Re: [Felvtalk] Bone Marrow Testing for FELV positive Cat?

[Wendy]

Thank you so much, again, Amani

On Sep 19, 2019, at 8:13 PM, Amani Oakley 
mailto:aoak...@oakleylegal.com>> wrote:

Wendy

I was going to comment on that issue earlier, but I thought you had already 
gone ahead with the bone marrow testing. I am not sure there is any other 
treatment, regardless of the outcome of the testing. I personally agree with 
you that I probably would choose not to put my cat through bone marrow testing, 
when it really can’t affect the outcome. I am glad to hear that he is feeling 
better after the two transfusions. Use the Doxy-Pred-Winstrol combination now, 
and hopefully, your kitten’s haematocrit doesn’t end up falling after the 
temporary boost from the blood transfusion. The life span of a red blood cell 
is 120 days (at least in humans), and the blood transfusions will have red 
cells at different stages of their life spans, so you probably already know 
that the effect of the transfusions will probably only last 3 months or so. 
Hopefully by then the Winstrol would have kicked in to assist the bone marrow 
in producing red cells.

Amani

From: Felvtalk 
mailto:felvtalk-boun...@felineleukemia.org>>
 On Behalf Of Wendy
Sent: September 19, 2019 10:41 PM
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat?

Hello, Thank you all for your replies earlier today.  Our cats’ red count is 
coming back after 2 blood transfusions, and we started doxy today.  He is 
eating, drinking, purring, has much better energy, is back to talking, etc.  We 
are awaiting results that we should have tomorrow morning on the test of his 
lymphocytes using blood that was drawn before the blood transfusions.  If the 
test comes back showing that the lymphocytes contain cancer cells, then we have 
our answer.  If the test comes back showing that the lymphocytes do not contain 
cancer cells, then it has been suggested that we do bone marrow testing asap 
tomorrow afternoon.  My understanding is that the bone marrow test would likely 
either show that he has myelodysplasia or cancer in his bone marrow.  My 
question is: Would the suggested treatment of Doxy + Pred + Winstrol change if 
we find out that our cat has myelodysplasia vs if he has cancer in his bone 
marrow?  If the treatment is the same, then I question putting our cat at the 
risk of anesthesia, lowering his red count, infection, etc.  The plan is to 
start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being 
told that if we want to test his bone marrow we need to do it tomorrow morning 
before we start giving him steroids.  In addition, his chest x-ray today was 
clean, and his abdominal ultrasound showed a slightly enlarge spleen and either 
a few slightly enlarged lymph nodes or possibly a few small satellite spleens, 
all of which seems can be expected with the anemia and / or infection, and 
therefore was not cause for concern.

Following are the background facts, which I also posted this morning:  Our FELV 
positive neutered male cat approximately 1 and ½ years old has gotten very sick 
suddenly. He is a house cat, and he was neutered in May of 2019.  A few days 
ago, he became lethargic and lost interest in eating.  We had his blood drawn 
yesterday and he had iv fluids yesterday, and today we were told he needed a 
blood transfusion (or two) and more iv fluids, and then a bone marrow test 
tomorrow.  We were told that the first blood transfusion today was not very 
effective because he got so many iv fluids at the same time, so now they are 
going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work:
Tests ResultsRef. Range
Total Protein  6.1  5.2- 8.8 g/dL
Albumin 3.5   2.5- 3.9 g/dl
Globulin 2.6   2.3- 5.3 g/dL
A/G Ratio  1.30.35- 1.5
AST (SGOT)  106 (HIGH)   10-100 IU/L
ALT (SGPT)   3910- 100  IU/L
Alk Phosphatase406- 102  IU/L
GGT  11- 10 IU/L
Total Bilirubin   0.1   0.1- 0.4 mg/dL
BUN

Re: [Felvtalk] Bone Marrow Testing for FELV positive Cat?

