There’s also a recent paper that describes such a strategy:


http://pubs.acs.org/doi/abs/10.1021/pr300561q







*From:* [email protected] [mailto:
[email protected]] *On Behalf Of *Brian Pratt
*Sent:* Tuesday, January 08, 2013 8:46 AM
*To:* [email protected]
*Subject:* Re: [spctools-discuss] Re: splitting large files (via msconvert?)



Not sure how helpful an answer this is, but (as you perhaps already know)
there are several parallelized versions of X!Tandem that do that for you.



Brian

On Tue, Jan 8, 2013 at 1:59 AM, Gautam Saxena <[email protected]> wrote:

FYI: I meant to write "MB" wherever I wrote "GB".



On Tuesday, 8 January 2013 04:56:01 UTC-5, Gautam Saxena wrote:

Bonus: Similarily, is there a way to break it up in "n" file sizes so that
very roughly they correspond to certain sizes (eg 100 GB) each? Thus, if
one MS file was say ~220 GB, it would be split into 2 files of roughtly
~100GB; but if another MS files were ~540 GB, it would be split into 5
files of roughly ~100GB.

On Tuesday, 8 January 2013 04:26:14 UTC-5, Gautam Saxena wrote:

I have some large MS raw files (eg 500 GB or greater). I'd like to ideally
split it into "n" mzXML files of roughly the same size so that each
X!Tandem process takes roughly the same amount of time. Is there a way to
accomplish this elegantly using msconvert or some other technique? (For
now, the MS files are Thermo raw files; however, they may be other MS
vendor formats that we can convert to mzXML using msconvert or we may have
the mzXML file itself as a starting point.)



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