Actually Bob, I find the standard method of examination, acceptance and "licensure" as conducted by the medical, chemical, scientific, industrial and regulatory communities in general to be perfectly flawed for two reasons. The first is precisely due to the premise that you suggest, that "the onus be on evidence of harm."


As soon as I sent the preceding statement I should not have. I agree with you that when dealing with the unknown, that the burden of proof should be to prove safety. That having been said, the context from which I am talking is simply that I understand the chemistry and metabolism of the material and from my perspective they raise no flags. Also, the product has been in use by large numbers of folks for some time with little evidence of risk. Common sense tells me I am not going to sweat it. Life is full of risks and I don't see this as a big one.



Is it neccessary to point to the literally thousands of instances where "evidence of harm" has been discovered long after "absence of evidence" was sufficient cause for peer/regulatory acceptance and public release of a material, chemical or drug? Or would you care for me to point out the literally thousands of instances of effort to discredit, downplay or hide incidents and/or revelations of harm well after peer and regulatory acceptance and public release? Or should you be directed to the literally thousands of instances where evidence of harm has been manipulated to the appearance of being diminutive, or "statistically insignificant" or withheld altogether from peer, regulatory and public review?


Ok, lets say I agree to your standard of absolute proof of safety before proceeding with anything "new" When do we assume that a particular activity or exposure posesses a low enough risk to get on with our lives?


No Bob, when delving into the world of the dieties, the onus should be on proof of absence, not absence of proof. "Proof" all too often takes far more than a two year clincial study on adulterated lab mice - frequently years, a generation or more to become self-evident. This, of course, you well know.

The second flaw is universal embrace of "acceptable risk" (at the regulatory, industrial and scientific levels) and the institution/application of both the acceptance and the risk in the public sector where there is no need for either to be present. Aspartame, no different than saccharine, became the "cure all" pill for a complacent society that increasingly has given up on lifestyles that include moderate amounts of exercise ("hard work" is not a substitute for physical exertion) and dietary discipline. As a result of the economic exploitation to be derived from that cash cow, half or more of a global society has now been and is continually being exposed to a chemical that is virtually needless and has been proven to be useless as a curative, in light of the fact that per capita caloric consumption has risen, not declined, in western societies since the infusion of aspartame into the marketplace.


you are preaching to choir again, Todd. I agree that it has little or value. I am trying to address relative risk.

There are actually two other flaws in the logic both you and John Hayes would apparently care to apply, or perhaps not apply. The first is that not every person's physiology is duplicit, which in turn demands that not everyone is going to react duplicitly to the same set of inputs, much less varying sets of inputs - erego the "practice" of medicine. Oddly enough, professionals ranging from engineers, to doctors, to lawyers to science in general attempt to leverage opinion and acceptance using their supposed vast arrays of knowledge in comparison to those who have not been inundated under similar regimens. Yet on the other hand, these same professionals and institututions of such superior training are the first to fall back on the excuses that can be derived from the unknown.

I am well aware of idosyncratic reactions.


All rather queer how in one venue/conversation their opinions are to be accepted as absolute, yet in the very next breath the expectation is that they be given full lattitude for error based upon what isn't known.

thats life, its imperfect.

Relative to the gene that converts phenylalanine to tyrosine, there are over 100 mutations.

actually it is an enzyme , not a gene.
The corresponding conversion rate is zero to normal. For science, medical, regulatory and industry "professionals" to declare aspartame as being "safe," when it has the incumbent ability to affect in a less than positive manner to some degree or another a broad spectrum of the body public - not just specifically one sector deficient of a precise amount of ability/inability to process phenylalanine - is irresponsible, perhaps even criminal.

Gee, that is a pretty broad indictment. The problem is that this argument is applicable to any substance passing thru the body. How do we ever determine what is safe?

Even more substantial in this disease of irresponsibilty is the fact that dosage of phenylalanine (aspartame) is unregulated. It is an accepted fact (at least amongst those who care to walk through life with their eyes open) that hundreds of millions of consumers slam untold quantitiies of aspartame (phenylalanine) daily via "dietetic" soft drinks and food stuffs. In a world filled with moderate dis-ability to process phenylalanine suffciently, this can only result in a compound fracture of unknown proportions - certainly not proportional to any two year clincal study on lab mice.

