I think I may have finally figured out how one can get argyria when breathing in silver dust, and how silver dust ends up being eliminated by the body via the kidneys despite the large particle size.
I have puzzled how silver particles, too large to be absorbed, end up causing argyria or being eliminated by the kidneys. for people like silver mine workers. There are two possibilities: 1. If the cells of the lungs are deprived of oxygen causing hypoxia (Hypoxia mean low in oxygen), then the Mitochondrial release of H2O2 is extracellular. See http://www3.interscience.wiley.com/cgi-bin/abstract/109905841/ABSTRACT 2. The silver acts as an oxidizing catalyst causing hyperoxia of the cells (hyperoxia means too much oxygen), which interestingly enough also causes cells to produce H2O2. http://www.clinicalobgyn.com/pt/re/clnobgyn/abstract.00003081-200309000-00017.htm;jsessionid=CxnsZEjxsFPeZcdMg2S2T1QlRcqHtJp11yVi25MHcYrMRxHePXHQ!2112422791!-949856031!9001!-1 Hyperoxia increases H2O2 release by lung mitochondria and microsomes My hypothesis is that a silver particle covers one or more cells. These cells are cut off from oxygen (or over oxygenated) and begin expelling H2O2. The hydrogen peroxide then reacts with the silver producing silver oxide which is immediately absorbed into the blood and becomes silver chloride. Since the particles of silver breathed in are too large to get into the blood stream directly, there is nothing for the silver chloride to plate out on, until it is either expelled by the kidneys, or exposed to light in the skin and photoreduced. Once that happens more can plate out on those particles causing argyria. Marshall -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: [email protected] Silver List archive: http://escribe.com/health/thesilverlist/index.html Address Off-Topic messages to: [email protected] OT Archive: http://escribe.com/health/silverofftopiclist/index.html List maintainer: Mike Devour <[email protected]>
