Hi all,
Thanks a lot for you advices.

Here I post the output for running the peptideProphet at the command
line:


C:\Inetpub\wwwroot\ISB\data\probidoutput\ipimouse>xinteract  -
Ninteract.pep.xml
-p0.05 -l7 -OAFm  -I2 -I3 -I4 -I5 -I6 -I7 analysis100.xml
analysis125.xml analy
sis150.xml analysis200.xml analysis25.xml analysis460.xml
analysis50.xml analysi
s500.xml analysis75.xml analysisunbind.xml

xinteract (TPP v4.3 JETSTREAM rev 0, Build 200908071234 (MinGW))

running: "C:/Inetpub/tpp-bin/InteractParser "C:/Inetpub/wwwroot/tmp/
a01564/ISB/d
ata/probidoutput/ipimouse/interact.pep.xml" "analysis100.xml"
"analysis125.xml"
"analysis150.xml" "analysis200.xml" "analysis25.xml" "analysis460.xml"
"analysis
50.xml" "analysis500.xml" "analysis75.xml" "analysisunbind.xml" -L"7""
 file 1: analysis100.xml
 file 2: analysis125.xml
 file 3: analysis150.xml
 file 4: analysis200.xml
 file 5: analysis25.xml
 file 6: analysis460.xml
 file 7: analysis50.xml
 file 8: analysis500.xml
 file 9: analysis75.xml
 file 10: analysisunbind.xml
 processed altogether 9099 results


 results written to file c:/Inetpub/wwwroot/tmp/a01564/ISB/data/
probidoutput/ipi
mouse/interact.pep.xml

 direct your browser to http://localhost/interact.pep.shtml



command completed in 8 sec

running: "C:/Inetpub/tpp-bin/PeptideProphetParser "C:/Inetpub/wwwroot/
tmp/a01564
/ISB/data/probidoutput/ipimouse/interact.pep.xml" MINPROB=0.05 ACCMASS
FORCEDIST
R MALDI IGNORECHG=2 IGNORECHG=3 IGNORECHG=4 IGNORECHG=5 IGNORECHG=6
IGNORECHG=7"

using Accurate Mass Bins
maldi mode
Ignoring charge 2+ spectra.
Ignoring charge 3+ spectra.
Ignoring charge 4+ spectra.
Ignoring charge 5+ spectra.
Ignoring charge 6+ spectra.
Ignoring charge 7+ spectra.
Forcing output of mixture model
 (PROBID)
adding Accurate Mass mixture distr
init with PROBID Trypsin
MS Instrument info: Manufacturer: UNKNOWN, Model: UNKNOWN, Ionization:
UNKNOWN,
Analyzer: UNKNOWN, Detector: UNKNOWN

 PeptideProphet  (TPP v4.3 JETSTREAM rev 0, Build 200908071234
(MinGW)) AKeller@
ISB
 read in 8815 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, and 0 7+ spectra.
Initialising statistical models ...
Iterations:

>>>{{{{ At this point the debug popup box appear}}}}}

command "C:/Inetpub/tpp-bin/PeptideProphetParser "C:/Inetpub/wwwroot/
tmp/a01564/
ISB/data/probidoutput/ipimouse/interact.pep.xml" MINPROB=0.05 ACCMASS
FORCEDISTR
 MALDI IGNORECHG=2 IGNORECHG=3 IGNORECHG=4 IGNORECHG=5 IGNORECHG=6
IGNORECHG=7"
failed: Unknown error

command "C:/Inetpub/tpp-bin/PeptideProphetParser "C:/Inetpub/wwwroot/
tmp/a01564/
ISB/data/probidoutput/ipimouse/interact.pep.xml" MINPROB=0.05 ACCMASS
FORCEDISTR
 MALDI IGNORECHG=2 IGNORECHG=3 IGNORECHG=4 IGNORECHG=5 IGNORECHG=6
IGNORECHG=7"
exited with non-zero exit code: -1073741819
QUIT - the job is incomplete


To Natalie,
At v4.3.0, peptideProphet runs smoothly when NOT using the maldi mode.
I have tried to install TPP v4.3.1, but using the latest version I
can't run peptideProphet at all, even just using
xinteract  -Ninteract.pep.xml -p0.05 -l7 -O <list iof xml files>
Therefore I change back to 4.3.0

