Yes, and the mzXML decomposer is available here: 
http://www.ms-utils.org/decomposition/. Please let us know if you encounter 
some problems running it.

~Magnus

On Tuesday, 8 January 2013 17:57:40 UTC+1, Eric Deutsch wrote:
>
> There’s also a recent paper that describes such a strategy:
>
>  
>
> http://pubs.acs.org/doi/abs/10.1021/pr300561q
>
>  
>
>  
>
>  
>
> *From:* [email protected] <javascript:> [mailto:
> [email protected] <javascript:>] *On Behalf Of *Brian Pratt
> *Sent:* Tuesday, January 08, 2013 8:46 AM
> *To:* [email protected] <javascript:>
> *Subject:* Re: [spctools-discuss] Re: splitting large files (via 
> msconvert?)
>
>  
>
> Not sure how helpful an answer this is, but (as you perhaps already know) 
> there are several parallelized versions of X!Tandem that do that for you.
>
>  
>
> Brian
>
> On Tue, Jan 8, 2013 at 1:59 AM, Gautam Saxena 
> <[email protected]<javascript:>> 
> wrote:
>
> FYI: I meant to write "MB" wherever I wrote "GB".
>
>
>
> On Tuesday, 8 January 2013 04:56:01 UTC-5, Gautam Saxena wrote:
>
> Bonus: Similarily, is there a way to break it up in "n" file sizes so that 
> very roughly they correspond to certain sizes (eg 100 GB) each? Thus, if 
> one MS file was say ~220 GB, it would be split into 2 files of roughtly 
> ~100GB; but if another MS files were ~540 GB, it would be split into 5 
> files of roughly ~100GB. 
>
> On Tuesday, 8 January 2013 04:26:14 UTC-5, Gautam Saxena wrote:
>
> I have some large MS raw files (eg 500 GB or greater). I'd like to ideally 
> split it into "n" mzXML files of roughly the same size so that each 
> X!Tandem process takes roughly the same amount of time. Is there a way to 
> accomplish this elegantly using msconvert or some other technique? (For 
> now, the MS files are Thermo raw files; however, they may be other MS 
> vendor formats that we can convert to mzXML using msconvert or we may have 
> the mzXML file itself as a starting point.)
>
>  
>
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