[Amani Oakley]

Wendy

I was going to comment on that issue earlier, but I thought you had already 
gone ahead with the bone marrow testing. I am not sure there is any other 
treatment, regardless of the outcome of the testing. I personally agree with 
you that I probably would choose not to put my cat through bone marrow testing, 
when it really can't affect the outcome. I am glad to hear that he is feeling 
better after the two transfusions. Use the Doxy-Pred-Winstrol combination now, 
and hopefully, your kitten's haematocrit doesn't end up falling after the 
temporary boost from the blood transfusion. The life span of a red blood cell 
is 120 days (at least in humans), and the blood transfusions will have red 
cells at different stages of their life spans, so you probably already know 
that the effect of the transfusions will probably only last 3 months or so. 
Hopefully by then the Winstrol would have kicked in to assist the bone marrow 
in producing red cells.

Amani

From: Felvtalk  On Behalf Of Wendy
Sent: September 19, 2019 10:41 PM
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat?

Hello, Thank you all for your replies earlier today.  Our cats' red count is 
coming back after 2 blood transfusions, and we started doxy today.  He is 
eating, drinking, purring, has much better energy, is back to talking, etc.  We 
are awaiting results that we should have tomorrow morning on the test of his 
lymphocytes using blood that was drawn before the blood transfusions.  If the 
test comes back showing that the lymphocytes contain cancer cells, then we have 
our answer.  If the test comes back showing that the lymphocytes do not contain 
cancer cells, then it has been suggested that we do bone marrow testing asap 
tomorrow afternoon.  My understanding is that the bone marrow test would likely 
either show that he has myelodysplasia or cancer in his bone marrow.  My 
question is: Would the suggested treatment of Doxy + Pred + Winstrol change if 
we find out that our cat has myelodysplasia vs if he has cancer in his bone 
marrow?  If the treatment is the same, then I question putting our cat at the 
risk of anesthesia, lowering his red count, infection, etc.  The plan is to 
start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being 
told that if we want to test his bone marrow we need to do it tomorrow morning 
before we start giving him steroids.  In addition, his chest x-ray today was 
clean, and his abdominal ultrasound showed a slightly enlarge spleen and either 
a few slightly enlarged lymph nodes or possibly a few small satellite spleens, 
all of which seems can be expected with the anemia and / or infection, and 
therefore was not cause for concern.

Following are the background facts, which I also posted this morning:  Our FELV 
positive neutered male cat approximately 1 and ½ years old has gotten very sick 
suddenly. He is a house cat, and he was neutered in May of 2019.  A few days 
ago, he became lethargic and lost interest in eating.  We had his blood drawn 
yesterday and he had iv fluids yesterday, and today we were told he needed a 
blood transfusion (or two) and more iv fluids, and then a bone marrow test 
tomorrow.  We were told that the first blood transfusion today was not very 
effective because he got so many iv fluids at the same time, so now they are 
going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work:
Tests ResultsRef. Range
Total Protein  6.1  5.2- 8.8 g/dL
Albumin 3.5   2.5- 3.9 g/dl
Globulin 2.6   2.3- 5.3 g/dL
A/G Ratio  1.30.35- 1.5
AST (SGOT)  106 (HIGH)   10-100 IU/L
ALT (SGPT)   3910- 100  IU/L
Alk Phosphatase406- 102  IU/L
GGT  11- 10 IU/L
Total Bilirubin   0.1   0.1- 0.4 mg/dL
BUN 1514- 36 mg/dl
Creatinine  0.9   0.6- 2.4 mg/dl
BUN/Creatinine Ratio   17 4-33

Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

[Wendy]

Hello Amani,  Thank you very much for your detailed response.  I apologize for 
my poor explanation regarding the blood transfusion not being effective. You 
are correct, that it was merely a dilution effect from the iv fluids.  All the 
best, Wendy

From: Amani Oakley 
Sent: Thursday, September 19, 2019 1:50 PM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

As others have mentioned in reply to your post, I have used a combination of 
Winstrol (Stanozolol), Doxycycline and Prednisone. The blood work seems to show 
that there is an affect on both the red cell lines and platelets. That suggests 
that this is a bone marrow depression, and in turn that suggests that this is 
likely the effect of FeLV. My experience has been that the Winstrol seems to 
turn back on or encourage the growth of new bone marrow cells, and is really 
great for increasing red cell indices (red cell counts, haematocrit, 
haemoglobin, reticulocyte count), and I saw it take effect pretty quickly. My 
cat's haematocrit was down to 10 after two separate rounds of blood transfusion.