Thanks again~

Regards,
Melody


On Sep 23, 3:56 am, Natalie Tasman <[email protected]>
wrote:
> Also, consider upgrading to TPP 4.3.1, which contains several bug fixes.
>
> -Natalie
>
> On Sep 22, 2009, at 8:32 AM, Brian Pratt wrote:
>
> > If it's really the same problem, then it's not a surprise that those
> > files don't exist, since the protXML file didn't get created,
> > because the pepXML file never went through peptideProphet.  But that
> > doesn't quite sound like what you're describing - check the log to
> > make sure of what's really going on.
>
> > Brian
>
> > On Tue, Sep 22, 2009 at 1:02 AM, Melody Lam <[email protected]>
> > wrote:
>
> > Hi all!
>
> > I have encountered the same problem. I am also using TPP v4.3.0 on
> > Windows XP.
>
> > The output file "interact.prot.shtml" and the stylesheet
> > "interact.prot.xsl" files are not found in the directory of the input
> > file "interact.pep.xml".
> > However, by manually running the following line in the command prompt:
> > c:\Inetpub\tpp-bin\protxml2html.pl -file directory/interact.prot.xml
> > The output file interact.prot.shtml works as expected.
>
> > I just wonder why throught the GUI the above command is not executed.
>
> > Regards,
> > Melody
>
> > On Sep 18, 2:22 am, Brian Pratt <[email protected]> wrote:
> > > It appears to have never been run though peptideProphet.
>
> > > I should add a bit of logic to proteinProphet to catch that and
> > issue a more
> > > useful error message.
>
> > > On Thu, Sep 17, 2009 at 10:52 AM, Brian Pratt
> > <[email protected]>wrote:
>
> > > > I'll have a quick look at this.
>
> > > > Brian
>
> > > >   On Thu, Sep 17, 2009 at 12:13 AM, YAN <[email protected]>
> > wrote:
>
> > > >> Hi everyone!
> > > >> Here are some more supplementary information from the output
> > screen of
> > > >> TPP:
>
> > > >>  Command 1
>
> > > >>  c:\Inetpub\tpp-bin\ProteinProphet c:/Inetpub/wwwroot/ISB/data/
> > > >> probidoutput/ipimouse/interact.pep.xml c:/Inetpub/wwwroot/ISB/
> > data/
> > > >> probidoutput/ipimouse/interact.prot.xml
>
> > --------------------------------------------------------------------------------
>
> > > >> Command FAILED
>
> > > >>  Command 2 [Thu Sep 17 14:33:13 2009]        [ Show / Hide ]
>
> > > >>  c:\Inetpub\tpp-bin\protxml2html.pl -file c:/Inetpub/wwwroot/
> > ISB/data/
> > > >> probidoutput/ipimouse/interact.prot.xml HTML
>
> > --------------------------------------------------------------------------------
>
> > > >> ProteinProphet (C++) by Insilicos LLC and LabKey Software,
> > after the
> > > >> original Perl by A. Keller (TPP v4.3 JETSTREAM rev 0, Build
> > > >> 200908071234 (MinGW))
> > > >>  (xml input) (report Protein Length) (using degen pep info)
> > > >> . . . reading in c:/Inetpub/wwwroot/ISB/data/probidoutput/
> > ipimouse/
> > > >> interact.pep.xml. . .
> > > >> . . . read in 0 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, 0 7+ spectra
> > with
> > > >> min prob 0.05
> > > >> no data - quittingEND OUTPUT
> > > >> Writing results to html file: c:/Inetpub/wwwroot/ISB/data/
> > probidoutput/
> > > >> ipimouse/interact.prot.html
> > > >> Command FAILED
> > > >> ................................................
>
> > > >> I am running TPP on Windows XP and I just wonder why the
> > program can't
> > > >> read the data from the pepxml file.
> > > >> I have also uploaded the pepXML file to this group at
> > > >>http://groups.google.com/group/spctools-discuss/web/yan.zip
>
> > > >> Thanks a lot!
> > > >>  Yan

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