You may want to consider other topologies, such as flyback.

I spent a *LOT* of time debugging the DC-DC converter for my wristwatch 
project, with simulations and bench-testing. In the end, I got it working 
but my simulations were way-off because I did not have proper modeling of 
my transformer. 

The main problem I had was saturation, because I used such a small 
transformer due to space-constraints. Lesson-learned: Use an oversized 
inductor and stay well-away from Isat. You'll know it's saturating because 
it will get warm, and even warmer while under load. 

Another area you need to be careful about is the kick-back when the 
switching device shuts off. Depending upon the topology, your switch should 
be rated at the max output of your converter, NOT the DC input supply 
voltage. If you go with a flyback transformer (I used a 10:1 ratio), the 
kickback is *ideally* lowered by the turns ratio; in reality it's 
substantially higher due to leakage inductance and other factors.

Be mindful of the ESR of the capacitor you are using for output filtering. 
Simulators, such as LTspice, will display the RMS current of device (a very 
handy feature).

Expect to spend a lot of time on the bench with a scope. Monitoring the 
current thru the inductor/switch with a scope can be tricky, because noise 
will couple into the scope's ground lead and make you think you have 
horrible ringing/overshoot when you really dont. There are some good 
techniques online, such as removing your scope's ground lead and 
probe-shroud, and connecting the ground at the exposed metal ring near the 
probe tip.

Lastly, you will find that DC-DC converters work beautifully under almost 
no load. Once you start loading them down, they dont work *as* nicely, but 
they definitely *do* work. Welcome to the real world.....

Most importantly, when you do get it working, congratulate yourself on your 
accomplishment.

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