David, Joseph, 

Awesome everything works now with version 4.8.0  

Thank you!
Jesse

On Friday, July 24, 2015 at 2:33:05 PM UTC-7, David Shteynberg wrote:
>
> Hello Jesse,
>
>
> I think the issue is that ProteinProphet may not be finding the database 
> used in the search.  Can you run RefreshParser on the commandline as 
> follows:
>
> RefreshParser 
> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Kac.GluC.all.interact.pep.xml 
> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Ecoli.fasta
>
> Then try to rerun ProteinProphet on the commandline
>
> ProteinProphet 
> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Kac.GluC.all.interact.pep.xml 
> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Kac.GluC.all.interact.prot.xml 
>  XML
>
>
> Let me know if you see any errors.
>
> Thank you,
> -David
>
> On Fri, Jul 24, 2015 at 2:19 PM, Joseph Slagel <
> [email protected] <javascript:>> wrote:
>
>> Jesse,
>>
>> Yes, I think David pinpointed an issue.   It appears as if you downloaded 
>> a developer alpha build of TPP.  As an alpha build, its expected to have 
>> lots of problems as it gets tested and they get fixed.  I'd recommend 
>> downloading the latest stable TPP release, 4.8.0,  from sourceforge,  
>> http://sourceforge.net/projects/sashimi/files/latest/download?source=files
>>
>> -Joe
>>
>>
>> On Fri, Jul 24, 2015 at 2:11 PM, David Shteynberg <
>> [email protected] <javascript:>> wrote:
>>
>>> Hi Jesse, 
>>>
>>> This issue seems unrelated to the issue that I just corrected in 
>>> InteractParser.
>>>
>>> It appears that on your system everything is installed to C:\TPP\bin 
>>> whereas it should install to C:\Inetpub\tpp-bin. Are you perhaps Which 
>>> version are you installing?  Can you try this command in the commandline to 
>>> see if it gives you any additional messages? 
>>>
>>> Thank you,
>>>
>>> -David
>>>
>>> On Fri, Jul 24, 2015 at 1:15 PM, Jesse <[email protected] <javascript:>> 
>>> wrote:
>>>
>>>> Hi David,
>>>>
>>>> Now I'm almost certain there is a problem with the installation on my 
>>>> new systems.  TPP wont even convert RAW files or download spectral 
>>>> libraries.  Any suggestions about where to start?
>>>>
>>>> *EXECUTING: C:/TPP/bin/msconvert 
>>>> c:/Inetpub/wwwroot/ISB/data/dbase/OR20080317_S_SILAC-LH_1-1_01.RAW -v 
>>>> --mzXML -o c:/Inetpub/wwwroot/ISB/data/dbase --filter "peakPicking true 
>>>> [1,2]" *
>>>>
>>>> *Command FAILED*
>>>> RETURN CODE:13568
>>>>
>>>> Best,
>>>> Jesse
>>>>
>>>> On Thursday, July 23, 2015 at 2:01:02 PM UTC-7, Jesse wrote:
>>>>>
>>>>>  Hi David,
>>>>>
>>>>> I just sent you a link to the files with my new email address.  I 
>>>>> tried without the pI model and I got the same error.  I suspect a problem 
>>>>> with the network settings on the computers at work.  
>>>>>
>>>>> Thanks for looking into this for me.  
>>>>>
>>>>> Best,
>>>>> Jesse
>>>>>  ------------------------------
>>>>> *From:* [email protected] <javascript:> [
>>>>> [email protected] <javascript:>] on behalf of David 
>>>>> Shteynberg [[email protected] <javascript:>]
>>>>>
>>>>> *Sent:* Thursday, July 23, 2015 11:58 AM
>>>>> *To:* spctools-discuss
>>>>> *Subject:* Re: [spctools-discuss] Re: Processing MSGF+ searches
>>>>>
>>>>>   Hello Jesse, 
>>>>>
>>>>>  
>>>>>  I am not sure that I can pinpoint the error without access to your 
>>>>> file. Is this possible?  Otherwise you can try the analysis with the 
>>>>> following PeptideProphetParser options removing PI model which has not 
>>>>> been 
>>>>> extensively tested through MSGF+ and could be the culprit.
>>>>>
>>>>>  PeptideProphetParser 
>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.0 
>>>>> CLEVEL=2.5 
>>>>> PPM DECOYPROBS ACCMASS NONTT NONPARAM DECOY=XXX_ IGNORECHG=1
>>>>>  
>>>>>  If this works then the problem is with the pI model. 
>>>>>
>>>>>  Let me know if you can forward me your test.interact.pep.xml file to 
>>>>> test with.
>>>>>
>>>>>  Thank you,
>>>>> -David
>>>>>  
>>>>> On Wed, Jul 22, 2015 at 7:57 PM, Jesse <[email protected] <javascript:>> 
>>>>> wrote:
>>>>>
>>>>>> Hi David, 
>>>>>>
>>>>>>  I'm having problems recently running PeptideProphet on MSGF+ search 
>>>>>> output of GluC digests.  I tried the perl script you suggest but I'm not 
>>>>>> sure if it does anything because I'm not sure what it is supposed to do. 