By the way, I don't understand the explanation in your email, that you've been 
told that the blood transfusion wasn't effective because of too much IV fluids. 
That doesn't make a lot of sense. You are still infusing the same volume of red 
cells, whether that is diluted by the IV fluids or not. I agree that the lab 
results may show a dilution effect because of the IV fluids, but that just 
means that when the excess fluid is pee'd out, then the haematocrit result will 
go up. By the way, if there is truly a dilution effect, it will show on a 
number of lab results like sodium, potassium, urea and platelets.

What I had my cat on was:   Winstrol (stanozolol)  
1 mg, 2 times a day (though this can be dramatically increased if necessary)
 Doxycycline
  50 mg daily (can be given once, or split to 25 mg, 2 times a day)
 Prednisone/Prednisolone
  5 mg daily (can be given once, or split to 2.5 mg, 2 times a day)


Amani

From: Felvtalk 
mailto:felvtalk-boun...@felineleukemia.org>>
 On Behalf Of Wendy
Sent: September 19, 2019 1:26 AM
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT
Importance: High

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work that are not in normal range:
AST (SGOT) 106
Glucose 178
CPK 711
WBC 20.5
RBC 2.5
HGB 4.5
HCT 14
NRBC 9
Platelet Count 78
Neutrophils 1640
Lymphocytes 17630
Monocytes 1025
Basophils 205
Protein 2+
Reticulocyte 0.6 and 15000
Would you please let us know what we can do to help our cat?
Thank you, Wendy
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

[Felvtalk] Bone Marrow Testing for FELV positive Cat?

[Wendy]

Hello, Thank you all for your replies earlier today.  Our cats' red count is 
coming back after 2 blood transfusions, and we started doxy today.  He is 
eating, drinking, purring, has much better energy, is back to talking, etc.  We 
are awaiting results that we should have tomorrow morning on the test of his 
lymphocytes using blood that was drawn before the blood transfusions.  If the 
test comes back showing that the lymphocytes contain cancer cells, then we have 
our answer.  If the test comes back showing that the lymphocytes do not contain 
cancer cells, then it has been suggested that we do bone marrow testing asap 
tomorrow afternoon.  My understanding is that the bone marrow test would likely 
either show that he has myelodysplasia or cancer in his bone marrow.  My 
question is: Would the suggested treatment of Doxy + Pred + Winstrol change if 
we find out that our cat has myelodysplasia vs if he has cancer in his bone 
marrow?  If the treatment is the same, then I question putting our cat at the 
risk of anesthesia, lowering his red count, infection, etc.  The plan is to 
start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being 
told that if we want to test his bone marrow we need to do it tomorrow morning 
before we start giving him steroids.  In addition, his chest x-ray today was 
clean, and his abdominal ultrasound showed a slightly enlarge spleen and either 
a few slightly enlarged lymph nodes or possibly a few small satellite spleens, 
all of which seems can be expected with the anemia and / or infection, and 
therefore was not cause for concern.

