Brian,

I run xinteract on Release and developement versions of the TPP with debug
option -t! and -t# respectively.
====================================================================================================
With Release version of the TPP tools ....

/home/APCF/tpp/bin/xinteract -t! -Njagan-J78.pepprophet.xml -p0.05 -l7 -x20
-O jagan-J78.pep.xml
All the results files including logs are kept on wiki page which can be
downloaded using the following link ...

https://search.apcf.edu.au/wiki/index.php/Apcfwiki:Community_Portal#APCF_Downloads
cliking on "DevelopmentRun.zip(xinteract run with release version and option
"-t!") <https://search.apcf.edu.au/dbdownloads/DevelopmentRun.zip>
------------------------------------------------------------------------------------------------------------------------------------------------------------------
With developmental version of the TPP ....

/home/APCF/tpp/bin/xinteract -t# -Njagan-J78.pepprophet.xml -p0.05 -l7 -x20
-O jagan-J78.pep.xml
All the results files including logs are kept on wiki page which can be
downloaded using the following link ...

https://search.apcf.edu.au/wiki/index.php/Apcfwiki:Community_Portal#APCF_Downloads
cliking on "ReleaseDevelopmentRun.zip(xinteract run with development version
and option "-t#" after release version run with an option
"-t!")<https://search.apcf.edu.au/dbdownloads/ReleaseDevelopmentRun.zip>

===================================================================================================
 The STDOUT of the latter run is as follows ...

It looks like there are erros, the regression tests were FAILURED in
PeptideProphet run and the PeptideProphet.bad.tagList etc also included in
the zipped files.

I wonder whether anyone has any idea about this problem.

------------------------------------------------------------------------------------------------------------------------------------------------------------------

[r...@apcf-hn3 2010-06-23]# /home/APCF/tpp/bin/xinteract -t#
-Njagan-J78.pepprophet.xml -p0.05 -l7 -x20 -O jagan-J78.pep.xml

/home/APCF/tpp/bin/xinteract (TPP v4.4 JETSTREAM (unstable development
prerelease) rev 0, Build 201006041141 (linux))
 performing regression test (# option in use, will continue in case of
error)...

running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/InteractParser
-t#-Njagan-J78.pepprophet.xml_-p0.05_-l7_-x20_-O_jagan-J78.pep.xml
'jagan-J78.pepprophet.xml' 'jagan-J78.pep.xml' -L'7'"
running regression test on basis file
jagan-J78.pepprophet.xml.interactParser.-Njagan-J78.pepprophet.xml_-p0.05_-l7_-x20_-O_jagan-J78.pep.xml.tagList
 file 1: jagan-J78.pep.xml
 processed altogether 3429 results


 results written to file
/mnt/sanfs/APCF/results/tpp/2010-06-23/jagan-J78.pepprophet.shtml



        interactParser regression test success
command completed in 1 sec

running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/PeptideProphetParser
'jagan-J78.pepprophet.xml' MINPROB=0.05 EXTRAITRS=20
-t#-Njagan-J78.pepprophet.xml_-p0.05_-l7_-x20_-O_jagan-J78.pep.xml"
running regression test on basis file
jagan-J78.pepprophet.xml.peptideProphet.-Njagan-J78.pepprophet.xml_-p0.05_-l7_-x20_-O_jagan-J78.pep.xml.tagList
 (X! Tandem (k-score))
init with X! Tandem (k-score) trypsin
MS Instrument info: Manufacturer: Thermo Scientific, Model: LTQ Orbitrap,
Ionization: nanoelectrospray, Analyzer: orbitrap, Detector: inductive
detector

