Hello Vidya,

Unfortunately, I don't have that release easily available.  You will have
to build the tools on your system.

Thanks,
-David

On Thu, Jul 12, 2018 at 10:14 PM, Vidya Venkatraman <[email protected]
> wrote:

> I am using CentOS release 6.3
>
> Regards
> Vidya
>
> On Tue, Jul 10, 2018 at 4:57 PM, David Shteynberg <David.Shteynberg@
> systemsbiology.org> wrote:
>
>> Which version of linux are you using?  I may be able to provide a binary
>> for you.  Or you can recompile from source.
>>
>> Cheers,
>>
>> -David
>>
>> On Tue, Jul 10, 2018 at 4:50 PM, Vidya Venkatraman <
>> [email protected]> wrote:
>>
>>> I am using Linux. Do i need to compile it again?
>>>
>>> Regards
>>>
>>> On Tue, Jul 10, 2018 at 12:07 PM, David Shteynberg <
>>> [email protected]> wrote:
>>>
>>>> Hello Vidya,
>>>>
>>>> I have added the support of Morpheus into the TPP codebase.  Please let
>>>> me know which OS (windows or linux) you are processing on so I can provide
>>>> you with an executable that you should be able to use.
>>>>
>>>> Thanks,
>>>> -David
>>>>
>>>> On Mon, Jun 25, 2018 at 1:09 PM, Vidya Venkatraman <
>>>> [email protected]> wrote:
>>>>
>>>>> I just shared a box folder with you which contains mzML, fasta and the
>>>>> pepxml file.
>>>>>
>>>>> https://cedars.app.box.com/folder/50657299852
>>>>>
>>>>> Regards
>>>>> Vidya
>>>>>
>>>>> On Mon, Jun 25, 2018 at 9:41 AM, David Shteynberg <
>>>>> [email protected]> wrote:
>>>>>
>>>>>> Hello Vidya,
>>>>>>
>>>>>> Currently, there is no support for Morpheus in the TPP.  If you are
>>>>>> able to place you search results in a shared drive and send me a link for
>>>>>> testing, I should be able to add the Morpheus support back in.
>>>>>>
>>>>>> Thanks,
>>>>>> -Davod
>>>>>>
>>>>>> On Sat, Jun 23, 2018 at 3:25 PM, Vidya Venkatraman <
>>>>>> [email protected]> wrote:
>>>>>>
>>>>>>> Hi David,
>>>>>>>
>>>>>>> I am using TPP v5.1.0 and when i try to run xinteract on the
>>>>>>> Morpheus pep.xml, I get the following error that engine Morpheus not
>>>>>>> recognized. Any ideas if I am missing something?
>>>>>>>
>>>>>>> xinteract (TPP v5.1.0 Syzygy, Build 201806211802-exported
>>>>>>> (Linux-x86_64))
>>>>>>>
>>>>>>> running: "/hpc/apps/TPP/5.1.0/bin/InteractParser
>>>>>>> 'interact.morpheus.pep.xml' '2017-12-4_ABRF_200_DDA1.pep.xml' -L'7'"
>>>>>>>  file 1: 2017-12-4_ABRF_200_DDA1.pep.xml
>>>>>>>  processed altogether 72135 results
>>>>>>> command completed in 9 sec
>>>>>>>
>>>>>>> running: "/hpc/apps/TPP/5.1.0/bin/DatabaseParser
>>>>>>> 'interact.morpheus.pep.xml'"
>>>>>>> command completed in 1 sec
>>>>>>>
>>>>>>> running: "/hpc/apps/TPP/5.1.0/bin/RefreshParser
>>>>>>> 'interact.morpheus.pep.xml' '/common/venkatramanv/Data/Pra
>>>>>>> tik/Thermo/DDA/raw/PRG2016_DECOY.fasta'"
>>>>>>>
>>>>>>>   - Searching the tree...
>>>>>>>   - Linking duplicate entries...
>>>>>>>   - Printing results...
>>>>>>>
>>>>>>> command completed in 15 sec
>>>>>>>
>>>>>>> running: "/hpc/apps/TPP/5.1.0/bin/PeptideProphetParser
>>>>>>> 'interact.morpheus.pep.xml' ACCMASS RT NONPARAM DECOYPROBS DECOY=DECOY_"
>>>>>>> using Accurate Mass Bins
>>>>>>> using RT
>>>>>>> Using Decoy Label "DECOY_".
>>>>>>> Decoy Probabilities will be reported.
