Thanks! Matt!

I have one more following-up question. In order to run the script 
"hcp_fix_multi_run", we have to concatenate all the data temporally, right?
I combined the data using following command: fslmerge -t <rfMRI_REST_Concat> 
<rfMRI_REST1_AP> …<rfMRI_REST4_PA>. 

Then, I ran the hcp_fix_multi_run script as follow: hcp_fix_multi_run 
<rfMRI_REST_Concat.nii.gz> 2000 rfMRI_REST_Concat 
${FSL_FIXDIR}/training_files/HCP_hp2000.RData
I also tried to input the data as a list file, but the script didn’t work with 
error. It seems to get only one 4D rfMRI data set as input. 
That’s why I concatenated each run of rfMRI data set. 

Could you please confirm whether the above procedures are correct or not?

Thanks again. 

Sang-Young
 

> On Oct 6, 2017, at 3:57 PM, Glasser, Matthew <[email protected]> wrote:
> 
> I would not do #2 as you need to do some preprocessing prior to running 
> ICA+FIX when concatenating across runs and this is all that the multi-run 
> ICA+FIX pipeline does differently from regular ICA+FIX.
> 
> I’ll let Steve answer that other question.
> 
> Matt.
> 
> From: Sang-Young Kim <[email protected] <mailto:[email protected]>>
> Date: Friday, October 6, 2017 at 11:06 AM
> To: Matt Glasser <[email protected] <mailto:[email protected]>>, Stephen 
> Smith <[email protected] <mailto:[email protected]>>
> Cc: "[email protected] <mailto:[email protected]>" 
> <[email protected] <mailto:[email protected]>>
> Subject: Re: [HCP-Users] Combining rfMRI data for different phase encoding 
> directions
> 
> Hi, Matt and Stephen:
> 
> Thanks for your responses. So I will try below three options to see which one 
> is better. 
> 
> 1. ICA+FIX on each 5 min run separately 
> 2. Concatenate each pair of scans from each session and then ICA+FIX on each 
> session
> 3. Use multi-run ICA+FIX to combine across runs
> 
> I have another simple question. In the paper published in NeuroImage (Smith 
> et al., 2013, rfMRI in the HCP), the Figure 9 shows functional connectivity 
> in the default mode network; one is from 15 min run from single subject, 
> another one is from 4*15 min runs from single subject, and the other one is 
> from all subjects concatenated. 
> 
> How did you process the data to present those figures (second and third one)?
> The third one should be processed with group ICA, right? 
> What about the second one? This is processed with method 3 on above list?
> 
> Thanks. 
> 
> Sang-Young
>   
> 
>> On Oct 6, 2017, at 5:40 AM, Glasser, Matthew <[email protected] 
>> <mailto:[email protected]>> wrote:
>> 
>> There is a beta version of a multi-run ICA+FIX pipeline available in the HCP 
>> Pipeline’s repository.  For 5 minute runs, I would expect combining across 
>> runs to be best.  We haven’t tested combining across sessions yet, so you 
>> would have to check that that was working okay if you wanted to try that.
>> 
>> Peace,
>> 
>> Matt.
>> 
>> From: <[email protected] 
>> <mailto:[email protected]>> on behalf of Stephen Smith 
>> <[email protected] <mailto:[email protected]>>
>> Date: Friday, October 6, 2017 at 1:49 AM
>> To: Sang-Young Kim <[email protected] <mailto:[email protected]>>
>> Cc: "[email protected] <mailto:[email protected]>" 
>> <[email protected] <mailto:[email protected]>>
>> Subject: Re: [HCP-Users] Combining rfMRI data for different phase encoding 
>> directions
>> 
>> Hi - I think your main two choices are whether to run FIX on each 5min run 
>> separately, or to preprocess and concatenate each pair of scans from each 
>> session and run FIX for each of the 4 paired datasets.  You could try FIX 
>> both ways on a few subjects and decide which is working better.
>> 
>> Cheers.
>> 
>> 
>> 
>>> On 5 Oct 2017, at 22:53, Sang-Young Kim <[email protected] 
>>> <mailto:[email protected]>> wrote:
>>> 
>>> Dear Experts:
>>> 
>>> We have acquired rfMRI dataset with A-P and P-A phase encoding direction 
>>> and the data was acquired in eight 5-minute runs split across four imaging 
>>> sessions. We have processed the data using HCP pipelines (e.g., 
>>> PreFreeSurfer, FreeSurfer, PostFreeSurfer, fMRIVolume, fMRISurface and 
>>> ICA+FIX). So we have results for each run of rfMRI data. 
>>> 
>>> I’m just curious about what is recommended way to combine each run of data 
>>> (e.g., rfMRI_REST1_AP, rfMRI_REST1_PA, …, rfMRI_REST4_AP, rfMRI_REST4_PA). 
>>> 
>>> Can we just temporally concatenate each run of data before running ICA+FIX?
>>> Or can we do group ICA using each data processed with ICA+FIX?
>>> What is the optimal way to do combining analysis across each run? 
>>> 
>>> Any insights would be greatly appreciated. 
>>> 
>>> Thanks. 
>>> 
>>> Sang-Young Kim
>>> ***********************************************************
>>> Postdoctoral Research Fellow
>>> Department of Radiology at University of Pittsburgh
>>> email: [email protected] <mailto:[email protected]>
>>> ***********************************************************  
>>> 
>>> 
>>> _______________________________________________
>>> HCP-Users mailing list
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>>> <http://lists.humanconnectome.org/mailman/listinfo/hcp-users>
>> 
>> 
>> ---------------------------------------------------------------------------
>> Stephen M. Smith, Professor of Biomedical Engineering
>> Head of Analysis,  Oxford University FMRIB Centre
>> 
>> FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
>> +44 (0) 1865 222726  (fax 222717)
>> [email protected] <mailto:[email protected]>    
>> http://www.fmrib.ox.ac.uk/~steve <http://www.fmrib.ox.ac.uk/~steve>
>> ---------------------------------------------------------------------------
>> 
>> Stop the cultural destruction of Tibet <http://smithinks.net/>
>> 
>> 
>> 
>> 
>> 
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