We still use Qualscore on linux. I've had problems running it on
Apple's OS (I have no explanation why).

my 'qualscore' folder contains:
qualscore_v1.0_2.jar
lib

The 'lib' folder must be in the same folder as the JAR file in order
for qualscore.jar to run.
Alternatively you could write a quick bash script to reduce on
typing.

I have successfully used Qualscore with Sequest results and Mascot
results. However we mostly use XTANDEM in our lab.

When you run xinteract do you use the '-p0' option? (that' -
p<the_number_zero>). This is essential for qualscore to work.
Also, check the version of java you are using. I think you HAVE to use
Oracle's version of JAVA. The some of the other flavors of JAVA won't
work.

I've gotten the error messages above before but I can't remember the
reason. If using the -p0 option doesn't solve it, can you send me one
of your results files and the mzXML file that goes with it?

Hope this helps.

Damian


On Oct 23, 3:22 pm, "[email protected]" <[email protected]> wrote:
> We still use this tool from time to time. I will ask Damian in my
> group to take a look at this post to see if he can identify the
> problem.
>
> Alexey Nesvizhskii
> University of Michigan
>
> On Oct 8, 10:41 am, Bjorn <[email protected]> wrote:
>
> > I tried to get Qualscore to work on the Mac command line, but got
> > this
>
> > bvictor$ java -jar /usr/local/tpp/bin/qualscore.v1.0_2.jar
> > P01080_24h_gamma_decoy_cRAP.pep.xml
> > QualScore version 1.0_2 Copyright (C) 2006
> > Institute for Systems Biology, Seattle WA
> > QualScore is free software and comes with absolutely no warranty.
>
> > XML
> > Loading interact data:
> >   857
> > Interact data file contains 856 entries.
> > 12 +1 were removed.
> > Enumerating scans:
> >   processing 100920.mzXML...Problem finding offset index.
> > java.io.FileNotFoundException: /Library/WebServer/Documents/thegpm/tpp/
> > data/P01080_Zambia5/CID/100920.mzXML (No such file or directory)
> >         at java.io.FileInputStream.open(Native Method)
> >         at java.io.FileInputStream.<init>(FileInputStream.java:106)
> >         at 
> > org.isb.mzxml.MzXMLParser.getScanOffsetIndex(MzXMLParser.java:164)
> >         at org.isb.mzxml.MzXML.<init>(MzXML.java:50)
> >         at
> > org.systemsbiology.qualscore.SingleInteractXML.enumerateDtasFromMZXML(SingleInteractXML.java:
> > 85)
> >         at
> > org.systemsbiology.qualscore.SingleInteractXML.enumerateScans(SingleInteractXML.java:
> > 71)
> >         at org.systemsbiology.qualscore.commandline.Main.<init>(Main.java:
> > 197)
> >         at 
> > org.systemsbiology.qualscore.commandline.Main.main(Main.java:1041)
> > error: Parse error occurred - /Library/WebServer/Documents/thegpm/tpp/
> > data/P01080_Zambia5/CID/100920.mzXML (No such file or directory)
> > java.io.FileNotFoundException: /Library/WebServer/Documents/thegpm/tpp/
> > data/P01080_Zambia5/CID/100920.mzXML (No such file or directory)
> >         at java.io.FileInputStream.open(Native Method)
> >         at java.io.FileInputStream.<init>(FileInputStream.java:106)
> >         at java.io.FileInputStream.<init>(FileInputStream.java:66)
> >         at
> > sun.net.www.protocol.file.FileURLConnection.connect(FileURLConnection.java:
> > 70)
> >         at
> > sun.net.www.protocol.file.FileURLConnection.getInputStream(FileURLConnection....
> > 161)
> >         at
> > com.sun.org.apache.xerces.internal.impl.XMLEntityManager.setupCurrentEntity(XMLEntityManager.java:
> > 653)
> >         at
> > com.sun.org.apache.xerces.internal.impl.XMLVersionDetector.determineDocVersion(XMLVersionDetector.java:
> > 186)
> >         at
> > com.sun.org.apache.xerces.internal.parsers.XML11Configuration.parse(XML11Configuration.java:
> > 772)
> >         at
> > com.sun.org.apache.xerces.internal.parsers.XML11Configuration.parse(XML11Configuration.java:
> > 737)
> >         at
> > com.sun.org.apache.xerces.internal.parsers.XMLParser.parse(XMLParser.java:
> > 119)
> >         at
> > com.sun.org.apache.xerces.internal.parsers.AbstractSAXParser.parse(AbstractSAXParser.java:
> > 1205)
> >         at com.sun.org.apache.xerces.internal.jaxp.SAXParserImpl
> > $JAXPSAXParser.parse(SAXParserImpl.java:522)
> >         at javax.xml.parsers.SAXParser.parse(SAXParser.java:395)
> >         at javax.xml.parsers.SAXParser.parse(SAXParser.java:331)
> >         at org.isb.mzxml.MzXMLParser.getScans(MzXMLParser.java:128)
> >         at org.isb.mzxml.MzXML.rapScans(MzXML.java:132)
> >         at
> > org.systemsbiology.qualscore.SingleInteractXML.enumerateDtasFromMZXML(SingleInteractXML.java:
> > 91)
> >         at
> > org.systemsbiology.qualscore.SingleInteractXML.enumerateScans(SingleInteractXML.java:
> > 71)
> >         at org.systemsbiology.qualscore.commandline.Main.<init>(Main.java:
> > 197)
> >         at 
> > org.systemsbiology.qualscore.commandline.Main.main(Main.java:1041)
> > Exception in thread "main" java.lang.NullPointerException
> >         at
> > org.systemsbiology.qualscore.SingleInteractXML.enumerateDtasFromMZXML(SingleInteractXML.java:
> > 93)
> >         at
> > org.systemsbiology.qualscore.SingleInteractXML.enumerateScans(SingleInteractXML.java:
> > 71)
> >         at org.systemsbiology.qualscore.commandline.Main.<init>(Main.java:
> > 197)
> >         at 
> > org.systemsbiology.qualscore.commandline.Main.main(Main.java:1041)
>
> > somewhere in the beginning I see this:
> > FileNotFoundException: /Library/WebServer/Documents/thegpm/tpp/data/
> > P01080_Zambia5/CID/100920.mzXML (No such file or directory)
>
> > This file does indeed not exist. There are many files for the pep.xml
> > file and they are all called something like this:
> > 100920.LC6.IT6.XX.P01080_2-A.10_01_2701.mzXML
> > 100920.LC6.IT6.XX.P01080_2-A.11_01_2702.mzXML
> > etc...
>
> > Is that where Qualscore is tripping over?
>
> > To be honest, I still don't know where I am supposed to put the lib
> > folder and qualscore.v1.0_2.jar file. I just tried something...
> > Can anyone please tell me where they store the lib and
> > qualscore.v1.0_2.jar file on a Mac system??
>
> > Many thanks!
>
> > bjorn

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