Hey Brian,

I am not sure what change broke your analysis and is causing the issue you
have.  To track this I will need to access your files and trace the code.
Can you post your files somewhere I can get to them?

Thanks,
-David

On Fri, Aug 31, 2012 at 2:37 PM, Brian Hampton <[email protected]> wrote:

> Nothing I have tried has allowed me to quantitate using ASAPRatio in
> version 4.6 (Win7).  So I switched back to 4.5.2 on Ubuntu 10.10 using the
> same data set, database, and parameter files and I get nice quantitation.
>
> Here is the relevant part of the log from 4.5.2.
>
> running: "/usr/local/apps/tpp/bin/ASAPRatioPeptideParser 
> 'HL-interact.pep.xml.gz' -lnK -b -F -C -r0.5 -S"
> K 170.142 176.18
> n 43.0548 49.0924
> static heavy label for file 
> /usr/local/apps/tpp/data/projects/S_Aorta/qc/H-120827_S-Aorta_GuanidineExtract-RABA-QC01.mzXML
> static light label for file 
> /usr/local/apps/tpp/data/projects/S_Aorta/qc/L-120827_S-Aorta_GuanidineExtract-RABA-QC01.mzXML
> command completed in 20 sec
>
>
> In TPP 4.6, the two files are not read in at all and it throws an error 
> saying multiple modifications on n are not allowed and the analysis stops.
>
>
> If anyone has successfully used ASAPRatio in TPP 4.6 to quantitate amine 
> reactive chemical labeling with stable isotopes I would like to hear how you 
> set up the pipeline to get ASAPRatio to actually work correctly.
>
>
> Thanks in advance,
>
>
> Brian
>
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