Dear Experts:

We have acquired rfMRI dataset with A-P and P-A phase encoding direction and 
the data was acquired in eight 5-minute runs split across four imaging 
sessions. We have processed the data using HCP pipelines (e.g., PreFreeSurfer, 
FreeSurfer, PostFreeSurfer, fMRIVolume, fMRISurface and ICA+FIX). So we have 
results for each run of rfMRI data. 

I’m just curious about what is recommended way to combine each run of data 
(e.g., rfMRI_REST1_AP, rfMRI_REST1_PA, …, rfMRI_REST4_AP, rfMRI_REST4_PA). 

Can we just temporally concatenate each run of data before running ICA+FIX?
Or can we do group ICA using each data processed with ICA+FIX?
What is the optimal way to do combining analysis across each run? 

Any insights would be greatly appreciated. 

Thanks. 

Sang-Young Kim
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Postdoctoral Research Fellow
Department of Radiology at University of Pittsburgh
email: [email protected]
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