Re: [MBZ] OT - Replication errors

2007-05-24 Thread Rich Thomas
My dim brain power says to watch Blade Runner to see what could come 
of this.


--R

Redghost wrote:

J

Off the wall, but I am sure there is enough brain power on the list  
to at least shine a very dim light on the topic



  





Re: [MBZ] OT - Replication errors

2007-05-24 Thread Redghost

Hmmm.

So there are errors right off the bat?  That can not be good.  Well,  
I guess there are standard errors and deviations that do not really  
create damage in standard reproduction, so it should be fine for some  
errors in replication.


Maybe it was the point at which the deviations from a norm  
specification were induced that I was trying to see.  What would have  
the least probability of producing terminal errors and maintaining as  
close to original specifications?  Not that it matters if I am just  
going to be outsourced to a turkey baster anyway.


clay


On May 23, 2007, at 5:49 AM, Tony Wirtel wrote:



Just screwing around with an old ipod trying to make sure it would
work for my 6 year old to listen to.  Got one of those off the wall
thoughts pop in to my empty head

What would the replication errors be, or would there be, if a woman
were to carry her own clone?  How many generations hence before
errors would be induced if you used the original donor in succeeding
generation vs. donation from prior generation to source the next?

Off the wall, but I am sure there is enough brain power on the list
to at least shine a very dim light on the topic

--
Clay
Seattle Bioburner


Clay:

Not an expert, but there are ALWAYS replication errors; what changes
are the quantity.  After that I believe its simply a matter of
statistics of error probability taking over.  To VERY broadly
generalize if you're error rate is 1%, over 10 generations the
probability of success would be about 90%; if error rate is 99.9%,
then over the same 10 generations you'd be at about 99%. This assumes
much, perhaps the most important factor being that the error rate
would not change.

That said, with advances in science and medicine as well as cars that
are more reliable while also increasingly DIY unfriendly men are
pretty much SOL, anyway (grin).

Tony Wirtel

___
http://www.okiebenz.com
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Re: [MBZ] OT - Replication errors

2007-05-24 Thread Redghost

Um, babes ain't bananas, but I catch the drift.

I was thinking along the lines of not using the original source  
material but once or twice, and then allowing the use of progeny as  
source matter, so that any errors in duplication would evolve as the  
line continued.  AT some point there would be a self termination  
error induced, but at what point?  I am sure external forces would  
impact the viability of the line quickly, but would the line self- 
destruct before that happens?


clay

On May 23, 2007, at 8:08 AM, Ed Booher wrote:


On 5/22/07, Redghost [EMAIL PROTECTED] wrote:

What would the replication errors be, or would there be, if a woman
were to carry her own clone?  How many generations hence before
errors would be induced if you used the original donor in succeeding
generation vs. donation from prior generation to source the next?

Off the wall, but I am sure there is enough brain power on the list
to at least shine a very dim light on the topic


Well, the largest problem you run into first is that the process of
cloning is not exact as of yet. Too many errors are still introduced
merely by man trying to meddle in a natural process. So at this time,
you'd have genetic errors in the first generation. Now, supposing that
man ever gets to a point where genetic clones of humans are a 100%
reliable possibility, then you get into an even different problem. The
clone being a duplicate representation of the mother carrying the
child, the mother's body would be unable to tell any difference
between the child and the mother. Meaning any disease, cancer, etc
that the mother may have/contract during the 9 month incubation would
have a far larger risk of being transferred to the clone child as the
genetics involved can not tell a difference and begin to rewrite the
clone DNA with the same RNA rewriting the mothers.

Further, look at the plight of the banana. Some 65 or so years ago
(roughly, going by memory instead of taking research time to pull
proper data) there was a banana that was known as the Big Mike. People
that still remember the Mike say that it was a firmer, sweeter banana
than we have today. Heck, some of the listers may remember the Big
Mike. Every banana that we eat today, that we think of as the
banana, the bright yellow color, the curvature, the God inspired
easy open handle is a clone. They are all genetically identical. So
was the Big Mike, it too was a genetic clone. Every Mike was the same
on the cellular level. Today, you will not find a Mike. Period. They
are extinct.

