Dk,
  Finally, something we agree on :-))
Jay

-----Original Message-----
From: [email protected] 
[mailto:[email protected]] On Behalf Of DK
Sent: Thursday, January 05, 2012 11:25 AM
To: [email protected]
Subject: Re: 10X PBS

In article <[email protected]>, Joshua Silverstein 
<[email protected]> wrote:
>You don't need physical chemistry, just general.
>
>If you take 10X PBS and dilute it with deionized water, it will certainly
>change the pH.  For a 10-fold dilution, it should change the pH by
>approximately 1 (log scale).

False. We are talking about buffers here... 

DK



>
>
>On Wed, Jan 4, 2012 at 3:38 PM, DK <[email protected]> wrote:
>
>> In article <[email protected]>, "Jayakumar,
>> R" <[email protected]> wrote:
>> >Ideally the pH should not change much between 10X and 1X if deionised
>> water was
>> > used for dilution.  Presnce of NaCl has nothing to do with pH changes
>> since it
>> > contributes neither hydroxyl nor hydrogen ions
>>
>> You need to refresh your physical chemistry.
>> (Hint: cations compete with protons for binding to anions)
>>
>> DK
>>
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