Current-regulators are very simple to implement: NPN transistor with 
emitter resistor. Though you can use NMOS devices, they have a Vgs(on) of 
several volts, so they need to be driven from a higher voltage, around 
+10V, otherwise minor variations in Vgs (it's temperature-dependent, and 
varies device-to-device) will cause unacceptable variations in current.

The current causes a voltage-drop across the emitter resistor, which gives 
the required negative feedback.

The current is set by  (Vsupply-0.7)/Isegment   . This assumes the beta of 
the transistor is "large", say > 40 and Vbe is 0.7V .
For example, if you have +3.3V driving logic, and you want 4mA segment 
current, the resistor would be about 650 ohms. I use a spreadsheet and 
factor-in resistor-tolerance, voltage-supply variation, and normalize to a 
standard resistor value to fine-tune the current.

In this example, if the supply were to increase 3% from 3.3V to 3.4V, the 
current would increase 4% to 4.15mA. The current is independent of the 
tube's voltage drop (unless your anode-supply voltage is very close to the 
tube's voltage-drop).

Now, compare this to an unregulated driver that runs at +180V. If your 
tube-voltage-drop is nominally 140V, a 10K resistor will give you 4mA. But 
if the tube ages, or you replace it with another one, and the voltage drop 
increases 4% to 145V, your current will drop 13% to 3.5mA which may be an 
undesirable reduction in brightness.

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