A disease ran rampant through the Mike. It spread, eventually, to
every banana field in the world that grew the Mike. Because they were
cloned, there was no genetic alterations, no differences, that allowed
any strain of MIke to become impervious to the disease, and as such,
every last one was wiped out. Today, the same has started occuring to
the Cavendish Banana (the bright yellow, etc) and there may be one day
soon that we have to start eating a completely different banana again.
As the last of the Cavendish becomes extinct.

A perfect human clone would face the same fate after 20 or so
generations. There wouldn't be enough genetic differences left in the
gene pool to combat all diseases and the race would slowly die out.
Probably.

--
Knowledge is power... Power Corrupts. Study hard... Be Evil.

___
http://www.okiebenz.com
For new parts see official list sponsor: http://www.buymbparts.com/
For used parts email [EMAIL PROTECTED]

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Re: [MBZ] OT - Replication errors

2007-05-24 Thread Redghost
I think Blade Runner was dealing with androids not clones.  The  
company had made psuedo people that were closer to human and had to  
have self limiting systems engineered into them so as not to upset  
the locals.  Then the gummint got involved and it just went down  
hill.  Sean Young sure was a hotty in that flick.  Too bad she lost  
her mind and .



clay

On May 23, 2007, at 4:50 PM, Rich Thomas wrote:


My dim brain power says to watch Blade Runner to see what could come
of this.

--R

Redghost wrote:

J

Off the wall, but I am sure there is enough brain power on the list
to at least shine a very dim light on the topic






___
http://www.okiebenz.com
For new parts see official list sponsor: http://www.buymbparts.com/
For used parts email [EMAIL PROTECTED]

To Unsubscribe or change delivery options go to:
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Re: [MBZ] OT - Replication errors

2007-05-24 Thread BillR
I am far from knowledgeable on this, but IIRC it is pretty normal for errors
to occur when a chromosome set replicates.  There is also a 'checking'
system that discards most of the errors.  Some get through and most don't
matter, but I suppose this accounts for much of the change we see in a
population over the years.
BillR  

-Original Message-
From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED]
On Behalf Of Redghost
Sent: Thursday, May 24, 2007 12:22 AM
To: Mercedes Discussion List
Subject: Re: [MBZ] OT - Replication errors

Hmmm.

So there are errors right off the bat?  That can not be good.  Well,  
I guess there are standard errors and deviations that do not really  
create damage in standard reproduction, so it should be fine for some  
errors in replication.

Maybe it was the point at which the deviations from a norm  
specification were induced that I was trying to see.  What would have  
the least probability of producing terminal errors and maintaining as  
close to original specifications?  Not that it matters if I am just  
going to be outsourced to a turkey baster anyway.

clay


On May 23, 2007, at 5:49 AM, Tony Wirtel wrote:


 Just screwing around with an old ipod trying to make sure it would
 work for my 6 year old to listen to.  Got one of those off the wall
 thoughts pop in to my empty head

 What would the replication errors be, or would there be, if a woman
 were to carry her own clone?  How many generations hence before
 errors would be induced if you used the original donor in succeeding
 generation vs. donation from prior generation to source the next?

 Off the wall, but I am sure there is enough brain power on the list
 to at least shine a very dim light on the topic

 --
 Clay
 Seattle Bioburner

 Clay:

 Not an expert, but there are ALWAYS replication errors; what changes
 are the quantity.  After that I believe its simply a matter of
 statistics of error probability taking over.  To VERY broadly
 generalize if you're error rate is 1%, over 10 generations the
 probability of success would be about 90%; if error rate is 99.9%,
 then over the same 10 generations you'd be at about 99%. This assumes
 much, perhaps the most important factor being that the error rate
 would not change.

