We are in the process of evaluating a few of the vendors in this area. 
Specifically:

NetIQ AppManager
IBM Tivoli Monitoring (ITM)
HP Operations Manager
SCOM 2007

A lot of the functionality you need will affect what you get. For example, we 
need something that will connect to our ticketing system (IBM Tivoli Enterprise 
Console). We need the ability to monitor UNIX and Linux, etc.... Personally I 
like HP Operations Manager and SCOM 2007. I've already stood up a small 
instance of SCOM for KMS reporting. But HP Operations Manager is pretty 
impressive in this category. Seems to really do Linux, UNIX well and the 
connectors are decent. 

YMMV

chris
~ Finally, powerful endpoint security that ISN'T a resource hog! ~
~ <http://www.sunbeltsoftware.com/Business/VIPRE-Enterprise/>  ~

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