 PeptideProphet  (TPP v4.4 JETSTREAM (unstable development prerelease) rev
0, Build 201006041141 (linux)) akel...@isb
 read in 1127 1+, 1355 2+, 361 3+, 54 4+, 0 5+, 0 6+, and 0 7+ spectra.
Initialising statistical models ...
negmean = -0.490485
negmean = -0.0225753
negmean = -0.520051
negmean = 0.801738
negmean = -0.2
negmean = -0.2
negmean = -0.2
Iterations: .........10.........20........
WARNING: Mixture model quality test failed for charge (1+).
model complete after 29 iterations
different tag count: 718 vs 19620
<error_point error="0.001" min_prob="0.998" num_corr="32" num_incorr="0"/>
        does not agree with expected value
<error_point error="0.010" min_prob="0.96" num_corr="187" num_incorr="2"/>
        at "error" in tag #30 at line 30
        regression test FAILURE in PeptideProphet (see file
PeptideProphet.bad.tagList)
                command completed in 0 sec

running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/ProphetModels.pl -i
jagan-J78.pepprophet.xml"
Analyzing jagan-J78.pepprophet.xml ...
Parsing search results "jagan-J77 (X! Tandem (k-score))"...
  => Total of 0 hits.
Could not find/open font when opening font "arial", using internal
non-scalable font
Warning: empty y range [0:0], adjusting to [0:1]
Could not find/open font when opening font "arial", using internal
non-scalable font

plot "jagan-J78.pepprophet_PPPROB.tsv" using 2:1 title "PeptideProphet" with
line  lc 2  , x notitle with line lt 0 lc -1

^
"jagan-J78.pepprophet_PPPROB.gp", line 16: warning: Skipping data file with
no valid points
Could not find/open font when opening font "arial", using internal
non-scalable font

plot "jagan-J78.pepprophet_IPPROB.tsv" using 2:1 title "iProphet" with line
lc 2  , x notitle with line lt 0 lc -1

^
"jagan-J78.pepprophet_IPPROB.gp", line 16: warning: Skipping data file with
no valid points
command completed in 1 sec

running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/DatabaseParser
'jagan-J78.pepprophet.xml'"
command completed in 0 sec

running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/RefreshParser
'jagan-J78.pepprophet.xml'
'/home/APCF/databases/SwissProt/uniprot_sprot.fasta'
-t#-Njagan-J78.pepprophet.xml_-p0.05_-l7_-x20_-O_jagan-J78.pep.xml"
running regression test on basis file
jagan-J78.pepprophet.xml.RefreshParser.-Njagan-J78.pepprophet.xml_-p0.05_-l7_-x20_-O_jagan-J78.pep.xml.tagList
  - Building Commentz-Walter keyword tree...  - Searching the tree...
  - Linking duplicate entries...  - Printing results...

different tag count: 1 vs 2184
        regression test FAILURE in RefreshParser (see file
RefreshParser.bad.tagList)
                command completed in 2 sec

running: "/mnt/sanfs/APCF/APCF_WEB/tpp/cgi-bin/PepXMLViewer.cgi -I
/mnt/sanfs/APCF/results/tpp/2010-06-23/jagan-J78.pepprophet.xml"

command "/mnt/sanfs/APCF/APCF_WEB/tpp/cgi-bin/PepXMLViewer.cgi -I
/mnt/sanfs/APCF/results/tpp/2010-06-23/jagan-J78.pepprophet.xml" exited with
non-zero exit code: 11
QUIT - the job is incomplete
[r...@apcf-hn3 2010-06-23]#


On Thu, Jun 24, 2010 at 1:39 AM, Brian Pratt <[email protected]>wrote:

