Although this is correct, I feel it is irrelevant. Silver chloride will not remain silver chloride in the blood stream. Trace amounts of ammonia which are present in the blood should quickly combine with silver ions of the silver nitrate to produce a complex ion called the diamminesilver(I) ion, [Ag(NH3)2]+. I would expect this to end up being diamminesilver chloride.
The diamminesilver ion is relatively soluble, and any silver chloride that did precipitate should quickly react with trace amounts of ammonia producing a solution in the blood of diamminesilver chloride. Then, in conjunction with other compounds in the blood, the slightly basic pH of blood, and silver particles, the diamminesilver should quickly reduce to silver atoms onto the silver particles causing them to grow slightly. Without the silver particles to plate out on, then they would instead reduce in areas exposed to light, and then the remaining ions reduce on those particles, resulting in a rapid increase in size, and possibly producing argyria. The result is that no silver ions would be measurable in the blood shortly after the enter the blood stream. Do you know if the ISE will record diamminesilver ions as silver ions or not? If not, then they would not be measurable even if they did not reduce to metallic silver. Marshall Frank Key wrote: > Regarding silver chloride solubility: > > I asked Dr. Maass to make a calculation based on the solubility product of > silver chloride in blood serum whose typical chloride content is 3500 ppm > (3300 - 3900 ppm per Merck Manual). Silver ions can exist at a concentration > of 1.94 x10-4 ppm which is 0.000194 ppm. This is the maximum concentration > of ionic silver that can exist in blood serum containing 3500 ppm of > chloride. > > That explains why an ISE cannot detect silver, the value is below the > detection limit of an ISE. > > Also see the solubility rules table see: > http://www.silver-colloids.com/Tutorials/Solubility_Rules.htm > > frank key > > -- > The Silver List is a moderated forum for discussing Colloidal Silver. > > Instructions for unsubscribing are posted at: http://silverlist.org > > To post, address your message to: [email protected] > Silver List archive: http://escribe.com/health/thesilverlist/index.html > > Address Off-Topic messages to: [email protected] > OT Archive: http://escribe.com/health/silverofftopiclist/index.html > > List maintainer: Mike Devour <[email protected]> -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: [email protected] Silver List archive: http://escribe.com/health/thesilverlist/index.html Address Off-Topic messages to: [email protected] OT Archive: http://escribe.com/health/silverofftopiclist/index.html List maintainer: Mike Devour <[email protected]>