>>>>>>  
>>>>>> That line is meant to replace a single "\" with "-", correct?  It seems 
>>>>>> to 
>>>>>> start OK but then it quits. The GUI then prints return code: 65280.  If 
>>>>>> you could make a quick suggestion as to whether you think the problem is 
>>>>>> my 
>>>>>> pep.xml files again or my install I would greatly appreciate it.  I 
>>>>>> tried 
>>>>>> both the development release and 4.8. 
>>>>>>
>>>>>>  C:/TPP/bin/xinteract (TPP v5.0.0a2 Development, Build xxxx-xxxx 
>>>>>> (x86_64))
>>>>>>  PPM mode in Accurate Mass Model ...
>>>>>>  PPM mode in Accurate Mass Model ...
>>>>>>
>>>>>> running: "C:/TPP/bin/InteractParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" 
>>>>>> "150624_0002_CR1_GluC_Xyl_0p4_rep1b.pep.XML" 
>>>>>> "150624_0003_CR1_GluC_Xyl_4_rep1.pep.XML" 
>>>>>> "150624_0004_CR1_GluC_Glc_0p4_rep1.pep.XML" 
>>>>>> "150624_0005_CR1_GluC_Glc_4_rep1.pep.XML" 
>>>>>> "150624_0007_CR1_GluC_Xyl_0p4_rep2.pep.XML" 
>>>>>> "150624_0008_CR1_GluC_Xyl_4_rep2.pep.XML" 
>>>>>> "150624_0009_CR1_GluC_Glc_0p4_rep2.pep.XML" 
>>>>>> "150624_0010_CR1_GluC_Glc_4_rep2.pep.XML" 
>>>>>> "150624_0012_CR1_GluC_Xyl_0p4_rep3.pep.XML" 
>>>>>> "150624_0014_CR1_GluC_Xyl_4_rep3.pep.XML" 
>>>>>> "150624_0015_CR1_GluC_Glc_0p4_rep3.pep.XML" 
>>>>>> "150624_0016_CR1_GluC_Glc_4_rep3.pep.XML" -L"7" -E"nonspecific""
>>>>>>  file 1: 150624_0002_CR1_GluC_Xyl_0p4_rep1b.pep.XMLWARNING: empty 
>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0002_CR1_GluC_Xyl_0p4_rep1b.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 2: 150624_0003_CR1_GluC_Xyl_4_rep1.pep.XMLWARNING: empty raw_data 
>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0003_CR1_GluC_Xyl_4_rep1.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 3: 150624_0004_CR1_GluC_Glc_0p4_rep1.pep.XMLWARNING: empty 
>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0004_CR1_GluC_Glc_0p4_rep1.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 4: 150624_0005_CR1_GluC_Glc_4_rep1.pep.XMLWARNING: empty raw_data 
>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0005_CR1_GluC_Glc_4_rep1.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 5: 150624_0007_CR1_GluC_Xyl_0p4_rep2.pep.XMLWARNING: empty 
>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0007_CR1_GluC_Xyl_0p4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 6: 150624_0008_CR1_GluC_Xyl_4_rep2.pep.XMLWARNING: empty raw_data 
>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0008_CR1_GluC_Xyl_4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 7: 150624_0009_CR1_GluC_Glc_0p4_rep2.pep.XMLWARNING: empty 
>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0009_CR1_GluC_Glc_0p4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 8: 150624_0010_CR1_GluC_Glc_4_rep2.pep.XMLWARNING: empty raw_data 
>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0010_CR1_GluC_Glc_4_rep2.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 9: 150624_0012_CR1_GluC_Xyl_0p4_rep3.pep.XMLWARNING: empty 
>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0012_CR1_GluC_Xyl_0p4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 10: 150624_0014_CR1_GluC_Xyl_4_rep3.pep.XMLWARNING: empty raw_data 
>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0014_CR1_GluC_Xyl_4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 11: 150624_0015_CR1_GluC_Glc_0p4_rep3.pep.XMLWARNING: empty 
>>>>>> raw_data in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0015_CR1_GluC_Glc_0p4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  file 12: 150624_0016_CR1_GluC_Glc_4_rep3.pep.XMLWARNING: empty raw_data 
>>>>>> in msms_run_summary tag ... trying mzML ...
>>>>>> Failed to open input file 
>>>>>> 'c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzML'.WARNING:
>>>>>>  cannot open data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzML
>>>>>>  in msms_run_summary tag ...... trying .mzXML ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>> SUCCESS: CORRECTED data file 
>>>>>> c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/150624_0016_CR1_GluC_Glc_4_rep3.mzXML
>>>>>>  in msms_run_summary tag ...
