The PET signal can change with a lot of anatomical changes in the brain including thickness, surface area, and gyrification. There is no known regressor that will account for this. Right right way to account for it is with partial volume correction (PVC). It is best to do PVC simultaneously with the recon, but software is not available to perform this. You can do it on a post-hoc basis in PETsurfer using the PVC options in mri_gtmpvc. See the wiki.
On 08/10/2017 04:11 AM, John Anderson wrote: > > Hi Dr Greve, > > I have PET data for two groups and I used PET surfer in FSV 6.0 to run > the analyses. The pipeline is straightforward and the analysis ran > smoothly without any issues. > > Is it correct procedure to adjust PET signal to differences in gray > matter volume or cortical thinness between two groups? > > In other words, is it correct if gray matter volume or cortical > thickness for subjects be included as EVs in GLM or a nausiance factor > in QDEC? > > Specifically, is the PET signal changeable depending on differences > in cortical thickness. > or differences in gray matter volume? > > Thank you for any clarification > >> Thank you ! >> Jon >> > > > > _______________________________________________ > Freesurfer mailing list > [email protected] > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center [email protected] Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list [email protected] https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