 That said, with advances in science and medicine as well as cars that
 are more reliable while also increasingly DIY unfriendly men are
 pretty much SOL, anyway (grin).

 Tony Wirtel

 ___
 http://www.okiebenz.com
 For new parts see official list sponsor: http://www.buymbparts.com/
 For used parts email [EMAIL PROTECTED]

 To Unsubscribe or change delivery options go to:
 http://okiebenz.com/mailman/listinfo/mercedes_okiebenz.com


___
http://www.okiebenz.com
For new parts see official list sponsor: http://www.buymbparts.com/
For used parts email [EMAIL PROTECTED]

To Unsubscribe or change delivery options go to:
http://okiebenz.com/mailman/listinfo/mercedes_okiebenz.com





Re: [MBZ] OT - Replication errors

2007-05-24 Thread Rich Thomas
They were replicants whatever that meant.  There were a few that did 
not have time limits engineered in.  I recently heard that Harrison 
Ford's character (I forget his name in the flick) was one of these.  
H...


You might be thinking of the book, Do Androids Dream of Electric Sheep.

--R

Redghost wrote:

I think Blade Runner was dealing with androids not clones.
  





Re: [MBZ] OT - Replication errors

2007-05-24 Thread Donald Snook
Clay wrote: 

 

Um, babes ain't bananas, but I catch the drift. 

 

 

I have no idea what are you all are talking about.  But, I did catch
enough of the discussion that your line made me laugh! 

 

 

Donald H. Snook

1990 300SEL 137K (For Sale) 



Re: [MBZ] OT - Replication errors

2007-05-24 Thread Redghost
The movie was based on that Philip K. Dick book.  I did not know that  
he may have been a replicant.  I understood that Sean Young had been  
engineered without the limiter.  I guess with each iteration of the  
DVD release we will be getting more data to build on the story of  
just what may have transpired.


clay



On May 24, 2007, at 6:17 AM, Rich Thomas wrote:


They were replicants whatever that meant.  There were a few that did
not have time limits engineered in.  I recently heard that Harrison
Ford's character (I forget his name in the flick) was one of these.
H...

You might be thinking of the book, Do Androids Dream of Electric  
Sheep.


--R

Redghost wrote:

I think Blade Runner was dealing with androids not clones.




___
http://www.okiebenz.com
For new parts see official list sponsor: http://www.buymbparts.com/
For used parts email [EMAIL PROTECTED]

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[MBZ] OT - Replication errors

2007-05-23 Thread Redghost
Just screwing around with an old ipod trying to make sure it would  
work for my 6 year old to listen to.  Got one of those off the wall  
thoughts pop in to my empty head


What would the replication errors be, or would there be, if a woman  
were to carry her own clone?  How many generations hence before  
errors would be induced if you used the original donor in succeeding  
generation vs. donation from prior generation to source the next?


Off the wall, but I am sure there is enough brain power on the list  
to at least shine a very dim light on the topic





--
Clay
Seattle Bioburner

1972 220D - Gump
1995 E300D - Cleo
1987 300SDL - POS - DOA
The FSM would drive a Diesel Benz




Re: [MBZ] OT - Replication errors

2007-05-23 Thread Tom Hargrave
If a man is standing in the middle of the woods, 6 miles from any women  he
says something, is he still wrong?

Thanks,
Tom Hargrave
www.kegkits.com
256-656-1924
 

-Original Message-
From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED]
On Behalf Of Redghost
Sent: Tuesday, May 22, 2007 9:13 PM
To: Mercedes Discussion List
Subject: [MBZ] OT - Replication errors

Just screwing around with an old ipod trying to make sure it would  
work for my 6 year old to listen to.  Got one of those off the wall  
thoughts pop in to my empty head

What would the replication errors be, or would there be, if a woman  
were to carry her own clone?  How many generations hence before  
errors would be induced if you used the original donor in succeeding  
generation vs. donation from prior generation to source the next?

