Hi all

I haven't found an answer to my question on this Group or the
SpectraST wiki. Thus, I suspect the answer is 'no' but if not, I'm
hoping someone here can tell me.

The question is, if the spectra for a particular isotopically labelled
form of a peptide does not exist in the spectral library but a
differently labelled form does, can/does SpectraST adapt the spectra
to what would be expected? For example, if LLAGTK (no label) exists in
the spectral library but you have a SILAC-labelled sample (with normal
Lys and D4-Lys) containing LLAGTK, can the algorithm do two searches,
one a direct comparison and the second where all Y-ions are shifted by
4 Da?

Thanks

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