers" wishes as attachment to a > given vet will become less common as time goes on and people will " practice > shop " for the answers they want until such time as Vet services become so > expensive that insurance becomes a " must have " and ultimately go the way of > medicine ( ie...being confined to a slate of approved practitioners... > again....limiting choice)...? But... there are some years to go before that > happens and I feel that there IS a window of opportunity happening NOW and > for the next few? years for people to have some real influence on how Vets > practice....?? I am betting, for example, that had I had the money to go to a > more " well to do " neighborhood where people are more demanding and better > informed I could have found a vet to cooperate... Here in the "sticks" people > just blindly accept what the vet has to say and they still enjoy the freedom > of calling all the shots.....?? This WILL end over the next couple of years.? > I learned a lot with this first experience and made mistakes that I WILL NOT > make again. > > BTW....? Do you have any literature in support of the AntiRNA effects of > Doxy...???? I am SO happy that there are still a couple of things out there > that we still can get our hands on that don't have to pass muster with script > pad businessmen....? STILL I am also not advocating the the medically ill > prepared take it upon themselves to decide that THEY will decide what is best > for their animal... If we are going to go above and beyond our Vets advice it > would best be with very sound reasoning and an EXCELLENT understanding of > what we are doing and why.?? Anything less and the community of Veterinary > practitioners could easily dismiss our successes as "dumb luck" or ascribe > them to " unknown" factors.....? I think this is particularly important re: > Winstrol/Pred/Doxy?? I'd hate to see people going to their vets asking for > this combination of drugs and really having an inadequate understanding of > why they are asking for beyond the fact that it's been recommended on our > forum...??? For m > yself... I am clear on the Whys of Winstrol and Doxy ( though will be > looking for more lit support on the RNA effects of Doxy) but not clear on the > whys of the Pred. > Sorry for taking up so much space here but I'm having an " attack " of > missing my little guy and am tremulous about being caught in the same > position if I take in another FeLV as I am inclined to do.... > > > _______________________________________________ > Felvtalk mailing list > [email protected]<mailto:[email protected]> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > [email protected]<mailto:[email protected]> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 35, Issue 3 > *************************************** > > _______________________________________________ > Felvtalk mailing list > [email protected]<mailto:[email protected]> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org >
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