From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com]
On Behalf Of Sebastian Ueckert
Sent: 06 February 2009 09:51
To: Ethan Wu
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] simulation question
Dear Ethan,
the simplest solution to solve your problem would be to use
: Friday, February 6, 2009 5:54:33 AM
Subject: Betr.: Re: [NMusers] simulation question
Dear Ethan,
Have you tried removing the $ESTIMATION step and replace all values with your
final estimations? What does your result file say after termination?
Sincerely
Rob
Sebastian Ueckert sebastian.ueck
]
On Behalf Of Nick Holford
Sent: Friday, February 06, 2009 6:39 AM
To: nmusers@globomaxnm.com
Subject: Re: [NMusers] simulation question
Hi,
I dont understand why this wasn't fixed in NONMEM VI. It was a well
known bug in NONMEM V and has caused lots of grief for users.
I hope the NONMEM VII
Dear Ethan,
Have you tried removing the $ESTIMATION step and replace all values with your
final estimations? What does your result file say after termination?
Sincerely
Rob
Sebastian Ueckert sebastian.ueck...@googlemail.com 02/06/09 10:51
On Thu, Feb 5, 2009 at 11:18 PM, Ethan Wu
Dear Ethan,
the simplest solution to solve your problem would be to use the bootstrap
command of PSN (http://psn.sourceforge.net/). With PSN installed you would
simply do:
bootstrap final_model.mod -samples=200
PSN would take care of unsuccessful runs and provide a nice summary of the
individual
-nmus...@globomaxnm.com] On
Behalf Of Sebastian Ueckert
Sent: Friday, February 06, 2009 10:51
To: Ethan Wu
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] simulation question
Dear Ethan,
the simplest solution to solve your problem would be to use the bootstrap
command of PSN (http
Hi,
I dont understand why this wasn't fixed in NONMEM VI. It was a well
known bug in NONMEM V and has caused lots of grief for users.
I hope the NONMEM VII developers have got this high on their list of
NONMEM bugs that need to be fixed.
Nick
Dear users,
I am trying to compare several
SUBSTANTIALLY INCREASING INITIAL ESTIMATE OF SIGMA
OR DECREASING INITIAL ESTIMATE OF OMEGA
From: Rob ter Heine rob.terhe...@slz.nl
To: nmusers@globomaxnm.com; ethan.w...@yahoo.com
Sent: Friday, February 6, 2009 5:54:33 AM
Subject: Betr.: Re: [NMusers] simulation
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com]
On Behalf Of Sebastian Ueckert
Sent: Friday, February 06, 2009 1:51 AM
To: Ethan Wu
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] simulation question
Dear Ethan,
the simplest solution
: Thursday, February 05, 2009 7:33 PM
To: Ethan Wu
Cc: nmusers@globomaxnm.com
Subject: Re: [NMusers] simulation question
You can use S+ (or R that has an advantage of being free) to control
nonmem, but you may need a bit of programming. One possible scheme is to
prepare template control stream
Dear users,
I am trying to compare several specific PK/PD study designs by:
-- run 200 simulations with the final model (develope from original dataset)
-- fit the final model to the 200 simulated dataset
To achieve above, I used $SIM SUBPROB=200 option
however, nonmem would completely
You can use S+ (or R that has an advantage of being free) to control
nonmem, but you may need a bit of programming. One possible scheme is to
prepare template control stream (with $SIM SUBPROB=1 option) and then
run the loop
for(i in 1:NumerOfIterations) {
# prepare control file from a
12 matches
Mail list logo
