This from danyk.cz in regards to lifetime expectancy.

This is probably caused by the addition of mercury, which limits 
evaporation of the cathode material and cathode poisoning. The lifetime is 
still several times underestimated, it is a minimum guaranteed lifetime. 
With proper handling, of mercury-enriched nixie can serve without any 
problem more than 5 or even 10 years of continuous operation. Especially if 
all of the cathodes are used evenly and sufficiently often alternated. When 
used in clocks it is therefore possible to achieve greater durability, 
particularly in frequently changing digits (seconds), than in the nixie 
measurement equipment, where most of the time, when they're not active, 
showed all zeros.

Dolam LC-516 contain mercury so you can expect a reasonable lifetime from 
them for your clock if you use them. I have had IN-1 tubes fail in a few 
weeks while others have ran for a couple of years. As with all tubes there 
are good production runs and there are bad production runs, it is a case of 
suck it and see. With technology from the 70s and 80s you cannot expect a 
cast iron guarantee for performance.

The brightest tubes I have in clocks are Z566Ms and a set of the hens teeth 
 ITT GNP-7AHs. After saying that, the set up of a tube is what will give 
the optimum in performance and longevity. Correct voltage and current will 
always get the best out of any tube, that is why we have data sheets from 
the manufacturers to assist us in design and circuitry.

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