Following are the background facts, which I also posted this morning:  Our FELV 
positive neutered male cat approximately 1 and ½ years old has gotten very sick 
suddenly. He is a house cat, and he was neutered in May of 2019.  A few days 
ago, he became lethargic and lost interest in eating.  We had his blood drawn 
yesterday and he had iv fluids yesterday, and today we were told he needed a 
blood transfusion (or two) and more iv fluids, and then a bone marrow test 
tomorrow.  We were told that the first blood transfusion today was not very 
effective because he got so many iv fluids at the same time, so now they are 
going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work:
Tests ResultsRef. Range
Total Protein  6.1  5.2- 8.8 g/dL
Albumin 3.5   2.5- 3.9 g/dl
Globulin 2.6   2.3- 5.3 g/dL
A/G Ratio  1.30.35- 1.5
AST (SGOT)  106 (HIGH)   10-100 IU/L
ALT (SGPT)   3910- 100  IU/L
Alk Phosphatase406- 102  IU/L
GGT  11- 10 IU/L
Total Bilirubin   0.1   0.1- 0.4 mg/dL
BUN 1514- 36 mg/dl
Creatinine  0.9   0.6- 2.4 mg/dl
BUN/Creatinine Ratio   17 4-33
Phosphorus4.4   2.4- 8.2 mg/dl
Glucose178 (HIGH) 64 - 170 mg/dL
Calcium 9.38.2- 10 .8  mg/dL
Magnesium2.0   1.5- 2.5 mEq/L
Sodium 153  145-158 mEq/L
Potassium  4.6   3.4- 5.6 mEq/L
NAIK Ratio 3332-41
Chloride121  104-128 mEq/L
Cholesterol9475- 220 mg/dl
Triglyceride108  25-160 mg/dl
Amylase   611  100-1200 IU/L
PrecisionPSL(tm)  10 8- 26 U/L Acute 
pancreatitis is unlikely. Chronic pancreatitis is not excluded.
CPK 711 (HIGH)  56-529 IU/L
WBC 20.5 (HIGH)3.5- 16.0 10'/µL
Corrected for NRBCs
ABC  2.5 (LOW)5.92-9.93 10°/µ L
HGB  

Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

[Amani Oakley]

As others have mentioned in reply to your post, I have used a combination of 
Winstrol (Stanozolol), Doxycycline and Prednisone. The blood work seems to show 
that there is an affect on both the red cell lines and platelets. That suggests 
that this is a bone marrow depression, and in turn that suggests that this is 
likely the effect of FeLV. My experience has been that the Winstrol seems to 
turn back on or encourage the growth of new bone marrow cells, and is really 
great for increasing red cell indices (red cell counts, haematocrit, 
haemoglobin, reticulocyte count), and I saw it take effect pretty quickly. My 
cat's haematocrit was down to 10 after two separate rounds of blood transfusion.

By the way, I don't understand the explanation in your email, that you've been 
told that the blood transfusion wasn't effective because of too much IV fluids. 
That doesn't make a lot of sense. You are still infusing the same volume of red 
cells, whether that is diluted by the IV fluids or not. I agree that the lab 
results may show a dilution effect because of the IV fluids, but that just 
means that when the excess fluid is pee'd out, then the haematocrit result will 
go up. By the way, if there is truly a dilution effect, it will show on a 
number of lab results like sodium, potassium, urea and platelets.

What I had my cat on was:   Winstrol (stanozolol)  
1 mg, 2 times a day (though this can be dramatically increased if necessary)
 Doxycycline
  50 mg daily (can be given once, or split to 25 mg, 2 times a day)
 Prednisone/Prednisolone
  5 mg daily (can be given once, or split to 2.5 mg, 2 times a day)


Amani

From: Felvtalk  On Behalf Of Wendy
Sent: September 19, 2019 1:26 AM
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT
Importance: High

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work that are not in normal range:
AST (SGOT) 106
Glucose 178
CPK 711
WBC 20.5
RBC 2.5
HGB 4.5
HCT 14
NRBC 9
Platelet Count 78
Neutrophils 1640
Lymphocytes 17630
Monocytes 1025
Basophils 205
Protein 2+
Reticulocyte 0.6 and 15000
Would you please let us know what we can do to help our cat?
Thank you, Wendy
___
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Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - reposting as other email too long

[gidget43]

I very seldom post here, but your baby is very anemic.  HCT 14% and if it 
continues to drop will need a transfusion.  Many here at one time suggested 
Winstrol for anemia.  
https://www.rxlist.com/winstrol-side-effects-drug-center.htm    I am sure 
others will chime in here, but this was said to work.  
https://gainsmadness.com/what-is-winstrol-cycle/



-Original Message-
From: Wendy 
To: felvtalk@felineleukemia.org 
Sent: Thu, Sep 19, 2019 10:08 am
Subject: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - reposting as other 
email too long

