Zimbra exploded onto the scene sometime last year.  Their AJAX stuff is 
*very* slick.  The downsides are that their platform has a huge footprint 
(it carries with it all of the programs which most of the "rollup" open 
source groupware systems use for smtp/imap/etc. plus an entire JVM and an 
entire copy of MySQL), and a lot of the people who have tried it have said 
that it has the responsiveness you'd expect from a Java application.  
   
 They've definitely nailed the UI from a visual perspective, though.  It's 
a good example of where you can go if you have the opportunity to build 
using AJAX from the ground up, if you don't have an existing system to 
retrofit.  
   
 What I find curious about Zimbra as a business is that they seem more 
interested in finding investors and partners than in finding actual users 
right now.  
  

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