I have been having a problem with TPP in which ProteinProphet would
error out with the response that there are no peptides identified with
a probability greater than 0.05, despite the observation that there
are many peptides passing the threshold in the pepXML file.  This
seems to be a common error due to the frequency with which it is
discussed.  I was able to solve the problem by adding a dbase folder
to the working directory and placing the Mascot .fasta file with the
sequence database.  I also changed the permissions of this folder and
the permissions of the working directory using the command line
described in the TPP tutorial.

Ex: chmod -R 777 C:\Inetpub\tpp-bin\users\tutorial

Once I made these changes the analysis completed smoothly.

-- 
You received this message because you are subscribed to the Google Groups 
"spctools-discuss" group.
To post to this group, send email to [email protected].
To unsubscribe from this group, send email to 
[email protected].
For more options, visit this group at 
http://groups.google.com/group/spctools-discuss?hl=en.

Reply via email to