Hello Heeyoun,
Depending on the system you are on, you could be running into a native file
size limit of 2Gb.  Or it could be a malformed file; hard to tell without
further information.
Also, make sure that the mzXML file is in the expected location -- and we
would recommend not using any special characters in the file name (such as
parenthesis), especially as part of the name extension (i.e. make sure it
ends in ".mzXML").
Cheers,
--Luis


On Sun, Mar 8, 2015 at 9:52 PM, Heeyoun Hwang <[email protected]> wrote:

> Hi, All
>
> I have tried to search several RAW files with MASCOT and TPP.
> Most files were searched over to protein prophet with no problem.
> but, some .dat files were able to convert to .pep.xml files depends on the
> size of their .mzXML files over 2.1Gb.
> I got same result from the command line and web version (TPP v.4.7)
>
> Welcome to your any advice.
>
>
>
>   Command 9 [Mon Mar 9 13:27:39 2015]       [ Show / Hide ]
> *EXECUTING: cd c:/Inetpub/wwwroot/ISB/data/HBRAINetd&
> c:\Inetpub\tpp-bin\Mascot2XML
> c:/Inetpub/wwwroot/ISB/data/HBRAINetd/20111216_EPT_S1_S2_10_ETD.dat
> -Dc:/Inetpub/wwwroot/ISB/data/HBRAINetd/nextprot_release_20150101.fasta
> -Etrypsin *
>
> filepath: c:/Inetpub/wwwroot/ISB/data/HBRAINetd/, extn: 
> 20111216_EPT_S1_S2_10_ETD
> A stored as 71.0371
> B stored as 114.535
> C stored as 160.031
> D stored as 115.027
> E stored as 129.043
> F stored as 147.068
> G stored as 57.0215
> H stored as 137.059
> I stored as 113.084
> J stored as 0
> K stored as 128.095
> L stored as 113.084
> M stored as 131.04
> N stored as 114.043
> O stored as 0
> P stored as 97.0528
> Q stored as 128.059
> R stored as 156.101
> S stored as 87.032
> T stored as 101.048
> U stored as 150.954
> V stored as 99.0684
> W stored as 186.079
>
>
>
> X stored as 111
> Y stored as 163.063
> Z stored as 128.551
> c stored as 17.0027
> n stored as 1.00783
> variable modification 1, delta mass 42.0106 for Acetyl (K):
>  residues: K
>  nterm: 0
>  cterm: 0
>  protterm: 0
>
> variable modification 2, delta mass 15.9949 for Oxidation (M):
>  residues: M
>  nterm: 0
>  cterm: 0
>  protterm: 0
>
> c:/Inetpub/wwwroot/ISB/data/HBRAINetd/20111216_EPT_S1_S2_10_ETD.mzXML(1) : 
> error 4: Syntax error parsing XML.
>
>
> *Command FAILED*
> RETURN CODE:63744
>
>
> thanx and regards.
>
> Heeyoun Hwang.
>
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