>>>>>>> Using non-parametric distributions
>>>>>>>  (Morpheus)
>>>>>>> error: engine Morpheus not recognized
>>>>>>>
>>>>>>> command "/hpc/apps/TPP/5.1.0/bin/PeptideProphetParser
>>>>>>> 'interact.morpheus.pep.xml' ACCMASS RT NONPARAM DECOYPROBS DECOY=DECOY_"
>>>>>>> exited with non-zero exit code: 256
>>>>>>> QUIT - the job is incomplete
>>>>>>>
>>>>>>> Thanks
>>>>>>> Vidya
>>>>>>>
>>>>>>> On Friday, February 7, 2014 at 12:22:54 PM UTC-8, David Shteynberg
>>>>>>> wrote:
>>>>>>>>
>>>>>>>> I was able to make a first stab attempt at it and I was successful
>>>>>>>> after minor modification to the way spectrum_names are encoded in
>>>>>>>> spectrum_query tags in the morpheus pepXML files.  After running a 
>>>>>>>> simple
>>>>>>>> sed to replace the names with something that wouldn't overlap with 
>>>>>>>> anoth
>>>>>>>> file when combined by using the each run's basename I was able to 
>>>>>>>> generate
>>>>>>>> results.
>>>>>>>>
>>>>>>>>
>>>>>>>> My PeptideProphet processed analysis for these two searches can be
>>>>>>>> downloaded here:
>>>>>>>>
>>>>>>>> https://www.dropbox.com/s/f5r8j5yj2p2r3b8/morpheus_interact.tgz
>>>>>>>>
>>>>>>>>
>>>>>>>> Here are my sed commands, but I hope this could be fixed within
>>>>>>>> morpheus.
>>>>>>>>
>>>>>>>>  sed -i 's/controllerType=0 controllerNumber=1
>>>>>>>> scan=[0-9]*/OR20080317_S_SILAC-LH_1-1_01/g'
>>>>>>>> OR20080317_S_SILAC-LH_1-1_01.pep.xml
>>>>>>>>
>>>>>>>>
>>>>>>>>  sed -i 's/controllerType=0 controllerNumber=1
>>>>>>>> scan=[0-9]*/OR20080320_S_SILAC-LH_1-1_11/g'
>>>>>>>> OR20080320_S_SILAC-LH_1-1_11.pep.xml
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>> Cheers,
>>>>>>>> -David
>>>>>>>>
>>>>>>>>
>>>>>>>> P.S.  I expect to merge this into the SVN codebase sooner than
>>>>>>>> later.
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>>
>>>>>>>> On Fri, Feb 7, 2014 at 8:35 AM, Dave Trudgian <
>>>>>>>> [email protected]> wrote:
>>>>>>>>
>>>>>>>>> David,
>>>>>>>>>
>>>>>>>>> That's the same data. I've made PepXML and the other Morpheus
>>>>>>>>> output available at:
>>>>>>>>>
>>>>>>>>> https://proteomics.swmed.edu/data/morpheus_tpp/
>>>>>>>>>
>>>>>>>>> DT
>>>>>>>>>
>>>>>>>>>
>>>>>>>>> On Thursday, February 6, 2014 5:36:35 PM UTC-6, David Shteynberg
>>>>>>>>> wrote:
>>>>>>>>>
>>>>>>>>>> I was referring to this data:
>>>>>>>>>>
>>>>>>>>>> http://tools.proteomecenter.org/wiki/index.php?title=TPP_Tut
>>>>>>>>>> orial_v2
>>>>>>>>>>
>>>>>>>>>> However, this is not high res MS/MS either.  This would be a good
>>>>>>>>>> starting point.  The decoys and targets don't have to separate by 
>>>>>>>>>> score
>>>>>>>>>> alone, PeptideProphet should be able to model the plots you show in 
>>>>>>>>>> either
>>>>>>>>>> case.
