Dear Jonathan,
You said:
<<Beta 1,3 Glucans have been documented to reduce fatalities in rats
exposed to anthrax. See Proceedings BTR 2002. Also check the
prospectus for BTR 2003. NB the effect is useful both as prophylaxis
AND as treatment after infection. >>
**Dr. Gary Ostroff of Biopolymer Engineering, Inc. did a 30 minute
presentation at the BTR 2002.
Here is what Biopolymer Engineering, Inc. has to say about Beta 1,3
Glucans
and anthrax:
Anthrax
Surviving exposure to anthrax is a race against time. Anthrax spores are
dormant when they enter the body through inhalation or the skin. Once
macrophages engulf and attempt to destroy the anthrax, the spores germinate
and release toxins that kill the macrophages, eventually bursting the cells
and spewing forth anthrax bacteria that then infect other parts of the body.
The key to survival is whether the macrophage can kill the anthrax spore
before it germinates, produces the toxins, kills the macrophage and causes
anthrax disease.
Preclinical studies show that both PGG Beta Glucan and WGP Beta Glucan can
produce a heightened state of microbial killing capability in the
macrophages. This stimulation provides macrophages an advantage in their
fight against anthrax.
A series of mouse studies commissioned by the Defence R&D Canada --Suffield,
whose goal is to protect Canadian military forces against chemical and
biological warfare, recorded survival rates from lethal exposure to anthrax
in excess of 80% using systemic (injected) beta glucan, compared with
survival rates of only 20-50% in untreated animals. In addition, analysis of
the anthrax remaining in the lungs of the survival animals showed that more
than 90% of the beta glucan-treated animals were bacteria-free, meaning the
animals were cured 11 days after infection.
Subsequent mouse-anthrax research demonstrated that both prophylactic and
therapeutic oral administration of the immunomodulator WGP Beta Glucan
significantly increased the survival rate of infected mice. In animals,
prophylactically administered oral WGP Beta Glucan increased survival from
50% in control animals to 100% in treated animals (Figure 1). In animals,
therapeutically administered oral WGP Beta Glucan increased survival from
30% in control-infected animals up to 90% in immunomodulator treated animals
(Figure 2).
Graphics available here:
http://www.biopolymer.com/anthrax.htm
** Biopolymer Engineering, Inc. is not an independent lab. They sell
WGP Beta Glucan.
Someone help me out here. How is it that a CS producer cannot get the
government to loosen up and provide B. anthracis for the purpose of
experiementing, but from all appearances, Biopolymer Engineering, Inc. can?
According to Biopolymer Engineering, Inc. their scientific collaborators
include:
US Armed Forces Radiobiology Research Institute, and Defence R&D Canada --
Suffield
This makes no sense to me.
Regards,
Catherine
Regards,
Catherine
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