Hi,
I have been installed TPP4.8.0 on Windows 7. Unfortunately I had no success 
yet for processing MS-GF+ files. The error I am seeing is the following:

*command "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml" 
MINPROB=0.05 PPM" exited with non-zero exit code: -1073741819*

Not quite sure how I can get TPP to smoothly process the Ms-GF+ files. Any 
advice is greatly appreciated. 
HFaz

On Friday, July 24, 2015 at 8:35:57 PM UTC-4, Jesse wrote:
>
> David, Joseph, 
>
> Awesome everything works now with version 4.8.0  
>
> Thank you!
> Jesse
>
> On Friday, July 24, 2015 at 2:33:05 PM UTC-7, David Shteynberg wrote:
>>
>> Hello Jesse,
>>
>>
>> I think the issue is that ProteinProphet may not be finding the database 
>> used in the search.  Can you run RefreshParser on the commandline as 
>> follows:
>>
>> RefreshParser 
>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Kac.GluC.all.interact.pep.xml 
>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Ecoli.fasta
>>
>> Then try to rerun ProteinProphet on the commandline
>>
>> ProteinProphet 
>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Kac.GluC.all.interact.pep.xml 
>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Kac.GluC.all.interact.prot.xml 
>>  XML
>>
>>
>> Let me know if you see any errors.
>>
>> Thank you,
>> -David
>>
>> On Fri, Jul 24, 2015 at 2:19 PM, Joseph Slagel <
>> [email protected]> wrote:
>>
>>> Jesse,
>>>
>>> Yes, I think David pinpointed an issue.   It appears as if you 
>>> downloaded a developer alpha build of TPP.  As an alpha build, its expected 
>>> to have lots of problems as it gets tested and they get fixed.  I'd 
>>> recommend downloading the latest stable TPP release, 4.8.0,  from 
>>> sourceforge,  
>>> http://sourceforge.net/projects/sashimi/files/latest/download?source=files
>>>
>>> -Joe
>>>
>>>
>>> On Fri, Jul 24, 2015 at 2:11 PM, David Shteynberg <
>>> [email protected]> wrote:
>>>
>>>> Hi Jesse, 
>>>>
>>>> This issue seems unrelated to the issue that I just corrected in 
>>>> InteractParser.
>>>>
>>>> It appears that on your system everything is installed to C:\TPP\bin 
>>>> whereas it should install to C:\Inetpub\tpp-bin. Are you perhaps Which 
>>>> version are you installing?  Can you try this command in the commandline 
>>>> to 
>>>> see if it gives you any additional messages? 
>>>>
>>>> Thank you,
>>>>
>>>> -David
>>>>
>>>> On Fri, Jul 24, 2015 at 1:15 PM, Jesse <[email protected]> wrote:
>>>>
>>>>> Hi David,
>>>>>
>>>>> Now I'm almost certain there is a problem with the installation on my 
>>>>> new systems.  TPP wont even convert RAW files or download spectral 
>>>>> libraries.  Any suggestions about where to start?
>>>>>
>>>>> *EXECUTING: C:/TPP/bin/msconvert 
>>>>> c:/Inetpub/wwwroot/ISB/data/dbase/OR20080317_S_SILAC-LH_1-1_01.RAW -v 
>>>>> --mzXML -o c:/Inetpub/wwwroot/ISB/data/dbase --filter "peakPicking true 
>>>>> [1,2]" *
>>>>>
>>>>> *Command FAILED*
>>>>> RETURN CODE:13568
>>>>>
>>>>> Best,
>>>>> Jesse
>>>>>
>>>>> On Thursday, July 23, 2015 at 2:01:02 PM UTC-7, Jesse wrote:
>>>>>>
>>>>>> Hi David,
>>>>>>
>>>>>> I just sent you a link to the files with my new email address.  I 
>>>>>> tried without the pI model and I got the same error.  I suspect a 
>>>>>> problem 
>>>>>> with the network settings on the computers at work.  
>>>>>>
>>>>>> Thanks for looking into this for me.  
