Dear Sir or Madam,
I am new to the neuroimaging, and now I have a question about defining a
spherical seed region for the seed-based functional connectivity.
My question is:
If a seed region has a radius of 4 mm and is centered at MNI coordinates
(0,-53,26), and the voxel is 2-mm isotropic, what is the routine to
determine which voxels are in the spherical region? If >50% of a voxel was
within the spherical region, would you think the voxel is effectively in
the region, i.e., would you take the voxel into account to calculate the
averaged time series of the seed region?
Btw, is there any software or Matlab package (preferred) to draw the
spherical region and tell you the voxels in the region?

Thanks.

Best,
Harry

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