> If you're running this using xinteract, you can debug a little by adding
> "-t!" to the xinteract commandline on the release version, and "-t#" to the
> commandline for the development version.  "-t!" (note the exclamation point)
> causes a series of test files to be generated (they're just copies of the
> output as the job progresses) and "-t#" causes the software to check its
> progress against those files.  This may help you figure out where things are
> going wrong.
>
>
> On Wed, Jun 23, 2010 at 12:28 AM, Jagan Kommineni <
> [email protected]> wrote:
>
>> Dear All,
>>
>>            When I run the TPP pipeline with downloaded version of the
>> development prerelease of TPP dated 22-04-2010, I am getting 0 hits
>> whereas when I run pipeline with release version of TPP (TPP v4.3
>> (jetstream)  rev 1) for the same data and parameters, I am getting 822
>> hits.
>>
>>
>> ------------------------------------------------------------------------------------------------------------------------------------------------------------------
>>            Here is the STDOUT when I run the TPP pipeline with
>> development version downloaded on 22-04-2010
>>
>> ----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>> /home/APCF/tpp/bin/xinteract (TPP v4.4 JETSTREAM (unstable development
>> prerelease) rev 0, Build 201006041141 (linux))
>>
>> running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/InteractParser 'jagan-
>> J78.pepprophet.xml' 'jagan-J78.pep.xml' -L'7'"
>>
>> file 1: jagan-J78.pep.xml
>>
>> processed altogether 3429 results
>>
>> results written to file /mnt/sanfs/APCF/results/tpp/2010-06-23/jagan-
>> J78.pepprophet.shtml
>>
>> command completed in 1 sec
>>
>> running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/PeptideProphetParser 'jagan-
>> J78.pepprophet.xml' MINPROB=0.05 EXTRAITRS=20"
>>
>> (X! Tandem (k-score))
>>
>> init with X! Tandem (k-score) trypsin
>>
>> MS Instrument info: Manufacturer: Thermo Scientific, Model: LTQ
>> Orbitrap, Ionization: nanoelectrospray, Analyzer: orbitrap, Detector:
>> inductive detector
>>
>> Initialising statistical models ...
>>
>> Iterations: .........10.........20........
>>
>> model complete after 29 iterations
>>
>> command completed in 0 sec
>>
>> running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/ProphetModels.pl -i jagan-
>> J78.pepprophet.xml"
>>
>> Analyzing jagan-J78.pepprophet.xml ...
>>
>> Parsing search results "jagan-J77 (X! Tandem (k-score))"...
>>
>> => Total of 0 hits.
>>
>> command completed in 0 sec
>>
>> running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/DatabaseParser 'jagan-
>> J78.pepprophet.xml'"
>>
>> command completed in 0 sec
>>
>> running: "/mnt/sanfs/APCF/APCF_WEB/tpp/bin/RefreshParser 'jagan-
>> J78.pepprophet.xml' '/home/APCF/databases/SwissProt/
>> uniprot_sprot.fasta'"
>>
>> - Searching the tree...
>>
>> - Linking duplicate entries... - Printing results...
>>
>> command completed in 3 sec
>>
>> running: "/mnt/sanfs/APCF/APCF_WEB/tpp/cgi-bin/PepXMLViewer.cgi -I /
>> mnt/sanfs/APCF/results/tpp/2010-06-23/jagan-J78.pepprophet.xml"
>>
>> command "/mnt/sanfs/APCF/APCF_WEB/tpp/cgi-bin/PepXMLViewer.cgi -I /mnt/
>> sanfs/APCF/results/tpp/2010-06-23/jagan-J78.pepprophet.xml" exited
>> with non-zero exit code: 11
>>
>> QUIT - the job is incomplete
>>
>> ProteinProphet (C++) by Insilicos LLC and LabKey Software, after the
>> original Perl by A. Keller (TPP v4.4 JETSTREAM (unstable development
>> prerelease) rev 0, Build 201006041141 (linux))
>>
