You would do the long analysis using a random effects analysis. For each subject you can get a slope (this won't work if the subject only has 1 time point), then concatenate the slopes into a file and run mri_glmfit, then follow the procedures from the archive email you reference. doug
On 02/24/2015 08:35 PM, Janosch Linkersdörfer wrote: > Hi Doug and others, > > I would like apply (Monte Carlo simulation) cluster correction (as opposed to > the implemented vertex-wise FDR correction) on the results from a > longitudinal study I analyzed using the LME toolbox. The design is unbalanced > (different number of time points, from 1 to 4, per subject). > > In this thread > (http://www.mail-archive.com/freesurfer%40nmr.mgh.harvard.edu/msg35367.html) > you, Doug, suggested, if I understand correctly: > > - concatenating the images using `mris_preproc --paired-diff` > - smooth with the same kernel size as used in the lme analysis > - running `mri_glmfit` on them with an fsgd file that uses the same > covariates and the same contrast (excluding the interaction term with time) > as used in the lme analysis > - overwriting sig.mgh with the one from the lme analysis > - running `mri_glmfit-sim --cache` > > How would I extend this to my case where I don't have pairwise images, but 1 > image for some participants, for others up to 4? > > Thanks a lot, > > Janosch > > > > -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
