I found this message in the archive, and joined the list. I have the same
problem exactly: my tablet works, but the mouse is ignored when it's on the
canvas area (only).
I found a workaround: In Preferences-->Input Devices, reset settings to
defaults. Restart GIMP like it tells you to. Then, in the same place,
configure the extended devices again (In my case, set Mouse, , and 
from "Disabled" to "Screen".) That fixes it for a while, but not permanently.
I will file a bug report if I can figure out what makes it break, too.
Gimp 2.2.13, Linux kernel 2.6.18, Xorg 7.2 RC2, 64 bit openSUSE 10.2, Wacom
Graphire 3 tablet
>Wed, 20 Dec 2006 07:23:55 -0800
>Hello. Some time ago, the Gimp stopped responding to my mouse in the image
>window. In other windows and on menus the mouse works fine (ie I can select
>brushes and such and use the interface without problems), but in the image
>window (or more precicely, the canvas area) it's as if the mouse doesn't even
>exist. All kinds of clicks are ignored, the rulers doesn't show the position
>of the cursor, and the position in the lower left also isn't updated (it is
>set once upon entering the window, but after that it's dead). My tablet
>still works fine, but not being able to use the mouse for anything is
>This originally happened out of the blue one day while using Gimp 2.2.11 (I
>unfortunately have no idea what caused this to happen). I tried upgrading to
>2.2.12 and then 2.3.13, without success. I also deleted the ~/.gimp*
>directory in the hope that regenerating the config would fix the problem, but
>no. No matter what I do, I can't make the Gimp recognize the mouse in the
>image window. The mouse isn't anything special, and it used to work with the
>exact same X config I've got now. I haven't changed the xorg.conf file in
>several months. The Gimp is the only application with this problem.
>This is on a dual-core amd64 processor in 64-bit mode (haven't tried 32-bit),
>Linux kernel 2.6.18, Xorg 7.1.
>Does anyone know what might be causing this, and how to fix it ?
Gimp-user mailing list