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div.yiv9841986119WordSection1 {} --Hello, Our FELV positive neutered male 
cat approximately 1 and ½ years old has gotten very sick suddenly.  He is a 
house cat, and he was neutered in May of 2019.  Would you please let us know 
what we can do to help our much-loved cat?  A few days ago, he became lethargic 
and lost interest in eating.  We had his blood drawn yesterday and he had iv 
fluids yesterday, and today we were told he needed a blood transfusion (or two) 
and more iv fluids, and then a bone marrow test tomorrow.  We were told that 
the first blood transfusion today was not very effective because he got so many 
iv fluids at the same time, so now they are going to give him another 
transfusion.  As background, we rescued him as a stray from Barbados in October 
2018 when he was about 6 months old, and he has been healthy, active, happy and 
gaining weight, despite being FELV positive.  Since October 2018, we cured him 
of giardia and bartonella henselae.  On 12/31/2018, he tested positive for the 
ELISA and IFA, although his blood work was in normal ranges at that time.  In 
03/2019, we started giving him 1 t-cyte shot once per month, and we started 
giving him 1ml of interferon per days for 7 days on and then 7 days off, 
repeated.  We have continued the interferon and t-cyte in this manner ever 
since 03/2019.  Just yesterday, here are the results of his blood work that are 
not in normal range: AST (SGOT) 106 Glucose 178 CPK 711 WBC 20.5 RBC 2.5 HGB 
4.5 HCT 14 NRBC 9 Platelet Count 78 Neutrophils 1640 Lymphocytes 17630 
Monocytes 1025 Basophils 205 Protein 2+ Reticulocyte 0.6 and 15000 Would you 
please let us know what we can do to help our cat? Thank you, Wendy 
___
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Felvtalk@felineleukemia.org
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___
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[Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - reposting as other email too long

[Wendy]

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work that are not in normal range:
AST (SGOT) 106
Glucose 178
CPK 711
WBC 20.5
RBC 2.5
HGB 4.5
HCT 14
NRBC 9
Platelet Count 78
Neutrophils 1640
Lymphocytes 17630
Monocytes 1025
Basophils 205
Protein 2+
Reticulocyte 0.6 and 15000
Would you please let us know what we can do to help our cat?
Thank you, Wendy
___
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Felvtalk@felineleukemia.org
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Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

[LORRAINE JOHNSTON]

Oral dosing is okay with human interferon Alfa 2b. You might want to try 
retromad1, imported from Malaysia. There is a man, John B., on the fivtherapy 
yahoogroup who has a colony of felv and fiv cats, and lots of good advice. You 
might want to join that group (felv is discussed there, even though the group 
name is fivtherapy). Also, I will get in touch with 

John via private email about your kitty. He is in South Africa, so if you’re in 
the US, there might be a time delay.


BTW, I don’t hear too many success stories about tcyte. Not that it causes 
harm, to my knowledge, just that it doesn't seem to help.