Off the wall, but I am sure there is enough brain power on the list  
to at least shine a very dim light on the topic




--
Clay
Seattle Bioburner

1972 220D - Gump
1995 E300D - Cleo
1987 300SDL - POS - DOA
The FSM would drive a Diesel Benz


___
http://www.okiebenz.com
For new parts see official list sponsor: http://www.buymbparts.com/
For used parts email [EMAIL PROTECTED]

To Unsubscribe or change delivery options go to:
http://okiebenz.com/mailman/listinfo/mercedes_okiebenz.com




[MBZ] OT - Replication errors

2007-05-23 Thread Tony Wirtel


Just screwing around with an old ipod trying to make sure it would
work for my 6 year old to listen to.  Got one of those off the wall
thoughts pop in to my empty head

What would the replication errors be, or would there be, if a woman
were to carry her own clone?  How many generations hence before
errors would be induced if you used the original donor in succeeding
generation vs. donation from prior generation to source the next?

Off the wall, but I am sure there is enough brain power on the list
to at least shine a very dim light on the topic

--
Clay
Seattle Bioburner


Clay:

Not an expert, but there are ALWAYS replication errors; what changes
are the quantity.  After that I believe its simply a matter of
statistics of error probability taking over.  To VERY broadly
generalize if you're error rate is 1%, over 10 generations the
probability of success would be about 90%; if error rate is 99.9%,
then over the same 10 generations you'd be at about 99%. This assumes
much, perhaps the most important factor being that the error rate
would not change.

That said, with advances in science and medicine as well as cars that
are more reliable while also increasingly DIY unfriendly men are
pretty much SOL, anyway (grin).

Tony Wirtel



Re: [MBZ] OT - Replication errors

2007-05-23 Thread Ed Booher

On 5/22/07, Redghost [EMAIL PROTECTED] wrote:

What would the replication errors be, or would there be, if a woman
were to carry her own clone?  How many generations hence before
errors would be induced if you used the original donor in succeeding
generation vs. donation from prior generation to source the next?

Off the wall, but I am sure there is enough brain power on the list
to at least shine a very dim light on the topic


Well, the largest problem you run into first is that the process of
cloning is not exact as of yet. Too many errors are still introduced
merely by man trying to meddle in a natural process. So at this time,
you'd have genetic errors in the first generation. Now, supposing that
man ever gets to a point where genetic clones of humans are a 100%
reliable possibility, then you get into an even different problem. The
clone being a duplicate representation of the mother carrying the
child, the mother's body would be unable to tell any difference
between the child and the mother. Meaning any disease, cancer, etc
that the mother may have/contract during the 9 month incubation would
have a far larger risk of being transferred to the clone child as the
genetics involved can not tell a difference and begin to rewrite the
clone DNA with the same RNA rewriting the mothers.

Further, look at the plight of the banana. Some 65 or so years ago
(roughly, going by memory instead of taking research time to pull
proper data) there was a banana that was known as the Big Mike. People
that still remember the Mike say that it was a firmer, sweeter banana
than we have today. Heck, some of the listers may remember the Big
Mike. Every banana that we eat today, that we think of as the
banana, the bright yellow color, the curvature, the God inspired
easy open handle is a clone. They are all genetically identical. So
was the Big Mike, it too was a genetic clone. Every Mike was the same
on the cellular level. Today, you will not find a Mike. Period. They
are extinct.

A disease ran rampant through the Mike. It spread, eventually, to
every banana field in the world that grew the Mike. Because they were
cloned, there was no genetic alterations, no differences, that allowed
any strain of MIke to become impervious to the disease, and as such,
every last one was wiped out. Today, the same has started occuring to
the Cavendish Banana (the bright yellow, etc) and there may be one day
soon that we have to start eating a completely different banana again.
As the last of the Cavendish becomes extinct.

A perfect human clone would face the same fate after 20 or so
generations. There wouldn't be enough genetic differences left in the
gene pool to combat all diseases and the race would slowly die out.
Probably.

--
Knowledge is power... Power Corrupts. Study hard... Be Evil.