almost a month has pased since I posted this, maybe it has been
discussed before.
can somebody light me up with the link to the previous post?
or
just tell me how to eliminate the "ERROR: there was a problem with
filterMRM: 9 "?

Thank you for all your time and attention!

On 4月29日, 下午9时31分, jun <[email protected]> wrote:
> Hi everyone, I am just a beginner in MRM and my first step end up in
> mud.
>
> I am using TPP ver4.4.1 vuvuzela and downloaded the 18 protein MaRiMba
> tutorial files. I followed the instructions in the pdf files attached
> with the tutorial files, then I saw the red "FAILED". According to the
> log message, there is an error 9 with filterMRM. I did monor change to
> the criteria used for filter and still could not get my first MRM
> list.
>
> I attach the log message here and hope for your advices.
>
> Thank you all!
>
> Run MaRiMba started at: Fri Apr 29 21:09:22 2011
> ...Refreshing library against database
> ...Filtering out non-proteotypic and unmapped peptides
> SpectraST started at Fri Apr 29 21:09:23 2011.
> Creating library from "c:/Inetpub/wwwroot/ISB/data/MaRiMba/
> 18mix_Mix7_Raw.splib"
> REFRESHING protein mappings...DONE!
> Importing peptide ions...500...1000...DONE!
>
> Library file (BINARY) "tmp_refreshed.splib" created.
> Library file (TEXT) "tmp_refreshed.sptxt" created.
> M/Z Index file "tmp_refreshed.spidx" created.
> Peptide Index file "tmp_refreshed.pepidx" created.
>
> Total number of spectra in library: 11679
> Total number of distinct peptide ions in library: 1107
> Total number of distinct stripped peptides in library: 811
>
> CHARGE            +1: 0 ; +2: 3742 ; +3: 4512 ; +4: 2591 ; +5: 834 ; >
> +5: 0
> TERMINI           Tryptic: 10334 ; Semi-tryptic: 1333 ; Non-tryptic:
> 12
> PROBABILITY       >0.9999: 5618 ; 0.999-0.9999: 2753 ; 0.99-0.999:
> 1875 ; 0.9-0.99: 1432 <0.9: 1
>
> ...skipping 76 lines of output...
>
> Library file (BINARY) "tmp_MRM.splib" created.
> Library file (TEXT) "tmp_MRM.sptxt" created.
> M/Z Index file "tmp_MRM.spidx" created.
> Peptide Index file "tmp_MRM.pepidx" created.
> MRM Table file "tmp_MRM.mrm" created.
>
> Total number of spectra in library: 118
> Total number of distinct peptide ions in library: 118
> Total number of distinct stripped peptides in library: 88
>
> CHARGE            +1: 0 ; +2: 75 ; +3: 34 ; +4: 8 ; +5: 1 ; >+5: 0
> TERMINI           Tryptic: 118 ; Semi-tryptic: 0 ; Non-tryptic: 0
> PROBABILITY       >0.9999: 87 ; 0.999-0.9999: 15 ; 0.99-0.999: 11 ;
> 0.9-0.99: 5 <0.9: 0
> NREPS             20+: 28 ; 10-19: 26 ; 4-9: 44 ; 2-3: 11 ; 1: 9
> MODIFICATIONS     C,Carbamidomethyl: 36
>
> Total Run Time = 0 seconds.
> SpectraST finished at Fri Apr 29 21:12:16 2011 without error.
> ...Applying user-defined fiters
> ERROR: there was a problem with filterMRM: 9
>
> Command FAILED

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