> What would the reason be to choose for a higher voltage rather than a
> lower anode resistor? You can achieve a higher tube current by either
> raising the voltage or lowering the resistor, so what is the advantage
> of raising the voltage? Is it because ionization will be quicker or
> doesn't have that anything to do with it?

Ionization will be quicker with a higher voltage.  Mike M. (threeneurons) 
actually went to the
trouble to measure the turn-on behaviour of a nixie:

http://threeneurons.files.wordpress.com/2011/08/timing01.jpg

I'm thinking of duplicating his setup and trying it with different anode 
voltages and a few
different nixies (I'm guessing little nixies ionize faster).  I may also try 
using a decimal point
as a "primer" and even comparing nixies with and without ambient light.

Another advantage of higher voltage is better current regulation - since more 
of the drop
is across the anode resistor and less across the (dynamic, negative, varies 
with the digit lit)
resistance of the nixie, the current for different digits will be more similar.

A disadvantage of higher voltage is lower efficiency - more of your voltage is 
used up in
the anode resistors as heat.  This can be combated by using a current-limited 
supply, which
can give wonderful efficiency but adds a good deal of complexity (current 
limiting a negative
resistance load which is being continually switched ain't easy).  
Alternatively, a scheme like
David uses in his watches (raising the voltage to strike, then lowering it) 
strikes a different
balance between ionization time, efficiency, and complexity.

Another disadvantage is the voltage impressed on the "off" cathodes if the 
anode voltage is
turned on but the digit is blanked.  This can lead to ghosting (especially if 
the transistors are
zener clamped or leak at high voltage) or failure of the cathode switches if 
they can't withstand
the voltage.  An obvious way to address this is don't enable the anode switch 
for blanked
digits, which requires a few wiring and/or software considerations, depending 
on the design.

- John

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