On 21 Mar 2008 at 13:40, DeVolder Carol L wrote: > > Iproniazid was first synthesized as rocket fuel. Then it became used as > an anti-TB drug, then an antidepressant, but then it was too dangerous > and discontinued. But it paved the way for other ADs.
Thank you Carol, and Doug Wallen too, and others who also contributed. Iproniazid checks out, and also hydrazine. Leslie Iverson, an eminent pharmacologist at Oxford, writing in Nature (and what could be more impeccable of references than these) had this to say about the pair in a book review of _Intoxicating Minds_ (2001): "Did you know, for example, that the first antidepressant drug, the hydrazine derivative iproniazid, originated in part because Germany was left with a large stock of unused hydrazine rocket fuel at the end of the Second World War?" (Presumably this is further documented in _Intoxicating Minds_). I thought I did (only it was iproniazid, not chlorpromazine), then I didn't, and now I do again. Kept me from going nuts. Isn't TIPS (and the Internet) wonderful? Iverson, Leslie. An excavation of the drug myth. Nature 409, 767 (15 February 2001) http://www.nature.com/nature/journal/v409/n6822/full/409767a0.html Stephen ----------------------------------------------------------------- Stephen L. Black, Ph.D. Professor of Psychology, Emeritus Bishop's University e-mail: [EMAIL PROTECTED] 2600 College St. Sherbrooke QC J1M 1Z7 Canada Subscribe to discussion list (TIPS) for the teaching of psychology at http://flightline.highline.edu/sfrantz/tips/ ----------------------------------------------------------------------- --- To make changes to your subscription contact: Bill Southerly ([EMAIL PROTECTED])
