I think this excerpt from 
http://www.fpl.fs.fed.us/documnts/pdf2004/fpl_2004_dorau001.pdf
pretty much answers the question of ionic silver vs silver particles:

"The mechanisms of the antimicrobial action of silver can be described as 
follows (17):

1. Silver ions form insoluble compounds in the cell wall with (and thereby 
inactivate) sulfhydryl groups, which are essential components of enzymes 
responsible for transmembranous energy metabolism and electrolyte transport. 
The result is a loss of fluids and electrolytes from the organisms, which dry 
out and die.

2. Silver ions block the respiratory chain of bacteria in the cytochrome 
oxidase and NADH-succinate- dehydroginase region.

3. Silver ions enter the cell and bind to bacterial DNA and bacterial spores. 
Silver can complex with electron donor groups that contain oxygen or nitrogen. 
Reversible binding of bases occurs without aggregation or disruption of the 
double helix structure of the cell nucleus. Intercalation of silver can lead to 
increased stability of the double helix.

4. Silver ions in low concentrations may penetrate a bacterial cell and cause 
structural damage to the cell envelope. Upon entering the cell, the molecule 
may dissociate, after which the silver binds to the DNA.

5. Metal ions, particularly silver, can also bond to phosphate groups, forming 
a positive dipole on the phosphate, followed by formation of a cyclic phosphate 
and cleavage of these molecules at the phosphodiester bond.

6. Silver DNA complexes occur at bases, which cause denaturation by displacing 
hydrogen bonds between adjacent nitrogens of purines and pyrimidines, thereby 
preventing replication.

Note that all these mechanisms relate to solvated silver ions, Ag+. The 
antibacterial properties of any metal come from its ions, which are generated 
from the neutral metal (1 5). In the presence of oxygen, metallic silver can be 
bactericidal because silver (I) oxide is soluble enough to release free silver 
ions (18). When dealing with metallic silver, though, it is important to note 
that antimicrobial activity depends on the extent of the active silver surface."



The exception may be that silver particles less than 10nm in size may 
inactivate some viruses by attaching directly to the viruses glycoprotein 
knobs. The occupation of the  glycoprotein knobs by silver particles prevents 
the virus from being able to attach itself to a host cell and renders it 
harmless. See:
http://www.jnanobiotechnology.com/content/3/1/6

It should be noted that ionic silver solutions also contain silver particles 
and therefore are effective against viruses as well bacteria and fungus. 

 - Steve N



From: Kathy [mailto:[email protected]] 
Sent: Friday, March 26, 2010 9:03 AM
To: [email protected]
Subject: CS>Can someone answer this question?

 
http://www.thetreeofliberty.com/vb/showthread.php?t=97212
 
 
 
 


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