Thanks again everyone, this has been very useful. I will start 
testing/comparing methods next week, and will likely get back to some of 
you if I run into questions.
Best! Christy

On Friday, February 24, 2023 at 3:46:42 AM UTC+1 Vera Weisbecker wrote:

> Hi Christy, 
>
>  
>
> I have used endomaker a bit for birds and it has been a revelation, it 
> takes seconds to create pretty good endocasts that need a little bit of 
> fixing in something like geomagic. If I had to do mammals now on the normal 
> endomaker package, I would work out the fastest way of  cropping off all 
> the bone that isn’t related to surrounding the brain, then wrap the outside 
> skull/close off the foramen magnum, and run endomaker. It would still be 
> way faster than manual segmentation. 
>
>  
>
> Cheers,
>
>  
>
> Vera
>
>  
>
> *From:* [email protected] <[email protected]> *On Behalf Of 
> *Paul Penkalski
> *Sent:* Friday, 24 February 2023 7:09 AM
> *To:* Christy Hipsley <[email protected]>
> *Cc:* Morphmet <[email protected]>
> *Subject:* Re: [MORPHMET2] programs for generating cranial endocasts
>
>  
>
> Hi Christy,
> Another good option is ITK-SNAP: http://www.itksnap.org/
>
> Although it isn't designed specifically to segment endocraniums, it
> has several automatic algorithms that I've used to segment fossil
> braincases automatically and it worked really well. You may have to
> clean up the segmentation a little at the end, but that's true for any
> program. Then you can save the segmentation as a 3D model or mesh.
>
> You might download it and do a quick test segmentation, and you'll see
> how straighforward it is. I had tried 3D Slicer prior to that and
> couldn't get it to do anything useful. Then someone recommended
> ITK-SNAP. Of course there are a few commercial apps too, but they
> aren't any easier to use, and not really any more powerful than ITK,
> and obviously more expensive.
>
> Downsampling the scan is a good idea. I often do that. You can also
> crop it, e.g. if it's a scan of the whole skull and you only need to
> segment the endocranium. I like IrfanView which can do batch crop and
> resize and has a DICOM plugin (and it's free, at least the older
> versions). 0.1 mm is pretty high resolution unless you're scanning
> mice!
>
> Cheers,
> Paul P.
>
>
> On 2/23/23, Murat Maga <[email protected]> wrote:
> > Without the data it is hard to tell, but often those crashes are memory
> > related. Memory usage during segmentation increases 8-10 folds based on 
> the
> > segmentation effect being used. So if your dataset is 2GB, you need 
> minimum
> > of 16-20GB of "available" RAM for Slicer to work properly. If you can 
> share
> > your dataset, I can take a look.
> >
> > Also for endocast segmentation there is no need to work with full
> > resolution images. You can downsample your image (via the CropVolume) by 
> 2,
> > and then try. That will reduce your data volume by 8 folds. Your
> > experiments will go faster too.
> >
> > The other important parameters is the size of the largest hole to plug, 
> and
> > the smoothing. Default parameters we included worked fine for large apes,
> > but I am not sure for seal skulls.
> >
> >
> >
> > On Thursday, February 23, 2023 at 7:24:30 AM UTC-8 Christy Hipsley wrote:
>
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