Good thoughts, although there are always exceptions. For example, if a crystal
contact is mediated by an extended domain that is capable of adopting multiple
conformations (due to elbow motion, for example), then it may allow multiple
crystal forms. It happens a lot in RNA crystals, but can
Dear James,
I'll second Manferd's post.
We have a membrane protein that crystallizes with a continuum of cell
dimensions, so different that you can't merge the data to reach full
completeness, but you could manage to gain MR solutions for some
discrete states of the continuum and ending up in
Dear James,
let's spin the thought a bit further. What if there is a new program
(Phaser-II) some day,
for which the coordinates in your "new crystal form" are all of a sudden
within the
radius of convergence again? Does this bring your "new crystal form"
back to the old
crystal form again?
I'd
Hmmm…interesting James!. I don’t usually make a habit of trying to form a
class, or losing face because of a point, -or even making a group in space..
But..
Id say it is neither different form nor different habit. -since these are
centuries old terms -and still valuable, - from mineralogy
I have a semantics question, and I know how much this forum loves
discussing semantics.
We've all experienced non-isomorphism, where two crystals, perhaps even
grown from the same drop, yield different data. Different enough so that
merging them makes your overall data quality worse. I'd say
