Hi Adam,

We have plans to add some of these features to Libra as well as others, but
none are ready at the moment.

One thing you could try is to select to normalize against the sum of the
reagent profiles (instead of selecting a channel to quantify against) --
this should give you a value for all channels, even when some are missing.

Cheers,
--Luis


On Fri, Nov 10, 2017 at 11:44 AM, Adam R <[email protected]> wrote:

> Is there a way to retain quantified peptides for the protein quant with
> Libra? I understand that Libra discards peptides without all
> channels...what about in instances where the you expect there to be little
> or no intensity? I have data from pulldowns where we don't expect to see
> much of the protein in the presence of a competitive inhibitor, so in this
> case it would be of use to retain such quants where the intensity is zero
> in the presence of inhibitor but several thousands in the pulldown
> channel...Is there a way to toggle on/off the peptides that are used for
> the protein quant in Libra? I'm thinking along the lines like in Xpress
> where you can toggle whether or not a peptide is used for the protein
> quant. Is there also a way to modify the number of standard deviations that
> are used to discard a peptide from being used in the protein quant?
>
> Best,
>
> Adam
>
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