- Lorraine 

> On September 19, 2019 at 7:50 AM Wendy  wrote:
> 
>  
> Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered 
> for our cat from Road Runner Pharmacy.  It shows Cat on the label.  He takes 
> the interferon orally, and not by injection.  Sorry for all of the responses, 
> I’m trying to figure out this system and worried about our precious cat.  
> Does this help?  Thank you so much, Wendy
> 
> On Sep 18, 2019, at 10:26 PM, Wendy < we...@wendyfrank.net 
> mailto:we...@wendyfrank.net > wrote:
> 
> 
> > > 
> > Hello, Our FELV positive neutered male cat approximately 1 and ½ 
> > years old has gotten very sick suddenly.  He is a house cat, and he was 
> > neutered in May of 2019.  Would you please let us know what we can do to 
> > help our much-loved cat?  A few days ago, he became lethargic and lost 
> > interest in eating.  We had his blood drawn yesterday and he had iv fluids 
> > yesterday, and today we were told he needed a blood transfusion (or two) 
> > and more iv fluids, and then a bone marrow test tomorrow.  We were told 
> > that the first blood transfusion today was not very effective because he 
> > got so many iv fluids at the same time, so now they are going to give him 
> > another transfusion.  As background, we rescued him as a stray from 
> > Barbados in October 2018 when he was about 6 months old, and he has been 
> > healthy, active, happy and gaining weight, despite being FELV positive.  
> > Since October 2018, we cured him of giardia and bartonella henselae.  On 
> > 12/31/2018, he tested positive for the ELISA and IFA, although his blood 
> > work was in normal ranges at that time.  In 03/2019, we started giving him 
> > 1 t-cyte shot once per month, and we started giving him 1ml of interferon 
> > per days for 7 days on and then 7 days off, repeated.  We have continued 
> > the interferon and t-cyte in this manner ever since 03/2019.  Just 
> > yesterday, here are the results of his blood work that are not in normal 
> > range:
> > 
> > AST (SGOT) 106
> > 
> > Glucose 178
> > 
> > CPK 711
> > 
> > WBC 20.5
> > 
> > RBC 2.5
> > 
> > HGB 4.5
> > 
> > HCT 14
> > 
> > NRBC 9
> > 
> > Platelet Count 78
> > 
> > Neutrophils 1640
> > 
> > Lymphocytes 17630
> > 
> > Monocytes 1025
> > 
> > Basophils 205
> > 
> > Protein 2+
> > 
> > Reticulocyte 0.6 and 15000
> > 
> > Would you please let us know what we can do to help our cat?
> > 
> > Thank you, Wendy
> > 
> > > 


 

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Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

[Wendy]

He is getting the interferon orally and it is never being injected.

On Sep 18, 2019, at 10:26 PM, Wendy 
mailto:we...@wendyfrank.net>> wrote:

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work that are not in normal range:
AST (SGOT) 106
Glucose 178
CPK 711
WBC 20.5
RBC 2.5
HGB 4.5
HCT 14
NRBC 9
Platelet Count 78
Neutrophils 1640
Lymphocytes 17630
Monocytes 1025
Basophils 205
Protein 2+
Reticulocyte 0.6 and 15000
Would you please let us know what we can do to help our cat?
Thank you, Wendy
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Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

[Wendy]

Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for 
our cat from Road Runner Pharmacy.  It shows Cat on the label.  He takes the 
interferon orally, and not by injection.  Sorry for all of the responses, I’m 
trying to figure out this system and worried about our precious cat.  Does this 
help?  Thank you so much, Wendy

On Sep 18, 2019, at 10:26 PM, Wendy 
mailto:we...@wendyfrank.net>> wrote:

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work that are not in normal range:
AST (SGOT) 106
Glucose 178
CPK 711
WBC 20.5
RBC 2.5
HGB 4.5
HCT 14
NRBC 9
Platelet Count 78
Neutrophils 1640
Lymphocytes 17630
Monocytes 1025
Basophils 205
Protein 2+
Reticulocyte 0.6 and 15000
Would you please let us know what we can do to help our cat?
Thank you, Wendy
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Re: [Felvtalk] Felvtalk Digest, Vol 57, Issue 1

[Wendy]

Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for 
our cat from Road Runner Pharmacy.  It shows Cat on the label.  Does this help? 
 Thank you so much, Wendy

> On Sep 18, 2019, at 11:03 PM, "felvtalk-requ...@felineleukemia.org" 
>  wrote:
> 
> Send Felvtalk mailing list submissions to
>felvtalk@felineleukemia.org
> 
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> 
> or, via email, send a message with subject or body 'help' to
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> 
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> 
> When replying, please edit your Subject line so it is more specific
> than "Re: Contents of Felvtalk digest..."
> Today's Topics:
> 
>   1. PLEASE HELP ASAP - VERY SICK FELV CAT (Wendy)
>   2. PLEASE HELP ASAP - VERY SICK FELV CAT - REPOSTING WITH FULL
>  BLOOD WORK (Wendy)
> 
> 
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Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT

[Wendy]

Hello Lorraine, it is interferon alpha 2B compounded that my vet ordered for 
our cat from Road Runner Pharmacy.  It shows Cat on the label.  Does this help? 
 Thank you so much, Wendy

