On 1/21/14, 5:29 PM, glen wrote:
Are there some cells, in the same cancer, that are more (or less) metastatic than other cells in that same cancer?
I seem to recall one hypothesis was that stem cells were suspect in cancer in part because they tend to resist chemotherapy. And that one benefit of developmental specialization of cells was to be resistant to that kind of corruption. I don't think it is the case that tumors are heterogeneous.

http://www.nature.com/nature/journal/v501/n7467/full/nature12624.html

Marcus

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