Hi, I came across this quote recently: "PeptideProphet supplemented this parametric model with a variable component mixture model and a semi-parametric model that incorporate decoy database results...the Mascot implementation does not improve discrimination and only uses the raw Mascot scores".
Is this true? In my experience, using Prophet's semi-parametric model can significantly increase peptide sensitivity for Mascot results. Thanks, John -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To post to this group, send email to [email protected]. To unsubscribe from this group, send email to [email protected]. For more options, visit this group at http://groups.google.com/group/spctools-discuss?hl=en.
