Oh - if I Use the hsa:7097 as an input (Now I see it mentioned in your
email! It was not set on the workflow port description or example) -
then I do get lots of results and every box turns grey.. at least when
I have turned off provenance from Preferences.

These don't give any output, though:

go_term_accession
go_term
go_term_definition
publication_title
publication_abstract
publication_pubmed_id
publication_author
publication_journal_name


There is a bug in that if an empty list is returned, nothing is shown
(T2-618) - worth checking if this is the case for these ports.



Stuart says the workflow file indicates it's been made with an earlier
nightly snapshot or beta 1 - Eddie, has there been any recent Moby
changes that could affect this workflow? Is it worth trying to build
it from scratch in beta 2? (looks like a big job!)

When I connect up an output port from Gene2PubMed_Publication (before
the parser that makes publication_.*) I do get lots of items like:

<moby:MOBY xmlns:moby="http://www.biomoby.org/moby";>
  <moby:mobyContent>
    <moby:mobyData moby:queryID="a28">
      <moby:Simple moby:articleName="publications">
        <moby:Publication moby:id="11724772" moby:namespace="PMID">
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Seiji Murakami</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Daisuke Iwaki</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Hiroaki Mitsuzawa</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Hitomi Sano</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Hiroki Takahashi</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Dennis R Voelker</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Toyoaki Akino</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Author">Yoshio Kuroki</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Year">2002</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Abstract">Pulmonary surfactant protein A (SP-A)
plays an important role in modulation of the innate immune system of
the lung. Peptidoglycan (PGN), a cell wall component of Gram-positive
bacteria, is known to elicit excessive proinflammatory cytokine
production from immune cells. In this study we investigated whether
SP-A interacts with PGN and alters PGN-elicited cellular responses.
Binding studies demonstrate that PGN is not a ligand for SP-A.
However, SP-A significantly reduced PGN-elicited tumor necrosis factor
alpha (TNF-alpha) secretion by U937 cells and rat alveolar
macrophages. The inhibitory effect on TNF-alpha secretion was
dependent upon SP-A concentrations in physiological range.
Coincubation of SP-A and PGN with human embryonic kidney 293 cells
that had been transiently transfected with the cDNA of Toll-like
receptor 2 (TLR2), a cell signaling receptor for PGN, significantly
attenuated PGN-induced nuclear factor-kappaB activity. SP-A directly
bound to a soluble form of the recombinant extracellular TLR2 domain
(sTLR2). Coincubation of sTLR2 with SP-A significantly reduced the
binding of sTLR2 to PGN. These results indicate that the direct
interaction of SP-A with TLR2 alters PGN-induced cell signaling. We
propose that SP-A modulates inflammatory responses against the
bacterial components by interactions with pattern-recognition
receptors.</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Title">Surfactant protein A inhibits
peptidoglycan-induced tumor necrosis factor-alpha secretion in U937
cells and alveolar macrophages by direct interaction with toll-like
receptor 2.</moby:String>
          <moby:String moby:id="" moby:namespace=""
moby:articleName="Journal">The Journal of biological
chemistry</moby:String>
        </moby:Publication>
      </moby:Simple>
    </moby:mobyData>
  </moby:mobyContent>
</moby:MOBY>


So it seems there might be a problem in the Moby parser.


On Thu, Jul 9, 2009 at 10:10, Stian
Soiland-Reyes<[email protected]> wrote:
> On Wed, Jul 8, 2009 at 18:25, Mark Wilkinson<[email protected]> wrote:
>
>> Another oddity just popped-up.  Probably best if you run this workflow
>> yourselves to see the problem (attached) - use input "hsa:7097" as the value
>> for the input "id" slot.
>>
>> About half of the output bins contain no data, though the output of the node
>> that feeds into that bin is clearly full and happy...  I can't see any
>> obvious difference between the bins that contain data and the bins that
>> don't...
>
> I had a similar problem the other day - some of the output ports
> didn't show the result values - but when I clicked for the
> intermediate results of the processor feeding to that port, there's
> output there. Also if I add a dummy processor in the middle (Echo
> list) before the workflow output port, then I do get to see the value.
>
> In the workflow I used the outputs came from an XML splitter, so all
> the values should have come..
>
> The workflow I used was using a caGrid plugin, so there's not much
> point in sharing it here, but I can try to find a similar one.
>
>
> Could it possibly have something to do with the 'Workflow finished'
> sign? Do the output bins (good name, Mark!) stop receiving the outputs
> at some point?
>
>
>
> I can replicate the empty bins, but I have no idea what KEGG ID to use
> as no example was provided, I tried using "path:hsa05216". What I find
> is that most of the processors don't seem to have run (they are not
> greyed out) - but it still says 'Workflow complete'.
>
> Could there be something with error handling within the BioMoby
> activity that is not working as expected?
>
> (Note developers - as this is a Moby workflow it's affected by T2-602
> and intermediate values don't work)
>
> It seems everything from ConvertSnp2EntrezGeneID and below don't run -
> but I don't get any warnings or errors on the console, even though
> I've turned up logging.
>
> We would need to run this one through a debugger to see what is really
> going on.. I'll see if anyone here has time to do that.
>
> I've created a bug: http://www.mygrid.org.uk/dev/issues/browse/T2-694
>
>
> BTW Mark - why did you rename the workflow file from .t2flow to .xml ..?
>
> --
> Stian Soiland-Reyes, myGrid team
> School of Computer Science
> The University of Manchester
>



-- 
Stian Soiland-Reyes, myGrid team
School of Computer Science
The University of Manchester

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