Furthermore, to demand that test results be yielded to support any premise of affects beyond those suffering within the specific range of Phenylketonuria (PKU), with the full knowledge that by and large the expense of such testing falls well outside the finacial abilities of all but the very institutions that hold stake in them not being conducted, is at best an expression of inhibition to serve the greater interests of the public. Whether that inhibition is derived from lack of motivation to think more fully for one's self rather than following the indoctrinational course of established institutions or as a result of self-interests is not particularly a matter for me to decide here and now.

What is inevitable and infinitely amazing is the fact that if and/or when such sudies are conducted or existing data is sufficiently amassed and corrolaries drawn, this same body of supposedly learned professionals and their incumbent groupies will spend inordinate amounts of time and money attempting to insert their supposition of "fact" (inclusive of all the unknowns and "statistical insignificance" embodied within their "facts"), into every crevice of substantiality in order to relegate any premise to the point of obscurity, or as John Hayes would care to put it, "psuedo-science."

No Bob. What I find is that people who selectively design their parameters of acceptance to omit those obvieties that least suit their convenience, preference, purpose or intent are those who are living largely in a less than honest world. Those who acknowledge what isn't known are the ones who living in a spectrum of reality and more prone to both be believed and seen as serving the public good.

Reason, as well as reality, all too often defies convention, much less what you may care to call "conventional wisdom."

Finally, there is that small matter of "safe." Unfortunately, application of the term by the body public is slightly askew from how it is applied by the scientific, regulatory and industrial communities. To the average citizen, "safe" implies without risk, harm or similar dis-benefit. It is interpreted as static and absolute. On the other hand, "safe" has a relative meaning in the "professional" world. The sad truth of the matter is the manner in which the professional, regulatory and industrial sectors exploit this difference in interpretation in order to sell a product and/or belief to the consuming public, with full knowledge that a general desception is being effected.

Pick a field or subject and take notice of how often these truths are applicable and how frequently the public is mis-lead to its detriment.


I guess we will just have to agree to disagree

toodles



Todd Swearingen

----- Original Message ----- From: "bob allen" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Friday, October 29, 2004 8:53 AM
Subject: Re: [Biofuel] C.Difficile Epidemic in Quebec


Appal Energy wrote:

Bob,

I'm at a bit of a loss with this one. Don't suppose you would care to qualify your opinion with something more than "quack, quack" would you? As I recall the last time I visited the aspartame issue (researched it for several weeks, up one side and down the other) the problems and concerns were very real. Aspartame hasn't changed. Human biology hasn't changed.


Neither human biology nor the scientific standards of proof. Let me say first that I don't use aspertame, don't promote its use, or even think it has value in our society, oh and I don't hold any stock in or have any connection with the product. That having been said, the facts are simple . there is no scientific evidence which shows harm in the normal use of this product, with the single exception of infants diagnosed with PKU. Asking me to prove it does no harm is well nigh impossible. (the old proving a negative problem)

Todd, you said you investigated the issue. What are your findings. Shouldn't the onus be on evidence of harm? What did you find, beyond testimonials and feeble speculation? Animal studies, well controlled laboratory results, Double blind trials? Where is the evidence? And I don't mean things like "aspertame contains methanol, methanol is poisonous, therefore Aspertame is poisonous". Or "the body is not used to amino acids". I have seen these arguments way too many times. Give me studies in per reviewed journals, and I will give a look see and let you know of my conclusions.


We both know that just because something has found its way onto the shelf and been assigned a status of "below regulatory concern" by a very biased institutional process that doesn't somehow make reality disappear.

Something a little more "concrete" from someone other than Donald Rumsfeld would serve well at the moment.


Ok how about this, Some 50 plus million people here in US use it daily, why hasn't epidemiological evidence turned up harm? I was a graduate student many years back. I mention this only to point out that proving that conventional wisdom is wrong is sort of a holy grail to science researchers across the universe. If there is data to disprove the conventional wisdom that aspertame is safe as used, then why hasn't a graduate student in epidemiology found anything?