>>>>>>  processed altogether 186504 results
>>>>>> INFO: Results written to file: 
>>>>>> C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml
>>>>>> command completed in 86 sec 
>>>>>>
>>>>>> running: "C:/TPP/bin/DatabaseParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml""
>>>>>> command completed in 2 sec 
>>>>>>
>>>>>> running: "C:/TPP/bin/RefreshParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" 
>>>>>> "C:\Jesse\Ecoli.fasta""
>>>>>>   - Searching the tree...opening "c:/Jesse/Ecoli.fasta" as 
>>>>>> "c:/Inetpub/wwwroot/ISB/data/2015/Kac_GluC/Ecoli.fasta"
>>>>>>
>>>>>>   - Linking duplicate entries...  - Printing results...
>>>>>>
>>>>>>   - Building Commentz-Walter keyword tree...command completed in 22 sec 
>>>>>>
>>>>>> running: "C:/TPP/bin/PeptideProphetParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.05 
>>>>>> CLEVEL=2.5 PPM PPM ACCMASS PI NONTT NONPARAM DECOY=XXX_ IGNORECHG=1"
>>>>>> using Accurate Mass Bins
>>>>>> using PPM mass difference
>>>>>> using pI
>>>>>> Using Decoy Label "XXX_".
>>>>>> Ignoring charge 1+ spectra.
>>>>>> Not using ntt model
>>>>>> Using non-parametric distributions
>>>>>>  (MS-GF+)WARNING: Support of MSGF+ may not be full.  There exist known 
>>>>>> issues with the way MSGF+ encodes certain modifications in pep.xml that 
>>>>>> may not be correct. Also, high-scoring DECOY have been observed in MSGF+ 
>>>>>> analysis.  The user is encouraged to be vigilant in comparing model 
>>>>>> estimated error-rates to the DECOY-estimated error-rates to make sure 
>>>>>> the two agree and set CLEVEL parameter accordingly: see 
>>>>>> http://tools.proteomecenter.org/wiki/index.php?title=TPP:Frequently_Asked_Questions#What_is_CLEVEL_and_when_do_I_use_it.3F
>>>>>> adding Accurate Mass mixture distr
>>>>>> adding pI mixture distr
>>>>>> init with MS-GF+ nonspecific 
>>>>>>
>>>>>> command "C:/TPP/bin/PeptideProphetParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.05 
>>>>>> CLEVEL=2.5 PPM PPM ACCMASS PI NONTT NONPARAM DECOY=XXX_ IGNORECHG=1" 
>>>>>> failed: Unknown error
>>>>>>
>>>>>> command "C:/TPP/bin/PeptideProphetParser 
>>>>>> "C:/tmp/a03524/2015/Kac_GluC/test.interact.pep.xml" MINPROB=0.05 
>>>>>> CLEVEL=2.5 PPM PPM ACCMASS PI NONTT NONPARAM DECOY=XXX_ IGNORECHG=1" 
>>>>>> exited with non-zero exit code: 255
>>>>>> QUIT - the job is incomplete
>>>>>>
>>>>>>  
>>>>>> On Thursday, July 9, 2015 at 2:33:16 PM UTC-7, [email protected] 
>>>>>> wrote: 
>>>>>>>
>>>>>>> Hi David,
>>>>>>>
>>>>>>> I can cope with the command line. Thanks for the info I never would 
>>>>>>> have worked that one out...
>>>>>>>
>>>>>>> Peter
>>>>>>>
>>>>>>> On Thursday, July 9, 2015 at 2:55:41 PM UTC+10, [email protected] 
>>>>>>> wrote: 
>>>>>>>>
>>>>>>>>  Hi,
>>>>>>>>
>>>>>>>>
>>>>>>>> I want to use the TPP to combine, Mascot, X!Tandem and MSGF+ 
>>>>>>>> searches (amongst other things). I'm having trouble getting around 
>>>>>>>> some of 
>>>>>>>> the basics. I have successfully used the TPP in the past to process 
>>>>>>>> samples, but only with Mascot data.
>>>>>>>>
>>>>>>>>  Once I get my MSGF+ output files converted to pepXML I should be 
>>>>>>>> fine. I cannot work out how I get the MSGF+ files converted. The 
>>>>>>>> output 
>>>>>>>> generated by MSGF+ is an mzid file. I am also unclear as to where the 
>>>>>>>> database (with decoys) and mzXML files, used for searching, need to be 
>>>>>>>> located when generating this pepXML file. I have noticed error 
>>>>>>>> messages in 
>>>>>>>> the logs about accessing the database and mzXML file. I am generally 
>>>>>>>> using 
>>>>>>>> the Petunia interface as it's much nicer to work with multiple files.
>>>>>>>>
>>>>>>>>
>>>>>>>>  Thanks,
>>>>>>>>
>>>>>>>>
>>>>>>>>  Peter
>>>>>>>>  
>>>>>>>     -- 
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>>>>>  
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>>
>>
>>
>> -- 
>> Joe Slagel
>> Institute for Systems Biology
>> [email protected] <javascript:>
>>
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>
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