If you make a T1 map you can use that to look at differences in myelin content, but I don't know all of the ways to calculate T1 or if you could get that from only two flip angles. Two images with roughly the same contrast won't work for the ratio method. You need to have opposite contrast.
Also I'm not sure how a FLAIR would be better than a T2-SPACE. Peace, Matt. From: Satrajit Ghosh <sa...@mit.edu> Date: Tuesday, November 20, 2012 5:51 PM To: Matt Glasser <m...@ma-tea.com> Cc: "Watson, Christopher" <christopher.wat...@childrens.harvard.edu>, "Winter, Warren" <warren.win...@childrens.harvard.edu>, "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu> Subject: Re: [Freesurfer] Tool for incorporating T2-SPACE data in pial surface recons? hi matt: could you generate the myelin maps say from two flash scans at different flip angles? bruce: if one had a choice between an mprage + t2 flair and 2 flash scans at 5/20 flip angles, what would be your recommendation? cheers, satra On Tue, Nov 20, 2012 at 6:35 PM, Matt Glasser <m...@ma-tea.com> wrote: > If you get an MPRAGE and T2-SPACE you can make myelin maps too. > FreeSurfer's final surface placement benefits a lot from high resolution > images (less than 1mm) and you can still get good SNR with when you use > 32-channel coils. > > Peace, > > Matt. > > On 11/20/12 4:41 PM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote: > >> >Yes, definitely. The t2-space flair is a big help >> > >> > >> > >> >On Nov 20, 2012, at 5:40 PM, "Watson, Christopher" >> ><christopher.wat...@childrens.harvard.edu> wrote: >> > >>> >> Hi Bruce, >>> >> So would you recommend acquiring a T2 in addition to an >>> >>(ME)MPRAGE/SPGR? i.e. is it worth squeezing another acquisition into a >>> >>protocol? >>> >> >>> >> Chris >>> >> ________________________________________ >>> >> From: freesurfer-boun...@nmr.mgh.harvard.edu >>> >>[freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Bruce Fischl >>> >>[fis...@nmr.mgh.harvard.edu] >>> >> Sent: Tuesday, November 20, 2012 3:01 PM >>> >> To: Winter, Warren >>> >> Cc: freesurfer@nmr.mgh.harvard.edu >>> >> Subject: Re: [Freesurfer] Tool for incorporating T2-SPACE data in pial >>> >>surface recons? >>> >> >>> >> Hi Warren >>> >> >>> >> yes, it will be part of the upcoming 5.2 release, hopefully in Dec. It >>> >> will use either a FLAIR or T2 (ideally T2-SPACE for either one) >>> >> >>> >> cheers >>> >> Bruce >>> >> On Tue, 20 >>> >> Nov 2012, Winter, Warren wrote: >>> >> >>>> >>> Hi all, >>>> >>> >>>> >>> Back in January and October Bruce mentioned that he had under >>>> >>>development some scripts designed to utilize T2-SPACE images for better >>>> >>>pial surface reconstruction in the presence of dura -- I was just >>>> >>>wondering if any of that is ready for trial? >>>> >>> >>>> >>> Thanks! >>>> >>> >>>> >>> Warren >>>> >>> >>>> >>> -- >>>> >>> Warren Winter >>>> >>> Research Coordinator >>>> >>> Boston Children's Hospital >>>> >>> Sheridan Laboratory of Cognitive Neuroscience >>>> >>> Division of Developmental Medicine >>>> >>> 1 Autumn Street, AU 650 >>>> >>> Boston, MA 02215 >>>> >>> 857-218-5224 >>>> >>> >>>> >>> >>>> >>> _______________________________________________ >>>> >>> Freesurfer mailing list >>>> >>> Freesurfer@nmr.mgh.harvard.edu >>>> >>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >>>> >>> >>>> >>> >>>> >>> >>> >> _______________________________________________ >>> >> Freesurfer mailing list >>> >> Freesurfer@nmr.mgh.harvard.edu >>> >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >>> >> >>> >> >>> >> The information in this e-mail is intended only for the person to whom >>> >>it is >>> >> addressed. If you believe this e-mail was sent to you in error and the >>> >>e-mail >>> >> contains patient information, please contact the Partners Compliance >>> >>HelpLine at >>> >> http://www.partners.org/complianceline . If the e-mail was sent to you >>> >>in error >>> >> but does not contain patient information, please contact the sender and >>> >>properly >>> >> dispose of the e-mail. >>> >> >>> >> >>> >> >> > >> >_______________________________________________ >> >Freesurfer mailing list >> >Freesurfer@nmr.mgh.harvard.edu >> >https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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