Summer: I personally believe that there is a difference in the way the body handles the different forms of silver. When the body consumes a SALT, the metabolic response is different than when the body adsorbs a PROTEIN, or when the body adsorbs WATER. To restate, I believe the body reacts differently when introduced to an ELECTROLYTE, to FOOD, or to HYDRATION.
Silver Salts are ionic, and usually come in high PPM concentrations... Silver Iodide, Silver Bromide, Silver Nitrate, Silver Chloride, Silver Sulfate... It is very hard to ( if not impossible ) to create a quality ionic silver that has a high PPM without stabilizing it in some manner. Companies that sell these silver salts often refuse to tell you what form of silver they are selling, and go on and on about how small the "particles" are. Mild Silver Protein is typically about 19 - 25 % silver by content ( the remainer being protein ). Silver Protein is not ionic, but in the body, it releases silver ions. It is often sold in high concentrations as well. A good chemistry arguement can be made that they only difference between different silver products -- insofar as the direct effect of the silver being toxic -- is the actual concentration of silver, and the size of end particles. I'm just not completely convinced this is the case, although I have no evidence to offer. "Isolated" ionic and particulate silver, in my book, are superior products. You have silver and you have water. Ag-, Ag+, O, H, and some carbon thrown in as a possible anion. "Alot" of ionic silver is converted to silver chloride upon reaching the stomach and blood stream, but this does not seem to alter the effectiveness. Proponents of minute silver particles might tell you that ionic silver works because there is often 5-15% particulate content. Proponents of ionic silver might tell you that particulate silver works because there is 5-15% ionic content. Nobody has produced any in-body evidence to suggest that particulate silver or ionic silver is more or less effective... Although I have seen evidence of the effectiveness of highly ionic "isolated" colloidal silver as being very effective in the body. I've seen comparisons, on more than one occasion, that show quality "isolated" silver as more effective than MSP; in-vitro. I've seen a comparison that shows that a quality isolated "ionic" silver as more effective than a particulate colloidal silver... in-vitro... but this comparison cannot be viewed as accurate in comparison to in-body effectiveness, it only serves to prove that quality ionic silver is more effective if the ions reach the pathogen.... this 'if' is the whole reason the particulate silver was developed to begin with. Myself? I've been very pleased with results obtained from CS that is between 85% - 100% ionic ( depending on use ). For my answer to the herxheimer question: http://www.silvermedicine.org/colloidalsilverandbentonite.html about half way down this page is a commentary on the herxheimer reaction. To summarize, what "we" now refer to the herxheimer reaction is actually the general description of any number of symptoms caused by a change in the biological terrain of the body that directly effects the immune system response and bacterial load/balance of the body, and occurs as a direct result of the use of one particular substance, whereby this EFFECT is an enduced change necessary to restore optimal health. This can be caused by endotoxin as the result of bacterial die off. It can be a strong response to a pre-existing infection, that, due to the elimination of a competing infection, momentarily has a population explosion due to the changes in the biological terrain. It can be both, as well as flu-like symptoms that result from the immune system having to respond in like. Mesosilver is an "isolated" silver product ( as far as I know, at any rate ). Jason

