Hi Doug, thank you very much for your answer!
Am 02.03.2015 um 11:30 schrieb Douglas N Greve <gr...@nmr.mgh.harvard.edu>: > > You would do the long analysis using a random effects analysis. OK, so basically do 2-stage modeling (https://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalTwoStageModel), right? > For each subject you can get a slope (this won't work if the subject only has > 1 time point), then concatenate the slopes into a file and run mri_glmfit, > then follow the procedures from the archive email you reference. One quarter of my subjects only has one measurement time point. Can I still use this method (which would only consider the 3/4 of the subjects) to correct clusters found in the whole group? Or would it only be valid for correcting clusters from an LME model for the reduced group? Thanks, Janosch > doug > > On 02/24/2015 08:35 PM, Janosch Linkersdörfer wrote: >> Hi Doug and others, >> >> I would like apply (Monte Carlo simulation) cluster correction (as opposed >> to the implemented vertex-wise FDR correction) on the results from a >> longitudinal study I analyzed using the LME toolbox. The design is >> unbalanced (different number of time points, from 1 to 4, per subject). >> >> In this thread >> (http://www.mail-archive.com/freesurfer%40nmr.mgh.harvard.edu/msg35367.html) >> you, Doug, suggested, if I understand correctly: >> >> - concatenating the images using `mris_preproc --paired-diff` >> - smooth with the same kernel size as used in the lme analysis >> - running `mri_glmfit` on them with an fsgd file that uses the same >> covariates and the same contrast (excluding the interaction term with time) >> as used in the lme analysis >> - overwriting sig.mgh with the one from the lme analysis >> - running `mri_glmfit-sim --cache` >> >> How would I extend this to my case where I don't have pairwise images, but 1 >> image for some participants, for others up to 4? >> >> Thanks a lot, >> >> Janosch >> >> >> >> > > -- > Douglas N. Greve, Ph.D. > MGH-NMR Center > gr...@nmr.mgh.harvard.edu > Phone Number: 617-724-2358 > Fax: 617-726-7422 > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 > www.nmr.mgh.harvard.edu/facility/filedrop/index.html > Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ > > > > The information in this e-mail is intended only for the person to whom it is > addressed. If you believe this e-mail was sent to you in error and the e-mail > contains patient information, please contact the Partners Compliance HelpLine > at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