>>>>>>
>>>>>> Best,
>>>>>> Jesse
>>>>>> ------------------------------
>>>>>> *From:* [email protected] [[email protected]] 
>>>>>> on behalf of David Shteynberg [[email protected]]
>>>>>>
>>>>>> *Sent:* Thursday, July 23, 2015 11:58 AM
>>>>>> *To:* spctools-discuss
>>>>>> *Subject:* Re: [spctools-discuss] Re: Processing MSGF+ searches
>>>>>>
>>>>>> Hello Jesse, 
>>>>>>
>>>>>>
>>>>>> I am not sure that I can pinpoint the error without access to your 
>>>>>> file. Is this possible?  Otherwise you can try the analysis with the 
>>>>>> following PeptideProphetParser options removing PI model which has not 
>>>>>> been 
>>>>>> extensively tested through MSGF+ and could be the culprit.
>>>>>>
>>>>>> PeptideProphetParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.0 
>>>>>> CLEVEL=2.5 
>>>>>> PPM DECOYPROBS ACCMASS NONTT NONPARAM DECOY=XXX_ IGNORECHG=1
>>>>>>
>>>>>> If this works then the problem is with the pI model. 
>>>>>>
>>>>>> Let me know if you can forward me your test.interact.pep.xml file to 
>>>>>> test with.
>>>>>>
>>>>>> Thank you,
>>>>>> -David
>>>>>>
>>>>>> On Wed, Jul 22, 2015 at 7:57 PM, Jesse <[email protected]> wrote:
>>>>>>
>>>>>>> Hi David, 
>>>>>>>
>>>>>>> I'm having problems recently running PeptideProphet on MSGF+ search 
>>>>>>> output of GluC digests.  I tried the perl script you suggest but I'm 
>>>>>>> not 
>>>>>>> sure if it does anything because I'm not sure what it is supposed to 
>>>>>>> do.  
>>>>>>> That line is meant to replace a single "\" with "-", correct?  It seems 
>>>>>>> to 
>>>>>>> start OK but then it quits. The GUI then prints return code: 65280.  If 
>>>>>>> you could make a quick suggestion as to whether you think the problem 
>>>>>>> is my 
>>>>>>> pep.xml files again or my install I would greatly appreciate it.  I 
>>>>>>> tried 
>>>>>>> both the development release and 4.8. 
>>>>>>>
>>>>>>> C:/TPP/bin/xinteract (TPP v5.0.0a2 Development, Build xxxx-xxxx 
>>>>>>> (x86_64))
>>>>>>>  PPM mode in Accurate Mass Model ...
>>>>>>>  PPM mode in Accurate Mass Model ...
>>>>>>>
>>>>>>> running: "C:/TPP/bin/InteractParser 
>>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" 
>>>>>>> "150624_0002_CR1_GluC_Xyl_0p4_rep1b.pep.XML" 
>>>>>>> "150624_0003_CR1_GluC_Xyl_4_rep1.pep.XML" 
>>>>>>> "150624_0004_CR1_GluC_Glc_0p4_rep1.pep.XML" 
>>>>>>> "150624_0005_CR1_GluC_Glc_4_rep1.pep.XML" 
>>>>>>> "150624_0007_CR1_GluC_Xyl_0p4_rep2.pep.XML" 
>>>>>>> "150624_0008_CR1_GluC_Xyl_4_rep2.pep.XML" 
>>>>>>> "150624_0009_CR1_GluC_Glc_0p4_rep2.pep.XML" 
>>>>>>> "150624_0010_CR1_GluC_Glc_4_rep2.pep.XML" 
>>>>>>> "150624_0012_CR1_GluC_Xyl_0p4_rep3.pep.XML" 
>>>>>>> "150624_0014_CR1_GluC_Xyl_4_rep3.pep.XML" 
>>>>>>> "150624_0015_CR1_GluC_Glc_0p4_rep3.pep.XML" 
>>>>>>> "150624_0016_CR1_GluC_Glc_4_rep3.pep.XML" -L"7" -E"nonspecific""
>>>>>>>  file 1: 150624_0002_CR1_GluC_Xyl_0p4_rep1b.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 2: 150624_0003_CR1_GluC_Xyl_4_rep1.pep.XMLWARNING: empty raw_data 
>>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 3: 150624_0004_CR1_GluC_Glc_0p4_rep1.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 4: 150624_0005_CR1_GluC_Glc_4_rep1.pep.XMLWARNING: empty raw_data 
>>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 5: 150624_0007_CR1_GluC_Xyl_0p4_rep2.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 6: 150624_0008_CR1_GluC_Xyl_4_rep2.pep.XMLWARNING: empty raw_data 
>>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 7: 150624_0009_CR1_GluC_Glc_0p4_rep2.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 8: 150624_0010_CR1_GluC_Glc_4_rep2.pep.XMLWARNING: empty raw_data 
>>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 9: 150624_0012_CR1_GluC_Xyl_0p4_rep3.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 10: 150624_0014_CR1_GluC_Xyl_4_rep3.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 11: 150624_0015_CR1_GluC_Glc_0p4_rep3.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  file 12: 150624_0016_CR1_GluC_Glc_4_rep3.pep.XMLWARNING: empty 
>>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>>> Failed to open input file 
>>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzML'.WARNING:
>>>>>>>  cannot open data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzML
>>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>> SUCCESS: CORRECTED data file 
>>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzXML
>>>>>>>  in msms_run_summary tag ...
