Thank you Doug. So, instead of running mri_surfcluster I should run 
mri_glmfit-sim with the --fwhm-override with the smoothing obtained from 
the residuals of the lme model.

Thanks again,

A 2017-07-18 22:09, Douglas N Greve escrigué:
> Not sure. It might be more accurate. Once you have the FWHM you want,
> you can run mri_glmfit-sim with --fwhm-override
> 
> 
> On 07/17/2017 05:43 PM, Jordi Pegueroles wrote:
>> Dear FS experts,
>> 
>> I was wondering if someone had performed multiple comparisons (ie 
>> monte-carlo) with the LME analyses. I have found a thread 
>> (https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg40195.html) 
>> where Doug recommends to run a GLM fit with the same data and then 
>> overwrite the sig.mgh file with the LME one.
>> 
>> My question is if is not more accurate to estimate the residuals from 
>> the LME model, then compute the relative smooth of the data with the 
>> mris_fwhm command and pass it as an argument in the mri_surfcluster 
>> command (mri_surfcluster --in $direct1/sig.mgh --csd 
>> /Applications/freesurfer/average/mult-comp-cor/fsaverage/${hemi}/cortex/fwhm${rfwhm}/abs/th13/mc-z.csd
>>  
>> --cwsig $direct1/mc.abs.th13.sig.cluster.mgh --vwsig 
>> $direct1/abs.th13.sig.vertex.mgh --cwpvalthresh 0.05 --surf white).
>> 
>> Thanks in advance.
>> 
> 
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
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