Todd Swearingen


----- Original Message ----- From: "bob allen" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Thursday, October 28, 2004 10:08 AM
Subject: Re: [Biofuel] C.Difficile Epidemic in Quebec


Nothing personal to you but all I can say about Mercola is QUACK, QUACK. see for example his totally bogus, nonscientific diatribe about aspertame. It is right up there with other wackos such as Betty Martini.
http://bmj.bmjjournals.com/cgi/eletters/329/7469/755#76712


Legal Eagle wrote:

Thanks for the links. Dr Marcola is a known specialist in his field, so this should prove an interesting read.
Luc
----- Original Message ----- From: "Dan Volker" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Wednesday, October 27, 2004 10:18 AM
Subject: RE: [Biofuel] C.Difficile Epidemic in Quebec


Probiotics are something I researched heavily about 6 months ago, when I began using what I have found to be by far the best available. Here is one link which explains the product well in summary form, and there are many
sites which explain the homeostatic soil organism concept at extreme
detail..The probiotic I am referring to is called Primal Defense, made by
"Garden of Life"...visit http://www.risingstarlc.com/pdindex.htm


Also, regarding flu epidemics, shortages of vaccines, and the foolishness of
using vaccines period, visit
http://www.mercola.com/2004/oct/20/flu_vaccine.htm

Regards,
Dan Volker

-----Original Message-----
From: [EMAIL PROTECTED]
[mailto:[EMAIL PROTECTED] On Behalf Of Legal Eagle
Sent: Wednesday, October 27, 2004 10:13 AM
To: [EMAIL PROTECTED]
Subject: Re: [Biofuel] C.Difficile Epidemic in Quebec

Muchas Gracias Kim;

After having a peruse I may even want to give it a link in
the Oragnics Section of my site or something. We all need to
seek out ways to better our health. No one is going to avoid
dying, but we sure can have a good and long quality of life though.
Luc
PS:Maybe I should be thinking of adding a section only for
probiotics. I already have an article on it, but sources I do
not have.Hmmm, worth a thought.
----- Original Message -----
From: "Kim & Garth Travis" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Wednesday, October 27, 2004 9:08 AM
Subject: Re: [Biofuel] C.Difficile Epidemic in Quebec


> Wonderful advice Luc.  I would add that kefir taken daily really
> promotes good health. Kefir grains really are Mother Nature's best
> defence for health.  The nice part, is that one aquires
grains just by
> paying the shipping, then in a couple of weeks, you have lots of
> grains to share with family and friends.  Learn more at:
> http://users.chariot.net.au/~dna/kefirpage.html
>
> Bright Blessings,
> Kim
>
> At 07:52 AM 10/27/2004, you wrote:
>>http://www.cbc.ca/story/science/national/2004/10/26/cdiffici
le_queplan
>>041026.html
>>
>>Check out what they are doing to curb it. Reducing
anti-biotics, duh.
>>Anti-biotics overuse has resulted in many more diseases
than they have
>>"cured". All the while attacking "bad" bacteria they also
eliminate "good"
>>bacteria leaving the immune system depleted of it's
defenses and then
>>along comes Mr. Pathogen (just like in tress) and wreaks a
nightmare,
>>and because these pathogen are so prolific it isn't long
before what
>>was a minor problem becomes a major health concern, just
like over use
>>of fertilizers in soil. Same causation, same effect.
>>When T cells are healthy the immuno functions, including the lymph,
>>cleans out and purify the blood and move dead cells and other
>>pathogens along to be disposed of, but if the immuno functions are
>>weakened by anti-biotic overkill then the lymph can't do
it's job properly and you get  ... sick.
>>When anti-biotics MUST be used it is recommended that a
probiotic such
>>as acidophilus accompany it to offset some of the negative
effects of
>>the immuno depletion Of course there are exemptions, as in
all rules,
>>but this is the standard, now starting to be admitted by the
>>"community" of those heralding themselves as "health
experts". HRT was
>>a really good earner, I mean solution, until they were
forced to admit
>>it is a carcinogen. Vioxx was a really good earner, oops, I mean
>>solution until people started killing themselves. Lipitor
wa a really
>>good... unti it also proveed to be counter-health producting.
>>Moral of the story ? Live a healthy life and feed your body
with high
>>quality healthy fresh foods and you won't have to worry
about finding
>>a "solution" later.
>>
>>Luc
>
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