>>>>>>>  processed altogether 186504 results
>>>>>>> INFO: Results written to file: 
>>>>>>> C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml
>>>>>>> command completed in 86 sec 
>>>>>>>
>>>>>>> running: "C:/TPP/bin/DatabaseParser 
>>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml""
>>>>>>> command completed in 2 sec 
>>>>>>>
>>>>>>> running: "C:/TPP/bin/RefreshParser 
>>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" 
>>>>>>> "C:\Jesse\Ecoli.fasta""
>>>>>>>   - Searching the tree...opening "c:/Jesse/Ecoli.fasta" as 
>>>>>>> "c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Ecoli.fasta"
>>>>>>>
>>>>>>>   - Linking duplicate entries...  - Printing results...
>>>>>>>
>>>>>>>   - Building Commentz-Walter keyword tree...command completed in 22 sec 
>>>>>>>
>>>>>>> running: "C:/TPP/bin/PeptideProphetParser 
>>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.05 
>>>>>>> CLEVEL=2.5 PPM PPM ACCMASS PI NONTT NONPARAM DECOY=XXX_ IGNORECHG=1"
>>>>>>> using Accurate Mass Bins
>>>>>>> using PPM mass difference
>>>>>>> using pI
>>>>>>> Using Decoy Label "XXX_".
>>>>>>> Ignoring charge 1+ spectra.
>>>>>>> Not using ntt model
>>>>>>> Using non-parametric distributions
>>>>>>>  (MS-GF+)WARNING: Support of MSGF+ may not be full.  There exist known 
>>>>>>> issues with the way MSGF+ encodes certain modifications in pep.xml that 
>>>>>>> may not be correct. Also, high-scoring DECOY have been observed in 
>>>>>>> MSGF+ analysis.  The user is encouraged to be vigilant in comparing 
>>>>>>> model estimated error-rates to the DECOY-estimated error-rates to make 
>>>>>>> sure the two agree and set CLEVEL parameter accordingly: see 
>>>>>>> http://tools.proteomecenter.org/wiki/index.php?title=TPP:Frequently_Asked_Questions#What_is_CLEVEL_and_when_do_I_use_it.3F
>>>>>>> adding Accurate Mass mixture distr
>>>>>>> adding pI mixture distr
>>>>>>> init with MS-GF+ nonspecific 
>>>>>>>
>>>>>>> command "C:/TPP/bin/PeptideProphetParser 
>>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.05 
>>>>>>> CLEVEL=2.5 PPM PPM ACCMASS PI NONTT NONPARAM DECOY=XXX_ IGNORECHG=1" 
>>>>>>> failed: Unknown error
>>>>>>>
>>>>>>> command "C:/TPP/bin/PeptideProphetParser 
>>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.05 
>>>>>>> CLEVEL=2.5 PPM PPM ACCMASS PI NONTT NONPARAM DECOY=XXX_ IGNORECHG=1" 
>>>>>>> exited with non-zero exit code: 255
>>>>>>> QUIT - the job is incomplete
>>>>>>>
>>>>>>>
>>>>>>> On Thursday, July 9, 2015 at 2:33:16 PM UTC-7, [email protected] 
>>>>>>> wrote: 
>>>>>>>>
>>>>>>>> Hi David,
>>>>>>>>
>>>>>>>> I can cope with the command line. Thanks for the info I never would 
>>>>>>>> have worked that one out...