On Sep 18, 2019, at 10:26 PM, Wendy 
mailto:we...@wendyfrank.net>> wrote:

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work that are not in normal range:
AST (SGOT) 106
Glucose 178
CPK 711
WBC 20.5
RBC 2.5
HGB 4.5
HCT 14
NRBC 9
Platelet Count 78
Neutrophils 1640
Lymphocytes 17630
Monocytes 1025
Basophils 205
Protein 2+
Reticulocyte 0.6 and 15000
Would you please let us know what we can do to help our cat?
Thank you, Wendy
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Re: [Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - REPOSTING WITH FULL BLOOD WORK

[LORRAINE JOHNSTON]

You are using feline interferon omega, yes? Not human interferon? The human 
version can be given orally for stomatitis  but if injected it will eventually 
cause an allergic reaction.


- Lorraine

> On September 19, 2019 at 2:02 AM Wendy  wrote:
> 
> 
> Hello, Our FELV positive neutered male cat approximately 1 and ½ years 
> old has gotten very sick suddenly.  He is a house cat, and he was neutered in 
> May of 2019.  Would you please let us know what we can do to help our 
> much-loved cat?  A few days ago, he became lethargic and lost interest in 
> eating.  We had his blood drawn yesterday and he had iv fluids yesterday, and 
> today we were told he needed a blood transfusion (or two) and more iv fluids, 
> and then a bone marrow test tomorrow.  We were told that the first blood 
> transfusion today was not very effective because he got so many iv fluids at 
> the same time, so now they are going to give him another transfusion.  As 
> background, we rescued him as a stray from Barbados in October 2018 when he 
> was about 6 months old, and he has been healthy, active, happy and gaining 
> weight, despite being FELV positive.  Since October 2018, we cured him of 
> giardia and bartonella henselae.  On 12/31/2018, he tested positive for the 
> ELISA and IFA, although his blood work was in normal ranges at that time.  In 
> 03/2019, we started giving him 1 t-cyte shot once per month, and we started 
> giving him 1ml of interferon per days for 7 days on and then 7 days off, 
> repeated.  We have continued the interferon and t-cyte in this manner ever 
> since 03/2019.  Just yesterday, here are the results of his blood work:
> 
>  Tests ResultsRef. Range  
>  Units
> 
>  Total Protein  6.1   5.2- 8.8
>  g/dL
> 
>  Albumin 3.5   2.5- 3.9   
>   g/dl
> 
>  Globulin 2.6   2.3- 5.3  
>g/dL
> 
>  A/G Rat io  1.30.35- 1.5
> 
>  AST (SGOT)  106 (HIGH)   10-100  
>   IU/L
> 
>  ALT (SGPT)   3910- 100   
>  IU/L
> 
>  Alk Phosphatase406- 102  
>IU/L
> 
>  GGT  1  1- 10
>   IU/L
> 
>  Total Bilirubin0.1   0.1- 0.4
>  mg/dL
> 
>  BUN 1514- 36 
> mg/dl
> 
>  Creatinine  0.9   0.6- 2.4   
>   mg/dl
> 
>  BUN/Creatinine Ratio   17 4-33
> 
>  Phosphorus4.4   2.4- 8.2 
> mg/dl
> 
>  Glucose178 (HIGH)
>64 - 170mg/dL
>  
> 
>  Calcium 9.38.2- 10 .8
>m g/dL
> 
>  Magnesium2.0   1.5- 2.5  
>mEq/L
> 
>  Sodium 153  145-158  
>   mEq/L
> 
>  Potassium  4.6   3.4- 5.6
>  mEq/L
> 
>  NAIK Ratio 3332-41
> 
>  Chloride121  104-128 
>mEq/L
> 
>  Cholesterol9475- 220 
>mg/dl
> 
>  Triglyceride108  25-160  
>   mg/dl
> 
>  Amylase   611  100-1200  
> IU/L
> 
>  PrecisionPSL™  10 8- 26  
>  U/L Acute pancrea titis is unlikely. Chronic pancreatitis is 
> not excluded
> 
>  by a norm al PrecisionPSL™.
> 
>  
> 
> CPK711 (HIGH)  56-529 IU/L
> 
>  
> 
> WBC 20.5 (HIGH)3.5- 16.0  
> 10'/µL
> 
>  Corrected for NRBCs
>  
> 
> ABC  2.5 (LOW)5.92-9.93   
> 10°/µ L
> 
> HGB   4.5 (LOW)9.3- 15 .9 
>  

