DOSBox (www.dosbox.com) is an x86 emulator with DOS. It works great for programming those radios that need old, slow PCs for the software. I use it on my MacBook dual booting into Windows 7 and using an IO Gear USB serial dongle on COM1. So far I've programmed a couple of Radius M1225's and a VXR-5000. A friend of mine has similar results with Windows XP on a 800Mhz PC with a real serial port.
-- Tim