>>>>>>>>
>>>>>>>> Peter
>>>>>>>>
>>>>>>>> On Thursday, July 9, 2015 at 2:55:41 PM UTC+10, [email protected] 
>>>>>>>> wrote: 
>>>>>>>>>
>>>>>>>>> Hi,
>>>>>>>>>
>>>>>>>>>
>>>>>>>>> I want to use the TPP to combine, Mascot, X!Tandem and MSGF+ 
>>>>>>>>> searches (amongst other things). I'm having trouble getting around 
>>>>>>>>> some of 
>>>>>>>>> the basics. I have successfully used the TPP in the past to process 
>>>>>>>>> samples, but only with Mascot data.
>>>>>>>>>
>>>>>>>>> Once I get my MSGF+ output files converted to pepXML I should be 
>>>>>>>>> fine. I cannot work out how I get the MSGF+ files converted. The 
>>>>>>>>> output 
>>>>>>>>> generated by MSGF+ is an mzid file. I am also unclear as to where the 
>>>>>>>>> database (with decoys) and mzXML files, used for searching, need to 
>>>>>>>>> be 
>>>>>>>>> located when generating this pepXML file. I have noticed error 
>>>>>>>>> messages in 
>>>>>>>>> the logs about accessing the database and mzXML file. I am generally 
>>>>>>>>> using 
>>>>>>>>> the Petunia interface as it's much nicer to work with multiple files.
>>>>>>>>>
>>>>>>>>>
>>>>>>>>> Thanks,
>>>>>>>>>
>>>>>>>>>
>>>>>>>>> Peter
>>>>>>>>>
>>>>>>>> -- 
>>>>>>> You received this message because you are subscribed to the Google 
>>>>>>> Groups "spctools-discuss" group.
>>>>>>> To unsubscribe from this group and stop receiving emails from it, 
>>>>>>> send an email to [email protected].
>>>>>>> To post to this group, send email to [email protected].
>>>>>>> Visit this group at http://groups.google.com/group/spctools-discuss.
>>>>>>> For more options, visit https://groups.google.com/d/optout.
>>>>>>>
>>>>>>
>>>>>> -- 
>>>>>> You received this message because you are subscribed to the Google 
>>>>>> Groups "spctools-discuss" group.
>>>>>> To unsubscribe from this group and stop receiving emails from it, 
>>>>>> send an email to [email protected].
>>>>>> To post to this group, send email to [email protected].
>>>>>> Visit this group at http://groups.google.com/group/spctools-discuss.
>>>>>> For more options, visit https://groups.google.com/d/optout.
>>>>>>
>>>>> -- 
>>>>> You received this message because you are subscribed to the Google 
>>>>> Groups "spctools-discuss" group.
>>>>> To unsubscribe from this group and stop receiving emails from it, send 
>>>>> an email to [email protected].
>>>>> To post to this group, send email to [email protected].
>>>>> Visit this group at http://groups.google.com/group/spctools-discuss.
>>>>> For more options, visit https://groups.google.com/d/optout.
>>>>>
>>>>
>>>> -- 
>>>> You received this message because you are subscribed to the Google 
>>>> Groups "spctools-discuss" group.
>>>> To unsubscribe from this group and stop receiving emails from it, send 
>>>> an email to [email protected].
>>>> To post to this group, send email to [email protected].
>>>> Visit this group at http://groups.google.com/group/spctools-discuss.
>>>> For more options, visit https://groups.google.com/d/optout.
>>>>
>>>
>>>
>>>
>>> -- 
>>> Joe Slagel
>>> Institute for Systems Biology
>>> [email protected]
>>>
>>> -- 
>>> You received this message because you are subscribed to the Google 
>>> Groups "spctools-discuss" group.
>>> To unsubscribe from this group and stop receiving emails from it, send 
>>> an email to [email protected].
>>> To post to this group, send email to [email protected].
>>> Visit this group at http://groups.google.com/group/spctools-discuss.
>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>
>>

-- 
You received this message because you are subscribed to the Google Groups 
"spctools-discuss" group.
To unsubscribe from this group and stop receiving emails from it, send an email 
to [email protected].
To post to this group, send email to [email protected].
Visit this group at http://groups.google.com/group/spctools-discuss.
For more options, visit https://groups.google.com/d/optout.

Reply via email to