Hello,

We are not sure which method you are using to do your large batch 
queries. If downloading files using your web browser from our downloads 
area, it will complain about very large files as you describe.

Instead, I would recommend direct ftp to download entire chromosomes or 
database files/tables. Then using our tools or yours to subset the data 
as necessary. If you are not a unix user, the Table browser is a good 
option. Instructions for both methods are in this FAQ:
http://genome.ucsc.edu/FAQ/FAQdownloads#download32

If this does not help, please let us know. In your reply, please include 
the specifics of the process (download method, genome/version, file 
names, etc) that you have questions about and we can provide more help,
Thank you,
Jennifer Jackson
UCSC Genome Bioinformatics Group

Edouard Henrion wrote:
> Hi,
>
> I am making quite large batch queries to retrieve genomic DNA sequence 
> from UCSC website.
> My browser just displayed a message telling me that I should inquire 
> about more efficient ways to access your data.
> Could you please inform me about these better ways ?
>
> Thanks a lot !
>
> Édouard
>
>   
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