>>>>>>>>>>
>>>>>>>>>> Cheers,
>>>>>>>>>> -David
>>>>>>>>>>
>>>>>>>>>>
>>>>>>>>>> On Thu, Feb 6, 2014 at 3:13 PM, Dave Trudgian <david.t...@
>>>>>>>>>> utsouthwestern.edu> wrote:
>>>>>>>>>>
>>>>>>>>>>> Hi David,
>>>>>>>>>>>
>>>>>>>>>>> Am happy to generate some pepXMLs from the tutorial data, but
>>>>>>>>>>> assuming you mean the stuff at:
>>>>>>>>>>>
>>>>>>>>>>> ftp://ftp.peptideatlas.org/pub/PeptideAtlas/Repository/TPP_D
>>>>>>>>>>> emo2009/
>>>>>>>>>>>
>>>>>>>>>>> ... I'm not sure that's the best to work with for Morpheus. It's
>>>>>>>>>>> CID Ion-trap MS/MS, which is not Morpheus' target. Morpheus doesn't 
>>>>>>>>>>> work as
>>>>>>>>>>> well as other algorithms on low-res MS/MS so I'm not sure if anyone 
>>>>>>>>>>> would
>>>>>>>>>>> want to use it like that.
>>>>>>>>>>>
>>>>>>>>>>> I grabbed two of the result sets from the Coon lab site - Yeast
>>>>>>>>>>> analysis with FT HCD or IT CID. The distributions of Morpheus 
>>>>>>>>>>> scores are
>>>>>>>>>>> very different. The CID data doesn't even look like target and decoy
>>>>>>>>>>> matches are separable, so I think high-res MS/MS is a must. See 
>>>>>>>>>>> attached.
>>>>>>>>>>>
>>>>>>>>>>> DT
>>>>>>>>>>>
>>>>>>>>>>>
>>>>>>>>>>> On Thursday, February 6, 2014 3:44:08 PM UTC-6, David Shteynberg
>>>>>>>>>>> wrote:
>>>>>>>>>>>
>>>>>>>>>>>> I was dabbling in this, but running into some issues with
>>>>>>>>>>>> morpheus slowing my machine to a point where I was unable to do 
>>>>>>>>>>>> any other
>>>>>>>>>>>> work so I moved to another project.  However, I am certainly still
>>>>>>>>>>>> interested in this, but I know that pepXML coming out of morpheus 
>>>>>>>>>>>> may need
>>>>>>>>>>>> some work.  If you'd be willing to generate some pepXML's from the 
>>>>>>>>>>>> tutorial
>>>>>>>>>>>> data and work with me to correct the pepXML issues I should be 
>>>>>>>>>>>> able to
>>>>>>>>>>>> model the results quite quickly with PeptideProphet.  Please let 
>>>>>>>>>>>> me know if
>>>>>>>>>>>> that sounds good to you.
>>>>>>>>>>>>
>>>>>>>>>>>> Cheers,
>>>>>>>>>>>> -David
>>>>>>>>>>>>
>>>>>>>>>>>>
>>>>>>>>>>>> On Thu, Feb 6, 2014 at 12:08 PM, Eric Deutsch <
>>>>>>>>>>>> [email protected]> wrote:
>>>>>>>>>>>>
>>>>>>>>>>>>> Hi Dave, at ISB we are not planning this, so please go ahead
>>>>>>>>>>>>> and let us know how it goes!
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>> Regards,
>>>>>>>>>>>>>
>>>>>>>>>>>>> Eric
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>> *From:* [email protected] [mailto:spctools...@
>>>>>>>>>>>>> googlegroups.com] *On Behalf Of *Dave Trudgian
>>>>>>>>>>>>>
>>>>>>>>>>>>> *Sent:* Thursday, February 06, 2014 12:02 PM
>>>>>>>>>>>>> *To:* [email protected]
>>>>>>>>>>>>>
>>>>>>>>>>>>> *Subject:* [spctools-discuss] Re: support for Morpheus search
>>>>>>>>>>>>> algorithm in TPP
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>> Craig, just wondering if you or anyone else is working on
>>>>>>>>>>>>> this? If not I was thinking I would have a go at putting in a 
>>>>>>>>>>>>> Morpheus
>>>>>>>>>>>>> model for PeptideProphet towards the end of next week.
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>> Dave Trudgian
>>>>>>>>>>>>>
>>>>>>>>>>>>> On Saturday, November 30, 2013 4:37:30 PM UTC-6, Craig Wenger
>>>>>>>>>>>>> wrote:
>>>>>>>>>>>>>
>>>>>>>>>>>>> Is there a mechanism for adding support for a new search
>>>>>>>>>>>>> algorithm to the various TPP tools? A few users have requested TPP
>>>>>>>>>>>>> compatibility for the Morpheus
>>>>>>>>>>>>> <http://morpheus-ms.sourceforge.net/> search algorithm. It
>>>>>>>>>>>>> already outputs pepXML.
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>> -Craig
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>>
>>>>>>>>>>>>> --
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