Hi David,
You can find the mzML, Comet parameters and FASTA file 
here:https://www.dropbox.com/t/Yld0ZBWhsuFajeLj
The link is valid for 7 days.
Many thanks,
Oded

On Monday, 12 April 2021 at 23:46:08 UTC+3 David Shteynberg wrote:

> I don't mind taking a crack at it over vacation.   Please let me know 
> where I can pull the data from. I might not have quick solution for you but 
> I can get started looking for the problem.  Which search engine did you use 
> here?   I would need mzML data search results and the fasta database to get 
> started. 
>
> Thanks!
>
>
>
> Thanks!
>
> On Mon, Apr 12, 2021, 1:38 PM Oded <[email protected]> wrote:
>
>> Hi David,
>> Thank you for the quick reply. We are using TPP v6.0.0-rc14 Noctilucent, 
>> Build 202103031119-8400 (Windows_NT-x86_64).
>> As for the data let me know when you are back and I will transfer you 
>> either the raw file or the search results.
>> Enjoy your vacation.
>> Thanks,
>> Oded
>> On Monday, 12 April 2021 at 22:17:53 UTC+3 David Shteynberg wrote:
>>
>>> Hi Oded,  Which release candidate are you referring to?  The earlier 
>>> candidates may have a bug that is corrected in a later version. If you can 
>>> share some data and specifics about the missing PSMs I can run it here and 
>>> troubleshoot the problem.   
>>>
>>> Thanks!
>>>
>>> David 
>>>
>>> P.S. I am on vacation this week so will troubleshoot next week.
>>>
>>> On Mon, Apr 12, 2021, 11:49 AM Oded <[email protected]> wrote:
>>>
>>>> Hi there,
>>>> We recently download the TPP 6.0 RC and while using it we noticed that 
>>>> we obtain fewer peptides IDs than what we got for the same dataset and 
>>>> search output with version 5.2.
>>>> Many of the missing peptides seem to have decent Expect value and MS/MS 
>>>> following a visual inspection. 
>>>> This seems that this is due to changes in PeptideProphet and are not 
>>>> related to the search itself that was done with Comet.
>>>> Is there any additional parameter that should be included in the new 
>>>> version in order to restore the missing peptides?
>>>> Many thanks,
>>>> Oded
>>>>
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