[Felvtalk] PLEASE HELP ASAP - VERY SICK FELV CAT - REPOSTING WITH FULL BLOOD WORK

[Wendy]

Hello, Our FELV positive neutered male cat approximately 1 and ½ years old has 
gotten very sick suddenly.  He is a house cat, and he was neutered in May of 
2019.  Would you please let us know what we can do to help our much-loved cat?  
A few days ago, he became lethargic and lost interest in eating.  We had his 
blood drawn yesterday and he had iv fluids yesterday, and today we were told he 
needed a blood transfusion (or two) and more iv fluids, and then a bone marrow 
test tomorrow.  We were told that the first blood transfusion today was not 
very effective because he got so many iv fluids at the same time, so now they 
are going to give him another transfusion.  As background, we rescued him as a 
stray from Barbados in October 2018 when he was about 6 months old, and he has 
been healthy, active, happy and gaining weight, despite being FELV positive.  
Since October 2018, we cured him of giardia and bartonella henselae.  On 
12/31/2018, he tested positive for the ELISA and IFA, although his blood work 
was in normal ranges at that time.  In 03/2019, we started giving him 1 t-cyte 
shot once per month, and we started giving him 1ml of interferon per days for 7 
days on and then 7 days off, repeated.  We have continued the interferon and 
t-cyte in this manner ever since 03/2019.  Just yesterday, here are the results 
of his blood work:

Tests ResultsRef. Range 
  Units

Total Protein  6.1   5.2- 8.8   
  g/dL

Albumin 3.5   2.5- 3.9  
   g/dl

Globulin 2.6   2.3- 5.3 
g/dL

A/G Rat io  1.30.35- 1.5

AST (SGOT)  106 (HIGH)   10-100 
   IU/L

ALT (SGPT)   3910- 100  
  IU/L

Alk Phosphatase406- 102 
IU/L

GGT  1  1- 10   
   IU/L

Total Bilirubin0.1   0.1- 0.4   
  mg/dL

BUN 1514- 36
 mg/dl

Creatinine  0.9   0.6- 2.4  
   mg/dl

BUN/Creatinine Ratio   17 4-33

Phosphorus4.4   2.4- 8.2
 mg/dl

Glucose178 (HIGH)   64 
- 170mg/dL



Calcium 9.38.2- 10 .8   
m g/dL

Magnesium2.0   1.5- 2.5 
mEq/L

Sodium 153  145-158 
   mEq/L

Potassium  4.6   3.4- 5.6   
  mEq/L

NAIK Ratio 3332-41

Chloride121  104-128
mEq/L

Cholesterol9475- 220
mg/dl

Triglyceride108  25-160 
   mg/dl

Amylase   611  100-1200 
 IU/L

PrecisionPSL(tm)  10 8- 26  
 U/L Acute pancrea titis is unlikely. Chronic pancreatitis is not 
excluded

by a norm al PrecisionPSL(tm).

CPK711 (HIGH)  56-529 IU/L


WBC 20.5 (HIGH)3.5- 16.0
  10'/µL

Corrected for NRBCs



ABC  2.5 (LOW)5.92-9.93 
  10°/µ L

HGB   4.5 (LOW)9.3- 15 .9   
g/dL

HCT   29-48 
  % '

The hematocrit in th 27. (Normal range 29-48). A recent study has indicated 
that >23% of anemic cats are infected with one or more species of hemoplasma 
and several studies confirm that PCR is significantly more sensitive in 
detecting hemoplasma.



MCV  5737-61
  fl

MCH 18.2 11-21  
pg

MCHC  3230-38