>> (xml input) (report Protein Length) (using degen pep info)
>>
>> . . . reading in /mnt/sanfs/APCF/results/tpp/2010-06-23/jagan-
>> J78.pepprophet.xml. . .
>>
>> did not find any PeptideProphet results in input data! Did you forget
>> to run PeptideProphet?
>>
>> . . . read in 0 1+, 0 2+, 0 3+, 0 4+, 0 5+, 0 6+, 0 7+ spectra with
>> min prob 0.05
>>
>> no data - quitting
>>
>> ==============================================================================
>> But when I run the same thing with release version of TPP (TPP v4.3
>> (jetstream) rev 1) everything  went OK.
>> Here is the STDOUT message ....
>>
>> ---------------------------------------------------------------------------------------------------------------------------------------------------------------
>>
>> [r...@compute-3-0 temp]# pwd
>> /mnt/sanfs/APCF/results/tpp/2010-06-23/temp
>> [r...@compute-3-0 temp]# ls
>> jagan-J77.mzXML  jagan-J77.xml
>> [r...@compute-3-0 temp]# /share/apps/TPP431/trans_proteomic_pipeline/
>> build/linux/Tandem2XML jagan-J77.xml jagan-J78.pep.xml
>> [r...@compute-3-0 temp]# /share/apps/TPP431/trans_proteomic_pipeline/
>> build/linux/InteractParser jagan-J78.pepprophet.xml jagan-J78.pep.xml -
>> L7
>>  file 1: jagan-J78.pep.xml
>>  processed altogether 3429 results
>>
>>  results written to file /mnt/sanfs/APCF/results/tpp/2010-06-23/temp/
>> jagan-J78.pepprophet.shtml
>>
>> [r...@compute-3-0 temp]# /share/apps/TPP431/trans_proteomic_pipeline/
>> build/linux/PeptideProphetParser jagan-J78.pepprophet.xml MINPROB=0.05
>> EXTRAITRS=20
>>  (X! Tandem (k-score))
>> init with X! Tandem (k-score) trypsin
>> MS Instrument info: Manufacturer: Thermo Scientific, Model: LTQ
>> Orbitrap, Ionization: nanoelectrospray, Analyzer: orbitrap, Detector:
>> inductive detector
>>
>>  PeptideProphet  (TPP v4.3 JETSTREAM rev 1, Build 201003241044
>> (linux)) akel...@isb
>>  read in 1127 1+, 1355 2+, 361 3+, 54 4+, 0 5+, 0 6+, and 0 7+
>> spectra.
>> Initialising statistical models ...
>> negmean = -0.490485
>> negmean = -0.0225753
>> negmean = -0.520051
>> negmean = 0.801738
>> negmean = -0.2
>> negmean = -0.2
>> negmean = -0.2
>> Iterations: .........10.........20........
>> WARNING: Mixture model quality test failed for charge (1+).
>> model complete after 29 iterations
>> [r...@compute-3-0 temp]# /share/apps/TPP431/trans_proteomic_pipeline/
>> build/linux/ProphetModels.pl -i jagan-J78.pepprophet.xml
>> Analyzing jagan-J78.pepprophet.xml ...
>> Parsing search results "jagan-J77 (X! Tandem (k-score))"...
>>  => Total of 822 hits.
>> [r...@compute-3-0 temp]# /share/apps/TPP431/trans_proteomic_pipeline/
>> build/linux/DatabaseParser jagan-J78.pepprophet.xml
>> /home/APCF/databases/SwissProt/uniprot_sprot.fasta
>> [r...@compute-3-0 temp]# /share/apps/TPP431/trans_proteomic_pipeline/
>> build/linux/RefreshParser jagan-J78.pepprophet.xml /home/APCF/
>> databases/SwissProt/uniprot_sprot.fasta
>>  - Building Commentz-Walter keyword tree...  - Searching the tree...
>>  - Linking duplicate entries...  - Printing results...
>> [r...@compute-3-0 temp]#
>>
>> ==============================================================================
>>
>> I wonder whether there is any quick fix to this problem. Something
>> broken from the release version to development version.
>>
>> with regards,
>>
>> Jagan Kommineni
>>
>>
>>
>>
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-- 
Dr. Jagan Kommineni
Ludwig Institute for Cancer research
Pakville VIC 3145
Australia.

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