Hi Dan,

Thanks for that. I hadn't heard of CWD in natural populations of deer
and elk. I learn something new every day.

A bit casual of you to suggest equating it with mad cow - BSE and
HVCJD - and over 50% population, but you're right these are a scary
class of diseases.  Natural mutations of proteins to prion - virus
like - fragments that make them transmissible even if their original
arising, their disease causing effects and their transmissibility are
relatively rare and random.

I won't say any more until I know a little more about it, but I
suspect this is a balance of risks question - the risk of alternatives
to the original risk .... but no point taking a risk there is no need
to take, as you say.
Thanks again.
Ian

On 2/13/07, Dan Glover <[EMAIL PROTECTED]> wrote:
> >From: "ian glendinning" <[EMAIL PROTECTED]>
> >Reply-To: [email protected]
> >To: [email protected]
> >Subject: Re: [MD] dualism
> >Date: Mon, 12 Feb 2007 17:04:14 -0600
> >
> >Dan, you said
> >"Here a good percentage (well over half) of deer are infected with prion
> >disease (mad cow) ..."
> >
> >Huh ? what ? how ?
> >I sincerely doubt it. I'm hard pushed to think of any possible mechanism.
> >Do you have any evidence or reference to that remark ?
> >(Or are we just talking the generic concept of a prion disease, and if
> >so in what sense are we using the word "infected" ?)
>
> Hi Ian
>
> You may (or may not) know that "mad cow" disease (bovine spongiform
> encephalopathy) and the human variant (Creutzfeldt-Jakob disease) are both
> (possibly) related to chronic wasting disease (CWD) in deer and elk. These
> as a group are known as transmissible spongiform encephalopathy. It is
> speculated that these diseases are the result of an infectious agent made of
> mis-folded protein or a prion (short for proteinaceous infectious particle).
>
> This came from a study done in 2002:
>
> "Wildlife disease experts concluded that in the absence of management
> intervention, CWD will most likely increase in prevalence and distribution.
> There is no evidence that CWD will "burn itself out" if left alone. Further
> there is no evidence of genetic resistance to CWD in white-tailed deer or
> mule deer. A simulation model suggests that if left unmanaged CWD will
> spread widely throughout Wisconsin and will substantially increase in
> prevalence to more than 40 percent of adult deer. The model simulations are
> consistent with recent findings from Colorado that have shown increases in
> prevalence over the past few years in numerous local populations. Prevalence
> on some of their local winter ranges now exceeds 25-30 percent. To put this
> in perspective, in some sections of Wisconsin's core area prevalence is as
> high as 8-12 percent. In addition, the known affected area in both Colorado
> and Wyoming has expanded to the west and northwest more than 100 miles
> during the past five years."
>
> Since then the situation has (supposedly) grown progressively worse. The
> disease appears to be spread by animal to animal contact via saliva and
> other bodily fluids.
>
> I don't eat deer or elk meat so I have no worries but when I saw SA mention
> he planned on harvesting some meat I just threw it out there. Actually I've
> read some newspaper articles recently that claimed the "over 50%" figure I
> gave but that may or may not be correct. I'm not sure any definitive studies
> have been done on the wild deer and elk population.
>
> Better safe than sorry though, right? For more information just Google prion
> or chronic wasting disease and you'll find much info.
>
> Thank you for your comments,
>
> Dan
>
>
>
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